Biomolecular NMR at IOCB Prague
Prague, Czech Republic
Joined October 2016
- Tweets73
- Following228
- Followers174
- Likes199
IOCBioNMR retweeted
Exploring unsettled biomolecular interactions with an NMR twist. A joint effort with the Obsil lab. @IOCBioNMR nature.com/articles/s41467-0…
IOCBioNMR retweeted
#research #structuralbiology #chromatin #LEDGF #cryoEM
Multivalency of nucleosome recognition by LEDGF (@vaclav_veverka) - @nar_open: academic.oup.com/nar/advance…
@eshusha @IOCBPrague @science_charles
IOCBioNMR retweeted
Although we were not successful in resolving the central IDR from LEDGF bound to nucleosomal DNA using #cryoEM, we stumbled upon an unexpected H3K36 methylation-independent docking site for its PWWP domain. This story was just published in @NAR_Open and is summarized by @eshusha
Well, here comes the first first-author publication at @IOCBPrague and @science_charles ... 😌 *so* relieved and proud to see this story out in @NAR_Open !
academic.oup.com/nar/article…
If you’re into some #chromatin structural biology, please do carry on 🧵👇🏻
IOCBioNMR retweeted
We are looking for a PhD student to join our lab at @IOCBPrague to study chromatin associated complexes. #structuralbiology
#nmr #cryoem #transcription #epigenetics @iocbionmr uochb.cz/en/open-positions/2… instagram.com/p/ChsE3UfDw2C/…
IOCBioNMR retweeted
Our awesome collaboration with @vaclav_veverka @hodgeshc @AdelmanLab @zegerdebyser @zeunas @PavelSrb Vanda Lux + many others was just published in Science, where we reveal new roles of unstructured protein in transcription. (1/8) science.org/doi/10.1126/scie…
IOCBioNMR retweeted
Katerina Cermakova, Jonas Demeulemeester (@zeunas) and Vanda Lux - you have done an amazing job - big respect! Great support from all co-authors! @IOCBPrague @bcmhouston @KU_Leuven @harvardmed @science_charles
@ScienceMagazine: science.org/doi/10.1126/scie…
uochb.cz/en/news/366/study-h…
IOCBioNMR retweeted
Researchers led by @hodgeshc @bcmhouston & @vaclav_veverka @IOCBPrague discovered how disordered protein interactions coordinate the assembly of proteins controlling gene expression.
@sciencemagazine: science.org/doi/10.1126/scie…
Full story: uochb.cz/en/news/366/study-h…
IOCBioNMR retweeted
What is Edward Curtis' @IOCBPrague favorite place on earth? Find out on his #IntroducingAngewandte page onlinelibrary.wiley.com/doi/… teapawt.net/angew_chem/status/1464…
Supernova: A Deoxyribozyme that Catalyzes a Chemiluminescent Reaction (Curtis) @IOCBPrague #FunctionalDNA #openacccess onlinelibrary.wiley.com/doi/…
IOCBioNMR retweeted
Stellar glowing DNAzyme from the #Curtislab @IOCBPrague. Awaiting future exciting applications! Congratulations
onlinelibrary.wiley.com/doi/…
With a careful experimental design, one round of selection can lead to functional deoxyribozymes. Excellent idea!
Accelerated deoxyribozyme evolution. Experimental proof of a clever idea. Well done #Curtis lab @IOCBPrague academic.oup.com/nar/advance…
IOCBioNMR retweeted
. @SciReports (open) N-Glycosylation can selectively block or foster different receptor–ligand binding modes, Joni Vuorio, Jana Škerlová, Milan Fábry, Václav Veverka, Ilpo Vattulainen, Pavlína Řezáčová & Hector Martinez-Seara* @IOCBPrague nature.com/articles/s41598-0… #NMRchat #NMR
It's so exciting to follow the research progress on a protein that spent its early days in the NMR tube. DDI2 has an important role in proteostasis, as shown in vivo by our colleagues from @Konvalinka_Lab @IOCBPrague #proteasome #ubiquitin #immunity
biorxiv.org/content/10.1101/…
Our structural work in the new paper.
Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival mdpi.com/965962 via @MDPIOpenAccess @IOCBioNMR @hodgeshc
IOCBioNMR retweeted
Tento čtvrtek budeme s Davidem Hokszou z @matfyz a @vaclav_veverka z @IOCBPrague diskutovat v live stream (facebook.com/events/14755310…) o průlomu v predikci proteinové struktury a jeho důsledcích. Přidejdte se ! #AlphaFold #casp14 @UniKarlova
Never used so many biophysical techniques in one project...from paramagnetic NMR through AUC and X-ray crystallography to mass spectrometry.
Officially a structural biologist. Congratulations Vanda!
cell.com/structure/fulltext/…
CK2 regulatory role for LEDGF interactome confirmed!
Paradox role for LEDGF/p75: Competition between PAF1 and MLL1/COMPASS confers the opposing function of LEDGF/p75 in HIV latency and proviral reactivation advances.sciencemag.org/cont…
IOCBioNMR retweeted
@IOCBioNMR contribution to understanding the calcium sensing mechanism by the transmembrane segment of Bordetella adenylate cyclase toxin @BBAjournals #biomembranes. sciencedirect.com/science/ar…
N-glycosylation caught responsible for modulating receptor-ligand interactions @IOCBPrague biorxiv.org/content/10.1101/…
Excellent science!
Our new paper in @embojournal: on a bacterial rhomboid protease and its ancestral pseudoprotease function analogous to rhomboid‐family client adaptors in eukaryotic ERAD. Great collaboration with @IOCBioNMR and @doan_thierry! embopress.org/doi/10.15252/e…
IOCBioNMR retweeted
Please RT – #PhD @IOCBPrague - Check 35 available #PhDprojects in 18 IOCB groups from CHEM, BIO, and PHYS clusters including @PetrBeier @hocekm @CahovaB @Konvalinka_Lab @tomas_pluskal @IOCBioNMR labs:
uochb.cz/en/call-for-phd-app…
