@IOCBTech

IOCBTech is a technology transfer office of IOCB Prague. It focuses on transferring the top basic research, such as medicinal chemistry, to human use.

 Flemingovo n. 2, 166 10 Prague
iocbtech.cz/
Joined August 2019
  • Tweets598
  • Following530
  • Followers1.2K
242Media
From energy and metabolic sensors to organellar signaling, autophagy, ageing, cancer metabolism, immunity & infections — bridging basic science with clinical insights. #MetabolismSymposium
1
2
1
194
Exciting news! @paulo_paioti from @IOCBPrague @CzechAcademy receives #ERCStG for the project AtropShape: Catalytic Atroposelective Synthesis for Revealing Elusive Bioactive Conformations and Shapes. Congrats, Paulo! This is the fifth active @ERC_Research grant at IOCB Prague, and the eighth in total. ⤵️
Dr. Paulo Paioti, head of the Catalytic Synthesis of Bioactive Molecules group at IOCB Prague (Photo: Tomáš Belloň/IOCB Prague)

ALT Dr. Paulo Paioti, head of the Catalytic Synthesis of Bioactive Molecules group at IOCB Prague (Photo: Tomáš Belloň/IOCB Prague)

1
5
4
36
7,522
Poslední poster mýho PhD studia 🙉🙊
4
1
1
185
6,239
#research #AllostericInhibitors #SARSCoV2 Developing Allosteric Inhibitors of SARS-CoV-2 RNA-dependent RNA polymerase (Janeba) - @ChemMedChem: doi.org/10.1002/cmdc.2024003… @IOCBPrague @CzechAcademy @VSCHT

Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase

Fpocket enables the identification of potential allosteric druggable pocket within the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp), virtual screening leads to an identification of compound 1 as a...

chemistry-europe.onlinelibrary.wiley.com
3
6
562
Události @CT24zive 📺: Lepší diagnostika rakoviny nebo nemocí ledvin - vědci z Ústavu organické chemie a biochemie vyvinuli novou kontrastní látku, která pomůže spojit různé zobrazovací metody. ⏯️: ceskatelevize.cz/porady/1097…
1
2
1
10
1,354
Our newest paper on sugar display on DNA scaffolds and hyper-glycosylated DNA published in @ChemEurJ doi.org/10.1002/chem.2024023… @IOCBPrague @Akademie_ved_CR @science_charles
2
8
1
60
3,192
🌟 Tenure-track alert! Lead a new #CompChem group @IOCBPrague focusing on biomolecular modeling. Generous start-up package included. ✍️ Apply by 31/05/24. #GroupLeader #ChemTwitter #ScienceJobs #ChemistryJobs ➡️ uochb.cz/en/open-positions/2… ⬅️
2
1
517
Our newest paper on the synthesis of base-modified RNA using engineered DNA polymerases published in @NatureComms. Enables construction of hypermodified RNA bearing bulky modifications or site-specifically modified RNA (1). doi.org/10.1038/s41467-024-4… @IOCBPrague @science_charles
10
17
3
92
9,872
IOCB Tech retweeted
BioVaria@BioVaria17 Apr 2024
A very warm #welcome to our new #Silver #Sponsor MSD! In addition, we would like to welcome our new #Startup #Sponsor Kroher Strobel Intellectual Property Law and our new #Partners from Italy UniSMART - Fondazione Università di Padova! #BioVaria2024 #network #lifesciences
2
3
218
"We have finally managed to achieve stability while maintaining reactivity, because these are two main parameters that are opposed to each other," says Veronika Šlachtová on the novel bioorthogonal reaction developed in Milan Vrábel Group @IOCBPrague. english.radio.cz/czech-scien…
2
4
684
Our group website is online! paiotilab.com/ Please contact me if interested in developing innovative catalytic methods and strategies for synthesis of drug-like molecules. Please RT

Paioti Research Group

IOCB Prague

paiotilab.com
3
19
1
78
13,890
The winner of the 🏆"#BioVaria Emerging Startup Award" is: pre-seed #startup team of #Ceridwen Oncology Ltd. They won w/ new therapeutic assets for #cancers using a unique group of factors in #cancer cells for rare fatal #bonecancer #chordoma therapy. Congratulations!
1
1
195
✨TT Day 2022 odstartoval! Které technologie nakonec zvítězí ve finálovém souboji? ➡️Přenos můžete sledovat online zde: youtube.com/watch?fbclid=IwA…

Transfera Technology Day 2022

Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

youtube.com
3
1
6
IOCB Tech retweeted
IOCB Tech@IOCBTech24 Nov 2022
it's happening right now: our CEO Martin Fusek together with @SlamaOtomar (#CUIP), @JaromirZahradka (@ini_Prague #InIBiotechFund), @krechl (@CzechInvest_CZ) & minister @H_Langsadlova in a discussion about #TechTransfer in #CZ
1
1
2
Great work by Lukas Tenora and Pavel Majer from @IOCBPrague with researchers from Johns Hopkins Uni. They converted a known toxic cytostatic molecule into harmless one that gets activated only in cancer tissue. Clinical trials in humans are ongoing. science.org/doi/10.1126/scia…

Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug

DRP-104 is bioactivated in tumor while bioinactivated in the gut, providing robust anticancer activity with minimal toxicity.

science.org
6
35
🎙️ Nejen o práci ve vědě v Americe, ale hlavně o svém výzkumu neurosteroidů a objevování nových látek pro léčbu nemocí povídala v Hovorech Naděždy Hávové na @CROPlus Eva Kudová z ÚOCHB @Akademie_ved_CR ⤵️ plus.rozhlas.cz/v-americe-se…
2
5
IOCB Tech retweeted
LSG2G@LGet2gether10 Oct 2022
LSG2G - Reloaded - Invitation - November 4, 2022 - 11 am - Silberwirt, 1050 Wien, Austria - mailchi.mp/2978f0e94f5d/lsg2…
1
1
1
HLASTE SE! Pamětní grant Martiny Roeselové (NF @IOCBTech) poskytuje roční stipendium 150 tis. Kč vědkyním/vědcům z přírodních věd, kteří se snaží skloubit vědeckou činnost s péčí o dítě. #Deadline pro podávání žádostí o grant na rok 2023 je 15.10. 👉 nfiocbtech.cz/grant 👈
9
15
Our new paper on traceless enzymatic synthesis of hypermodified functionalized DNA polymers from RNA templates using DNA polymerases: doi.org/10.1039/D2CC03588J @IOCBPrague @CzechAcademy @science_charles
2
15
56
Řady výzkumníků VŠCHT Praha rozšířil špičkový zahraniční odborník Andrea Brancale z @cardiffuni s cílem vybudovat na univerzitě novou excelentní výzkumnou skupinu a produkovat vysoce kvalitní vědecké výstupy v oblasti medicinální chemie. vscht.cz/popularizace/media/…
5
2
11
Load more