James Kirby retweeted
Burkholderia cepacia causes disease in 🫁 of people with cystic fibrosis, an environment totally unlike standard susceptibility testing conditions. Today at #ASMicrobe Anusha Shukla presented her work on Bcc in artificial sputum medium 🧫🥼🧪 TBKLab.org
James Kirby retweeted
Did you know that avibactam has intrinsic antibacterial activity, mediated by inhibition of penicillin-binding protein 2? Here’s the amazing Dr. Michelle Naegeli @drshigelly presenting a poster from our lab today at #ASMicrobe
James Kirby retweeted
Yanqin Huang of @KirbyLabMicrobe presenting on the all-oral triple combination of omadacycline + azithromycin + clofazimine for M. abscessus #ASMicrobe
Neglected 80-year-old antibiotic is effective against multi-drug resistant bacteria eurekalert.org/news-releases… via @EurekAlert
Congratulations to Yoon-Suk on his new manuscript, where nanoluciferase and Legionella pneumophila meet! - The Kirby Laboratory kirbylab.org/1/post/2023/02/…
RND Pump-Mediated Efflux of Amotosalen, a Compound Used in Pathogen Inactivation Technology to Enhance Safety of Blood Transfusion Products, May Compromise Its Gram-Negative Anti-Bacterial Activity | mSphere journals.asm.org/doi/10.1128…. Our new manuscript!
James Kirby retweeted
Congratulations to Dr. Jeannie Lee (@XistHarvard), recipient of IRSF's Innovation Award Grant. This project focuses on restoring MECP2 in patients to potentially treat and cure #Rettsyndrome. More on research: buff.ly/3Ye0Qed #GeneTherapy
James Kirby retweeted
Plasmid of the Day
pMOD3-mWasabi-nat
Depositor: @KirbyLabMicrobe
Purpose: Bacterial mWasabi promoter trap
hubs.la/Q01gmyrY0
Omicron detected just as well by antigen tests as original (WA1) SARS-CoV-2 strain, but Delta not so well, journals.asm.org/doi/10.1128…. Study performed with live, cultured virus (not heat inactivated or gamma irradiated).
James Kirby retweeted
Congratulations to the awardees of our research funding opportunity @BIDMChealth and IDX20! We look forward to following your progress on #COVID19 research. reaganudall.org/news-and-eve…
What is a Protein? (from PDB-101) youtu.be/wvTv8TqWC48 via @YouTube What a great short video on proteins structure.
From my colleague, Ramy Arnaout, "Visualizing Omicron: COVID-19 Deaths vs. Cases", further enhancements to visualization forthcoming. github.com/rarnaout/Covidcyc…
Our study posted to MedRXiv supports use of SARS-CoV-2 antigen tests to predict infectivity at the time of testing: medrxiv.org/content/10.1101/…
James Kirby retweeted
Happy medical laboratory professionals week! We could not do our jobs without you! We see you and value you. ❤ @Thea_BK @KirbyLabMicrobe Twitterless Robert @romneyinla @RodneyRohde @BurnhamBugDoc and many many others!
It’s Medical Laboratory Professionals Week! Celebrate and thank laboratory professionals for their hard work, dedication, and service.
Know an awesome laboratory professional? Tag them below and visit bit.ly/labweek21.
James Kirby retweeted
"Junk DNA" B2 and ALU make self-cleaving ribozymes!
An honor that our paper was given the Cozzarelli Prize. Congrats to coauthors A Hernandez, @ZovoilisLab, C Cifuentes-Rojas, Lu Han, @Bojan53387482!! @MGHMolBio @MGH_RI
pnas.org/content/117/1/415
The Editorial Board of PNAS has selected six papers published in 2020 to receive the Cozzarelli Prize, an award that recognizes outstanding contributions to the scientific discipline represented by the NAS. See the list of recipients here: ow.ly/8qj750DZaZC
James Kirby retweeted
A Unified View: Motif-driven interactions between RNA and PRC2 are rheostats that regulate transcription elongation !
- resolving the mystery of why RNA-PRC2 complexes occur within active genes, and how specificity is achieved
Free read: rdcu.be/cc2Ee
ALT https://www.nature.com/articles/s41594-020-00535-9
Restoring antibiotic susceptibility in Gram-negative pathogens through plasmid eviction. PNAS manuscript just out.
Discovery of small-molecule inhibitors of multidrug-resistance plasmid maintenance using a high-throughput screening approach pnas.org/content/early/2020/…
James Kirby retweeted
Just accepted!
"Children with asymptomatic SARS-CoV-2 infection had lower levels of virus... than symptomatic children, but timing of infection relative to diagnosis likely impacted levels in asymptomatic children."
bit.ly/3kmAX89 @ASMicrobiology
James Kirby retweeted
1 h malaria detection that meets WHO recommended standards using SHERLOCK system: pnas.org/content/early/2020/…