Hungoo Lee retweeted
@HungooLeeLab is hiring! We are seeking highly motivated postdoc researchers and graduate students. Please visit our website for more details. hungooleelab.org/
Hungoo Lee retweeted
CBX2 paper now published in G&D.
Main conclusions:
1) CBX2 (cPRC1) function is specific to committed progenitors, not stem cells
2) Histone modification (H3K27me3) alone is not sufficient - proteins binding them are also critical for cell fate.
pubmed.ncbi.nlm.nih.gov/3755…
We posted a preprint on cPRC1!
Fly Polycomb(Pc) protein became 5 CBX proteins in mammals.
What do they do in adult animals?
Are they specific to adult stem cells like BMI-1?
Or are they general epigenetic factors required in all dividing cells?
biorxiv.org/content/10.1101/…
Hungoo Lee retweeted
A method of correcting the Fragile X defect: Inducing CGG repeat contraction by recruiting the cell's own repair machinery
(Hint: R-loops)
Congrats to Hun-Goo Lee ++
And much gratitude to FRAXA and the Pierce Family Fragile X Foundations!
sciencedirect.com/science/ar…
Hungoo Lee retweeted
#pieintheskychallenge @XistHarvard Jeannie Lee's lab was nominated for #pieintheskychallenge by Dave Bjork from FRAXA foundation, and here's our videos for the pie in the sky Challenge! To help raise awareness and funds we made a short video about Fragile X syndrome.