MD. Cardiology. Often smells like ultrasound gel. Also likes crossfit.
Aarhus, Danmark 🇩🇰
Joined March 2019
- Tweets383
- Following1.4K
- Followers285
- Likes4.6K
Halvor Guldbrandsen retweeted
Proud to present the hemodynamic effects of lactate infusion in #cardiogenicshock at @escardio #ACVC2025: Increased CO due to increased SV, enhanced ventriculo-arterial coupling and improved mitochondrial function 🫀
Full article published in @Crit_Care
doi.org/10.1186/s13054-025-0…
Halvor Guldbrandsen retweeted
1,3‐butanediol improves cardiac function in heart failure patients, offering potential for sustained ketosis therapy. #AHAJournals @HalvorOG @GNigopan @K_Hylleberg @OHorsdal @KrisBergHansen @AUHCardio ahajrnls.org/3EbE2qr
Halvor Guldbrandsen retweeted
This was a tough one. 40000 abstracts screened. Limited evidence for the use of calcium for Hyperkalaemia
Pharmacological Interventions for the Acute Treatment of Hyperkalaemia: A Systematic Review and Meta-analysis - Resuscitation resuscitationjournal.com/art…
@LarsWAndersen1
Halvor Guldbrandsen retweeted
Thrilled to share our new study published in @_JCBFM (journals.sagepub.com/doi/10.…)! We show that targeting Na,K-ATPase-dependent Src kinase activation can prevent 🧠 hypoperfusion and exaggerated NVC in a an awake mouse model of familial hemiplegic #migraine.
Here’s a short 🧵
In HFrEF patients, exogenous ketone body therapy improves cardiac function. But they have a short half life.
Here we show prolonged ketosis and cardiac benefit with 1,3-butanediol in HFrEF patients🫀❤️🔥
@KrisBergHansen @OHorsdal @GNigopan
ahajournals.org/doi/10.1161/…
Halvor Guldbrandsen retweeted
Happy holidays 🍾
Proud to share our recent publications on the neurohormonal effects of #ketone ester treatment and the cardiovascular effects of the novel ketone compound 1,3-butanediol in #heartfailure
@HalvorOG @GNigopan @OHorsdal @NikolajRittig
doi.org/10.1161/CIRCHEARTFAI…
Halvor Guldbrandsen retweeted
Increasing #PEEP in AMI-CS unloads the LV without altering cardiac output or cardiac efficiency.
PEEP could be a viable treatment option if titrated optimally during AMI-CS
Now online ahead of print in @_Anesthesiology
⬇️
doi.org/10.1097/ALN.00000000…
@steffen_chr @KrisBergHansen
Halvor Guldbrandsen retweeted
"Today I wouldn't get an academic job. It's as simple as that. I don't think I would be regarded as productive enough."
Nobel Laureate Peter Higgs explains how the focus on quantified indicators (number of publications, citations) harms scientific progress.
Halvor Guldbrandsen retweeted
🫀Hemodynamic effects of lactate infusion🫀
As presented at ESC 2023 and now published, lactate infusion increased cardiac output and peripheral perfusion through afterload decrease.
Lactate could be an alternative fuel for the starving heart.
link.springer.com/10.1186/s1…
Halvor Guldbrandsen retweeted
Reflecting on the 2-year mark since the HPI scandal, a journalist delves into the aftermath (link).
Today, my scientific integrity is restored to the extent possible by the A&A erratum describing a fatal error. Scientists increasingly recognize this.
health.medarbejdere.au.dk/en…
Halvor Guldbrandsen retweeted
Check out our new #ClinSci publication, which reviews the implications of the Na,K-ATPase in #stroke, #migraine, and #hypertension: portlandpress.com/clinsci/ar…
The #review includes a #proteomics analysis revealing reduced expression of the Na,K-ATPase after stroke🧠
Please RT!
🧵 1/3
Halvor Guldbrandsen retweeted
💎 New research!
🎓In @JACCJournals, @KrisBergHansen et al demonstrated that treatment with #ketones improved hemodynamics in patients with #cardiogenicshock.
link: jacc.org/doi/10.1016/j.jchf.…
@GNigopan @K_Hylleberg @steffen_chr #CardioTwitter
Halvor Guldbrandsen retweeted
Defensive medicine gone mad. 601 trips to hospital for CT, 5 bleeds identified, no intervention for any. In this population, chronic subdural haematoma is the only diagnosis for which surgery might be considered, depending on how the patient is - so perhaps we should start there.
Halvor Guldbrandsen retweeted
Our PERFECT trial finally out in @TheLancet !
Pragmatic Nordic 🇫🇮🇳🇴 multicenter RCT comparing appendectomy within 24h versus 8h.
1803 patients!
No difference in rate of perforated appendicitis (9% vs 8%).
👉 Allows to postpone appendectomy to daytime.
authors.elsevier.com/a/1hluD…
Halvor Guldbrandsen retweeted
Provoking trial from 🇩🇰 investigators
Does ultrasound in suspected pulmonary embolism safely reduce referral to diagnostic imaging? – a randomized controlled trial
By Casper Falster 🙏
@ErsPvd @EuroRespSoc
#pulmonary #Embolism #echofirst – at Milan, Lombardy
Hello #echofirst #CardioTwitter #MedTwitter
In a HFrEF pt who develops spontaneous echo contrast (“smoke”), and who is not already in anticoagulation therapy (or platelet-inhibitor), what’s your treatment strategy? And any evidence to support it? – at Favrskov, Danmark
Halvor Guldbrandsen retweeted
Delighted to share our recent paper in @JACCJournals #JACCHF
In patients with #Cardiogenicshock, treatment with #ketone ester was associated with favorable hemodynamic effects 🫀⚡️
@GNigopan
@K_Hylleberg
@steffen_chr
➡️Editorial by Lopaschuk & Karwi
authors.elsevier.com/a/1hPJs…
Halvor Guldbrandsen retweeted
We prefer to be called endocrinologists 🤣 #EndoTwitter
