Postdoctoral Research Fellow @iHealthSportVU
Melbourne, Victoria
Joined May 2018
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James Broatch retweeted
New study led by James Broatch investigating the effects of exercise intensity on fitness & brain health markers in sedentary middle-aged adults: neurology.org/doi/pdfdirect/…
James Broatch retweeted
Your brain has an overnight clean-up crew while you sleep & exercise might help it work better. 🧠😴 🏋️♀️
Watch Dr James Broatch from Victoria University explain it on the Nine Today Show this morning bit.ly/4he0Gjw,
and read the full study 👉 bit.ly/4pnVrjh
James Broatch retweeted
Research Fellow position in my lab.
We're looking for a molecular biologist with cell culture experience to discover new biological roles for lactate as a regulator of skeletal muscle.
🗓️ Closing date: 24 Jul 2026
More info here: bit.ly/3ReFUFQ
James Broatch retweeted
Pleased to be involved in the review - led by James Broatch.
Exercise as a regulator of glymphatic function sciencedirect.com/science/ar…
James Broatch retweeted
New ARC Research Fellow position available in my lab.
We're looking for a molecular biologists to discover new biological roles for lactate as a regulator of skeletal muscle adaptations.
Closing date: 10 Jul 2026
More info here: fa-ercy-saasfaprod1.fa.ocs.o…
James Broatch retweeted
Sleep health has substantial impact across the whole body, as nicely summarized in this new paper
cell.com/cell-reports-medici…
James Broatch retweeted
The more exercise in mid- and late-life, the less Alzheimer's and all-cause dementia, adjusted for all known risk factors
jamanetwork.com/journals/jam…
James Broatch retweeted
Effects of 8-Week High-Intensity Interval Training Intervention Regulating the SIRT1/PGC1α Pathway on Hippocampal Neuron Injury and Cognitive Impairment in Obese Rats
🔎"This study findings are consistent with previous research findings, which demonstrate that obesity leads to hippocampal neuronal damage and cognitive decline in behavior. Subsequent exercise intervention experiments found that 8-wk HIIT reduced the weight and Lee index of obese rats, ameliorated their cognitive behavior and neuronal pathology levels, and increased the expression of Sirt1 in the hippocampus of rats. Further protein-level experiments in hippocampal and prefrontal cortex tissues revealed that the SIRT1/PGC1α pathway was significantly downregulated under the influence of obesity, whereas HIIT activated the SIRT1/PGC1 α pathway to ameliorated cognitive dysfunction induced by obesity in rats."
cdn.nutrition.org/article/S2…
James Broatch retweeted
Lancet Neurology article emphasizing lifestyle interventions including nutrition, sleep, stress management and exercise for not only symptom management but also disease modification in Parkinson’s. Lifestyle is not fringe!
thelancet.com/journals/laneu…
James Broatch retweeted
This expert consensus statement provides an evidence-based summary of the impact of physiological factors, physical activity guidelines, and barriers on physical activity participation and prescription for individuals with disabilities, providing practical recommendations for prescribing and designing physical activity programs tailored to adults with disabilities.
James Broatch retweeted
Exercise intensity matters: the effects of aerobic exercise intensity on muscle-derived neuroprotective myokines
Peripheral & systematic mechanisms through which exercise-induced myokines impact brain function👇🏼
#exercise #muscle #brain #health
pmc.ncbi.nlm.nih.gov/article…
James Broatch retweeted
Nice new reviews on the neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing bit.ly/47yBMpr
James Broatch retweeted
Exercise Intensity Terminology is a bit of a mess 😵💫
Our attempt to try & summarise some of the different approaches, and make some recommendations going forward, has finally been published in both MSSE: bit.ly/4nT7Pq5 & JSaMS: bit.ly/46U7ptq.
We have a funded PhD position available to domestic students, commencing Q1 2026
Project: 'Tracking dementia resilience using novel biomarkers of exercise neuroprotection'
🗓️Open until filled
✅Eligibility: Domestic (Aus/NZ) citizens/P.R.
More info: vu.edu.au/study-at-vu/fees-s…
James Broatch retweeted
Our latest collaborative work is now online
doi.org/10.1111/acel.70242
We explored muscle–brain cross-talk and discovered that the muscle-derived cathepsin B (a myokine) plays a key role in improving behavioral and neurogenic deficits in a mouse model of Alzheimer’s disease.
James Broatch retweeted
💊+🏋️♂️= Medicine.
In our latest @TheLancetLongevity paper we argue:
👉 “Exercise prescription is medically indicated, professionally implemented, and clinically monitored.”
It’s time to integrate exercise into medication management for older adults.
Read here ➡️ thelancet.com/journals/lanhl…
James Broatch retweeted
Excited to share our latest pre-print: bit.ly/4lH8AAv
“Exercise induces time-dependent but not sex-specific transcriptomic changes in healthy human skeletal muscle”
Led by @DaleFTaylor with @LizReisman, @bluebirdi, @Romain_Barres, @NolanJHoffman & @JohnAHawley
🧵 1/9
James Broatch retweeted
🧑🔬 NEW PhD scholarship available in my lab to investigate:
"Mitochondrial Adaptations to Exercise" 🚴
🗓️ Applications close: 14 September 2025 ;
✅ Eligibility: Open to Australian & International students
More info here: bit.ly/40PFiIq
James Broatch retweeted
Exercise orchestrates systemic metabolic and neuroimmune homeostasis via the brain-muscle-liver axis to slow down aging and neurodegeneration: a narrative review
eurjmedres.biomedcentral.com…
