Drinking 2–3 cups of coffee daily is associated with a lower risk of type 2 diabetes Both caffeine and chlorogenic acids can activate AMPK, a cellular regulator that ramps up fat-burning and glucose uptake while dialing down growth pathways This is the same energy-sensing pathway activated by fasting and exercise, offering one potential explanation for coffee’s link to better metabolic health Coffee may also influence glucose regulation through reduced inflammation and changes in gut bacteria

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