@KevMKnight
Joined December 2017
  • Tweets17
  • Following23
  • Followers14
A universal allosteric mechanism for G protein activation dlvr.it/Rx6LFr
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Kevin M Knight retweeted
Lasker Foundation
@LaskerFDN3 Mar 2021
G proteins are critical for many cellular processes. How does the key step—dissociation of the Gα and Gβγ subunits—occur? New research shows that just three amino acids are responsible: Gly-Arg-Glu. #gpcr @HenrikDohlman ow.ly/kusR50DN3sO
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Thank you to everyone involved in this work, and to my committee for their guidance and support.
BryanRoth
@zenbrainest25 Feb 2021
Intriguing! A universal allosteric mechanism for G protein activation cell.com/molecular-cell/full…

A universal allosteric mechanism for G protein activation

G protein signaling involves binding of agonist to receptor and unbinding of GDP from the G protein. Using integrated molecular and computational approaches, Knight et al. investigate the second,...

cell.com
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Kevin M Knight retweeted
BryanRoth
@zenbrainest25 Feb 2021
Congrats to folks from @UNC_PHCO @ReidHJOlsen @UNC_BCBP and many others (sorry don't have twitter handles for all)!
BryanRoth
@zenbrainest25 Feb 2021
Intriguing! A universal allosteric mechanism for G protein activation cell.com/molecular-cell/full…

A universal allosteric mechanism for G protein activation

G protein signaling involves binding of agonist to receptor and unbinding of GDP from the G protein. Using integrated molecular and computational approaches, Knight et al. investigate the second,...

cell.com
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eurekalert.org/pub_releases/… #healthfacts
Scientists @UNC discover viral barcode that allows gene therapy viral vectors to cross the blood-brain barrier more efficiently: bit.ly/2EPh4mf @UNCMedCenter @UNC_Health_Care Could help create better treatments for brain-related conditions while reducing liver toxicity.
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Kevin M Knight retweeted
BryanRoth
@zenbrainest8 Feb 2018
Please RT: I notice lots of labs are ordering individual GPCRs from our PRESTO-Tango resource @addgene If you're ordering more than a few you could probably save $$ and time by ordering the entire kit which is here: addgene.org/kits/roth-gpcr-p…

Roth Lab PRESTO-Tango GPCR Kit

PRESTO-Tango Kit from Bryan Roth's Lab that allows for measurement of more than 300 GPCRs

addgene.org
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Kevin M Knight retweeted
BryanRoth
@zenbrainest24 Jan 2018
NATURE: Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone nature.com/articles/nature25…
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"If you want a man to keep his head in a crisis, you must give him some training." -Seneca
"Goals achieved with little effort are seldom appreciated and give no personal satisfaction."… instagram.com/p/BdmuxVqnC0O/
"I will get ready and then, perhaps, my chance will come." -John Wooden #morningmeditation… instagram.com/p/BdkKxzPHpzV/
"Do not let what you cannot do interfere with what you can do"- John Wooden #morningmeditation… instagram.com/p/BdhlVhGHlfx/
"Success is never final. Failure is never fatal." -Winston Churchill #morningmeditation… instagram.com/p/Bde_toAHLt9/
"Learn as if you were to live forever; Live as if you were to die tomorrow." -Coach Wooden… instagram.com/p/BdcdoU8HnyU/
Amazing tournament to end 2017 season back in October. #grateful #eevb #backtothegrind @… instagram.com/p/BdVUN-7nHm7/
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