Hopkins Lab UW (@HopkinsLabUW) header
Hopkins Lab UW (@HopkinsLabUW) profile picture

Hopkins Lab UW

@HopkinsLabUW

Official twitter of the Hopkins Group at @UWaterloo 🥼🧪 Using Differential Mobility Spectrometry and #MassSpectrometry to its full analytical potential

 Waterloo, Ontario, Canada
uwaterloo.ca/hopkins-lab/
Joined March 2021
  • Tweets75
  • Following157
  • Followers225
17Media
Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)Photo by Hopkins Lab UW (@HopkinsLabUW)
And that's a wrap on thesis writing - just in time to celebrate at #ASMS2023! Thank you to all the #TeamMassSpec members and @UWaterloo friends who have made my PhD journey especially memorable.
Image from Christian Ieritano (@cieritano)
3
1
1
38
2,141
Here’s a fun paper that we just published in JCIM: machine learning to correlate LC retention times with molecular partition coefficients. pubs.acs.org/doi/10.1021/acs…
Using Machine Learning To Predict Partition Coefficient (Log P) and Distribution Coefficient (Log...

Using Machine Learning To Predict Partition Coefficient (Log P) and Distribution Coefficient (Log...

Abstract. During preclinical evaluations of drug candidates, several physicochemical (p-chem) properties are measured and employed as metrics to estimate d

pubs.acs.org
1
4
12
1,034
Happy to announce the publication of my new textbook, An Introduction to Spectroscopy and Quantum Structure. cambridgescholars.com/produc…
3
3
17
1,107
Please RT. Our lab will hold the 2023 Summer School on Computational Tools for Structural Interpretation of Ion Mobility Spectra on March 13-15, 2023, online and in-person. Free registration and more information: chem.fsu.edu/ims-summerschoo…. @asmsnews @ISIMSSociety @FemalesInMS
Image from Bleiholder Group (@BleiholderFSU)
3
36
60
(sigma)-Holes in Iodonium Ylides: Halogen-Bond Activation of Carboxylic Acids, Phenols and Thiophenols May Enable Their X-H Insertion Reactions (Hopkins, Murphy et al.) @MurphyLabUW @HopkinsLabUW onlinelibrary.wiley.com/doi/…
Image from ChemEurJ: Chemistry - A European Journal (@ChemEurJ)
3
18
Hey #TeamMassSpec @ScoHoDigDaSnow and I are proud to share our @PCCP perspective on what ions do inside a DMS/FAIMS cell. But don't panic, because this hitchhiker's guide to DMS translates the field into a language understandable by all academic levels. pubs.rsc.org/en/content/arti…
The hitchhiker's guide to dynamic ion–solvent clustering: applications in differential ion mobility...

The hitchhiker's guide to dynamic ion–solvent clustering: applications in differential ion mobility...

This article highlights the fundamentals of ion–solvent clustering processes that are pertinent to understanding an ion's behaviour during differential mob

pubs.rsc.org
1
5
15
Hopkins Lab UW retweeted
Katie Gitin (@GitinKatie) profile picture
Katie Gitin@GitinKatie13 May 2022
#asms2022 attendees: Register at the link below to attend @SCIEXnews's Sunday Symposium and daily breakfast seminars #MassSpectrometry sciex.com/events/asms-2022
2
2
Hopkins Lab UW retweeted
Tom Brady (@TomBrady) profile picture
Tom Brady
@TomBrady13 Mar 2022
These past two months I’ve realized my place is still on the field and not in the stands. That time will come. But it’s not now. I love my teammates, and I love my supportive family. They make it all possible. I’m coming back for my 23rd season in Tampa. Unfinished business LFG
Image from Tom Brady (@TomBrady)
Image from Tom Brady (@TomBrady)
22,242
115,467
88,324
547,881
So you've heard of chiral derivatization, but have you ever seen it done during electrospray just by protonation? Neither had we until recently! Check out our report of this strange behaviour, which is now available in @angew_chem onlinelibrary.wiley.com/doi/…
2
4
11
Hopkins Lab UW retweeted
Konermann Lab (@KonermannLab) profile picture
Konermann Lab@KonermannLab10 Sep 2021
Elnaz (@AliyariElnaz) did some great work looking at non-specific protein complex formation during the ESI process. Lot’s of cool atomistic insight you can check out below! pubs.acs.org/doi/10.1021/acs…
Atomistic Insights into the Formation of Nonspecific Protein Complexes during Electrospray Ioniza...

Atomistic Insights into the Formation of Nonspecific Protein Complexes during Electrospray Ioniza...

Abstract. Native electrospray ionization (ESI)-mass spectrometry (MS) is widely used for the detection and characterization of multi-protein complexes. A w

pubs.acs.org
8
23
Hopkins Lab UW retweeted
Konermann Lab (@KonermannLab) profile picture
Konermann Lab@KonermannLab6 Aug 2021
Doug shows us how covalent modifications can reveal the protein ionization mechanism during the ESI process. Check it out! sciencedirect.com/science/ar…
9
32
🔔Reminder!🔔 Walk-in spots for FIRST dose are available today at 99 Regina Street, for anyone 18+. For all first-dose walk-in clinics visit regionofwaterloo.ca/VaccineC…
Image from Region of Waterloo (@RegionWaterloo)
1
38
27
A machine learning assisted calibration allows collision cross sections to be determined on DMS/FAIMS platforms! Check out our latest publication in @an_chem. Stay tuned for upcoming Star Wars themed papers and other cool ML applications of DMS data. pubs.acs.org/doi/10.1021/acs…

Determining Collision Cross Sections from Differential Ion Mobility Spectrometry

Abstract. The experimental determination of ion-neutral collision cross sections (CCSs) is generally confined to ion mobility spectrometry (IMS) technologi

pubs.acs.org
11
1
13
Hopkins Lab UW retweeted
Elisa Granato (@Prokaryota) profile picture
Elisa Granato@Prokaryota25 May 2021
Peer reviewer alignment chart
Image from Elisa Granato (@Prokaryota)
20
399
125
1,999
Chondroitin sulfate disaccharides with all known motifs of sulfation are unambiguously distinguishable with cryo IR spectroscopy. Unique conformational constraints leave imprints in the spectra depending on sulfation & charge @pagelgroup @cphglyco ow.ly/xFpD50EPt07
Image from The Journal of Physical Chemistry (@JPhysChem)
3
7
New release of MobCal-MPI (v1.2) for calculating collision cross sections! Now includes a graphical interface for input file generation, output file processing, and extensive documentation for source-code compilation. Try it out! github.com/HopkinsLaboratory… #TeamMassSpec
2
2
Our latest benchmark of MobCal-MPI for parallelized collision cross section calculations is now in press. Several DFT and semi-empirical methods (eg. PM7) give CCSs that agree with <3% error from experimental value. Stay tuned for more😀 sciencedirect.com/science/ar… #TeamMassSpec
4
11
Load more