Cell biologist interested in cell cycle control mechanisms
Joined December 2018
- Tweets178
- Following290
- Followers230
- Likes521
Maybe we shouldn't need a licence fee to cut a plasmid!
hocheggerlab.github.io/DNAge…
Everyday cloning work with .dna and GenBank. Tauri and CLI on one Rust engine. An AI agent can drive it via CLI and over MCP while you work in a GUI.
Looking for testers
@rust4bio
Helfrid Hochegger retweeted
Pleased to share 15 amazing international and interdisciplinary PhD projects now available through the FlexCAT MSCA-DN targeting oncogenic β-catenin.
Includes our own project (DC14) hosted here at @SussexUni @BiochemBiomedUS
Deadline 31/10/26 via:
lnkd.in/e9TrJuKT
Excited to share our new @NatureComms paper! We developed C-604, a selective inhibitor of Greatwall kinase, and discovered that cancer cells' sensitivity to it depends on a simple ratio: B55α/Greatwall expression levels.
#CellBiology #CancerResearch
nature.com/articles/s41467-0…
Fantastic team effort led by Robert Zach.
Special thanks to @CR_UK and @wellcometrust for support and the many other authors to make this collaboration possible 🙏. Happy to discuss the work - comments and questions welcome!
Helfrid Hochegger retweeted
Happy 21st Birthday to the GDSC! Celebrating the next two days with colleagues and alumni 🎉
@GDSC_Sussex
This Post is from an account that no longer exists. Learn more
Helfrid Hochegger retweeted
Our new paper has just been published!!
We made a double-degron system combining AID2 and BromoTag to enhance the power of degron. Using this, we were able to strongly inhibit the initiation of DNA replication in human cells, ultimately inducing mitosis without DNA duplication.
Helfrid Hochegger retweeted
Excited to reveal our new chemical-genetic system to inhibit PP2A-B56 phosphatase. We use this to characterise its substrates and roles during mitosis. This is a simple yet powerful approach to inhibit any enzyme/protein relying on SLiM-based interactions
biorxiv.org/content/10.1101/…
Helfrid Hochegger retweeted
The first paper from my research group is published! We engineer the first cell cycle reporters in primary human intestinal monolayers, design a collagen press for optimal imaging, and compile a computational pathway for image analysis. rdcu.be/dMwsA
Helfrid Hochegger retweeted
We're thrilled to share our new preprint: "Evolutionarily Conserved Principles of ESCRT-III-Mediated Membrane Remodeling Revealed by a Two-Subunit Asgard Archaeal System."
biorxiv.org/content/10.1101/…
Helfrid Hochegger retweeted
2️⃣ new publications from Joao Matos and his team with are out now! 🤩 In @CellPressNews the team introduces a new method for investigating filaments. In @Dev_Cell the team characterizes the proteome during meiosis 🧬 ➡️ tinyurl.com/rmv29yzv and tinyurl.com/2b39nf3m
Helfrid Hochegger retweeted
Thread of photographers who patiently waited to capture the shot of a lifetime 🧵
1. Leonardo Sens (3 years)
Helfrid Hochegger retweeted
What the hell Jeremy? What. The. Actual. Hell?!? This broke my brain @ReiterLab. Seriously though, mind blowing. nature.com/articles/s41586-0…
Helfrid Hochegger retweeted
Excited to share our work @JCellBiol! We find that chromosome size-dependent spindle forces impair mammalian mitotic error correction of long chromosomes. Congrats to graduate student
@megan_chong who led this work! With Miquel
@RosasSalvans @VannaTran5
rupress.org/jcb/article/223/…
Helfrid Hochegger retweeted
The Cell Cycle Club meeting is back, in-person @TheCrick London, June 4 & for global participation live streamed for virtual attendees!
PRESENT YOUR WORK?
SUBMIT AN ABSTRACT (deadline 17 May)
ATTEND THE MEETING
Register for this FREE @Abcam event now!
abcam.com/events/london-cell…
Helfrid Hochegger retweeted
So proud to announce that we’ve launched the new Sussex Cancer Research Centre spanning @BSMSMedSchool @SussexUni @uniofbrighton, @UHSx_Research, @ESHTNHS and NHS trusts across Sussex.
Read more, come to the launch event, and follow us:
sussexcancer.org
@Sussex_Cancer
Helfrid Hochegger retweeted
I'm really excited to announce that our brand new MRes in Advanced Artificial Intelligence is now available on the @SussexUni website sussex.ac.uk/study/masters/c…! This course offers research focused training in how to be an effective and responsible AI scientist or engineer.
Helfrid Hochegger retweeted
On our paper: Interesting Insight into the Relationship Between TP53, Telomerase, and Telomere Length – Fight Aging! fightaging.org/archives/2024…
Helfrid Hochegger retweeted
🚨 Last call! Love it or hate it, we need your feedback! Please complete the survey!
🙏
Naparistas, or anyone who does image analysis in Python — reminder — we want to hear from you! Please fill in our survey, which will close at the end of Feb 23 Anywhere on Earth! What do you *really* have better to do on Friday night, hmmm? 😂 Thank you!
bit.ly/napari-survey-2023-t