#ICU, #Anesthesiology, #criticalcare, #researcher @Duke_Anesthesia interested in #AKI, #renalimmunology, #multiorganfailure. #eSAS. Tweets are my own
Durham, NC
Joined October 2014
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- Following243
- Followers807
- Likes6.7K
Thanks @JCI_insight ! So excited to publish our work on #myeloid IL1 receptor in #glomerulonephritis. @aces_duke @Duke_Anesthesia @DukeKidney
Presenting a novel axis that can fine-tune the immune response to glomerular and tubule cell damage:
Jamie R. Privratsky @JamiePrivratsky & team @DukeKidney @Duke_Anesthesia identify a novel myeloid cell-endothelial cell immunoregulatory axis, supporting a model whereby myeloid IL-1R1 activity constrains ER stress–mediated EBI3/IL27 secretion, thereby attenuating type I IFN expression in kidney endothelial cells and ameliorating
autoimmune nephritis.
The figure shows anti-IFNAR1 therapy abrogates kidney injury after NTS nephritis in mice lacking IL-1R1 specifically in myeloid cells (bottom); littermate controls (top).
#AKI #Nephrology #kidney #macrophage
Check out my lab’s new paper in @JCI_insight - The myeloid IL-1 receptor limits IL-27-mediated endothelial type I IFN during nephrotoxic serum nephritis insight.jci.org/articles/vie… @Duke_Anesthesia @DukeKidney @Yanting17931824 @the_asci
Congrats!
Excited to announce that the Nackley Lab has been awarded a $3 million NIH R01 grant, building on research led by our own Dr. Nathaniel Hernandez (right)!
Learn about the team’s work on how fat cells communicate with the nervous system to influence pain:
anesthesiology.duke.edu/news…
Jamie Privratsky MD/PhD retweeted
Please remember to register for our @Duke_Anesthesia residency virtual open house where there will be an ACES break out room! @DukeOPSD
Jamie Privratsky MD/PhD retweeted
For aspiring physician scientists and training program leaders.
Navigating physician-scientist careers: Insights from American Board of Internal Medicine Research Pathway graduates: 👉 doi.org/10.1172/jci.insight.…
Emily J. Gallagher @IcahnMountSinai et al. & team present the results of a survey carried out by the Alliance for Academic Internal Medicine Research Committee in collaboration with the American Board of Internal Medicine.
@jmvyasmdphd @patrickhu @williams_lab
#PhysicianScientist
Jamie Privratsky MD/PhD retweeted
Interested in a career as a #physicianscientist ? Check out our breakout room during the @Duke_Anesthesia residency virtual open house on August 31!
Jamie Privratsky MD/PhD retweeted
🔬During our residency open house on 8/31, join the Academic Career Enrichment Scholars Program breakout room to learn more about this highly-selective resident research track to gain status as an independently-funded researcher.🔗Register for either/both: duke.is/OpenHouseRegistratio…
ALT An image of the Duke shield and the Academic Career Enrichment Scholars Program logo promoting registration for an open house about this residency research track.
📣Interested in joining our Duke #Anesthesiology family?🗓️Meet some faculty, residents and program leadership at our Virtual Open House: Monday, 8/31 @ 7pm! Discover what makes our community unique, explore our top-tier training, and get your questions answered. Details below👇.
Congrats!!
Check out our new paper - cover story on @NatureNeuro - outlining a potential new target for pain treatment and which may explain the susceptibility of older adults to chronic pain
Jamie Privratsky MD/PhD retweeted
We are excited to announce that Dr. Opeyemi Olabisi will be appointed as the next Chief of Nephrology in the Department of Medicine
medicine.duke.edu/news/dr-op…
Jamie Privratsky MD/PhD retweeted
Congratulations to @AmandaJClarkMD for leading this effort…
A first in the field to show that NAD+ biosynthetic impairment is a quantitative feature of pediatric #AKI
Hopefully opens possibilities for B3 based trials to prevent or improve this important condition in children
AKI is highly prevalent among hospitalized children, but there is no treatment. Read this Original Article on pediatric AKI associated w/impairment in nicotinamide adenine dinucleotide (NAD+) metabolism. @AmandaJClarkMD
link.springer.com/article/10…
Happy birthday old man!
Next year is the scary one! Thank you to everyone who planned the party and showed up (as well as those that couldn’t make it)! @sarah_jane210 @mesmith428 @OuhscN @Maryam7835Bibi
Jamie Privratsky MD/PhD retweeted
Next year is the scary one! Thank you to everyone who planned the party and showed up (as well as those that couldn’t make it)! @sarah_jane210 @mesmith428 @OuhscN @Maryam7835Bibi
Jamie Privratsky MD/PhD retweeted
🎉 Congratulations to Dr. Mara Serbanescu on being awarded @NIH R35 MIRA Grant on “Gut & Blood Microbial Signatures on Immune Phenotypes & Organ Dysfunction in Sepsis.”
It is truly an honor to mentor you & watch grow as a 🌎leader & ⭐️ in ICU Microbiome at @Duke_Anesthesia
#microbiome #anesthesiology
#foamcc
Jamie Privratsky MD/PhD retweeted
It took a while, but the Chamessian Lab finally has a home on the web
chamessianlab.wustl.edu/
We are building a unique program here that integrates the clinical and laboratory efforts to understand and treat patients living with neuropathic pain. Check it out. I welcome any feedback. #neuropathy #pain #neuromodulation #translational
I should add, we will be hiring soon for a scientist to lead our in vivo preclniical animal studies and #iPSC sensory neuron initiatives. Exciting times ahead. Shoot me a message if you want to find out more.
Jamie Privratsky MD/PhD retweeted
Super proud of this team and this work!Couldn't have done it without the best mentorship and department!
@anesthesia_mom @CarvalB @Stanford_obanes @stanfordanes @SOAPHQ @_Anesthesiology
Congrats!
Thanks @jclinicalinvest for highlighting our recent work.
Also wanted to recognize emerging #physicianscientists @VEtzrodtMD @AmandaJClarkMD @MarieChSaade for their contributions and leadership of @UTSWNephrology faculty Takashi Suzuki
Jamie Privratsky MD/PhD retweeted
Thanks @jclinicalinvest for highlighting our recent work.
Also wanted to recognize emerging #physicianscientists @VEtzrodtMD @AmandaJClarkMD @MarieChSaade for their contributions and leadership of @UTSWNephrology faculty Takashi Suzuki
A candidate marker and therapeutic target in sepsis!
ASCI member @samirparikhmd & team show cathepsin K cleavage of angiopoietin-2 produces detrimental Tie2 antagonist fragments in sepsis and inhibition of cathepsin K with odanacatib improved survival in sepsis models: jci.org/articles/view/174135
Jamie Privratsky MD/PhD retweeted
Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells @AshkarLab @jclinicalinvest
