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Iyengar's lab

@IyengarLab

Systems Therapeutics Lab at Icahn School of Medicine at Mount Sinai, NYC

iyengarlab.org
Joined November 2020
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Photo by Iyengar's lab (@IyengarLab)Photo by Iyengar's lab (@IyengarLab)Photo by Iyengar's lab (@IyengarLab)
Happy to share that our dynamic model of vesicle transport and microtubule growth during neurite outgrowth has been suggested for presentation on Kudos, a science platform for a non-specialist audience. growkudos.com/publications/1…

Top-down based dynamic modeling to identify pathway dependencies during neurite outgrowth

Neurite outgrowth describes the formation and extension of a long cellular protrusion from the cell body of a neuron. This growing neurite will finally become the axon connecting the neuron to other...

growkudos.com
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Article:Whole cell response to receptor stimulation involves many deep and distributed subcellular biochemical processes. sciencedirect.com/science/ar…
Image from Iyengar's lab (@IyengarLab)
Extracellular histones, a new class of inhibitory molecules of CNS axonal regeneration. academic.oup.com/braincomms/… Video:youtube.com/watch?v=eaYO-KIb…
Image from Iyengar's lab (@IyengarLab)
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Functional Effects of Cardiomyocyte Injury in COVID-19. J Virol. 2021 Oct 20;JVI0106321.doi: 10.1128/JVI.01063-21. pubmed.ncbi.nlm.nih.gov/3466… & journals.asm.org/doi/10.1128…
Image from Iyengar's lab (@IyengarLab)
Paper - The Enemy Within Sudden-Onset Reversible Cardiogenic Shock With Biopsy- Proven Cardiac Myocyte Infection by Severe Acute Respiratory Syndrome Coronavirus 2 drive.google.com/file/d/1eYf…

The_Enemy_Within_AaronWeiss.pdf

drive.google.com
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Paper - A Microglial Subset at the Tumor-Stroma Interface of Glioma biorxiv.org/content/10.1101/…
Love this: combined basic in vitro and clinical studies to assess an important pathogenesis question. Study describes effects on myocardial cells from combination of infection and cytokines. Heart muscle damage needs follow up studies. Part of long COVID? medrxiv.org/content/10.1101/…
Physiology of cardiomyocyte injury in COVID-19

Physiology of cardiomyocyte injury in COVID-19

COVID-19 affects multiple organs. Clinical data from the Mount Sinai Health System shows that substantial numbers of COVID-19 patients without prior heart disease develop cardiac dysfunction. How...

medrxiv.org
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biorxiv.org/content/10.1101/… Collaborative paper with Chris Cardozo’s lab
The human ApoE4 variant reduces functional recovery and neuronal sprouting after incomplete spinal...

The human ApoE4 variant reduces functional recovery and neuronal sprouting after incomplete spinal...

Spinal cord injury (SCI) is a devastating form of neurotrauma. Patients who carry one or two ApoE4 alleles show worse functional outcomes and longer hospital stays after SCI but the cellular and...

biorxiv.org
medrxiv.org/content/10.1101/…
Physiology of cardiomyocyte injury in COVID-19

Physiology of cardiomyocyte injury in COVID-19

COVID-19 affects multiple organs. Clinical data from the Mount Sinai Health System shows that substantial numbers of COVID-19 patients without prior heart disease develop cardiac dysfunction. How...

medrxiv.org
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