KOBEMicrollography!Structural biology of infection and immunity lab at UQ

Brisbane, Queensland
Joined May 2022
Structural basis of canonical TIR-NLR activation in plant innate immunity biorxiv.org/content/10.64898… #biorxiv_plants
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Little one’s first interstate conference done #ASBMB2025 Thank you to @ITSASBMB and local organisers @buffalo_berger @Kobe_Lab_ @ UQ for the support! Great conference great to be back!
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I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5) doi.org/10.1101/2025.09.24.6…
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It has been a roller coaster year for me after experiencing extreme happiness and loss. Today I’m starting as a new PI @ANUChemistry. Very grateful to all my extended academic family @BiologyANU and all past and current mentors. Looking forward to forge new networks and collabs!
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This week we had the pleasure of hosting cryo-EM guru @OliBClarke who gave the @UQ_News cryo-EM community a fantastic cryo-EM data-processing workshop. Thank you Oli for sharing your tricks with us, @FarrahBlades for wrangling the Bunya supercomputer, and all who attended! 🔬
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Had a blast the last couple of days learning how to use our brand new Oryx8 crystallisation robot from @DougInstruments! First robot for the lab and first Oryx8 in Australia! 💎 #gulbaliinstitute #charlessturtresearch
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2024 @UQ_SCMB Structural Biology division retreat. Another fantastic three days of science, sun and fun!
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And so it ends … 3 days of fantastic science and beautiful Freo weather #crystal35 #scanz. Thanks to everyone who joined us from Japan, Korea, India, South Africa, Singapore, UK and USA. And of course our amazing Australian and New Zealand structural science community!
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Kobe Lab retweeted
All the rising stars of Crystal35 conference @Crystal_SCANZ 🎉💎🥳👏👍🥂 Congrats everyone
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Kobe Lab retweeted
Exciting session at Crystal35 conference @Crystal_SCANZ with the “rising star awards” starting with @bj_charles @MonashBDI 🎉 congrats
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Congratulations to @JackKClegg for the 2024 SCANZ Mathieson Medal! @RACInational @UQ_SCMB 🥳
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Thank you #crystals35 @Crystal_SCANZ organisers for inviting me to present our @CMMUQ1 work on high-throughput small molecule & protein crystallisation, crystal imaging with Rock Imagers #MicroED Pipeline using Glacious @XUEY85 @JackKClegg @weixi_gu @Kobe_Lab_ @movingwhat @
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We discovered a new immune signaling molecule: N7-cADPR N7-cADPR is produced by phage-stimulated TIR proteins. It activates a bacterial caspase, which then degrades essential proteins to curb infection Preprint: biorxiv.org/cgi/content/shor… Congrats @FrancoisRousset & @IlyaOsterman
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Kobe Lab retweeted
It’s my great honour to be an ARC Future Fellowship 2024 recipient. It’s been a dream start for me to establish my own group @ANUChemistry @ourANU. Thanks to @UQ_SCMB, @UQscience and @CMMUQ1 for supporting my application. We will continue to collaborating closely.
Today, the ARC held an induction for the 2024 Future Fellowship recipients. In attendance were past Fellowship recipients Prof Alan Gamlen (@ourANU), Prof Fleur Johns (@UNSW), and Prof Ilya Mandel (@MonashUni) who shared tips for success on completing a research fellowship.
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Yesterday we celebrated Michael’s nomination to the Research Culture Celebration @Cambridge_Uni. Thanks for making our lab such an enjoyable place to work and learn, Michael!
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Full scholarship available for a curious PhD student to take on one of the most interesting topics in virology: how do capsid proteins assemble into particles with different geometries? Use native MS and cryo-EM with @buffalo_berger at UQ to find out! 🔗griffith.edu.au/research-stu…
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Kobe Lab retweeted
🚀New update to #AlphaFold Database: Foldseek now integrated! Peer deeper into evolution with new structure-based search feature to find similar proteins with remote homology. The search includes experimentally-determined protein structures from @PDBe. ebi.ac.uk/about/news/updates…
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Kobe Lab retweeted
Seminar alert! ⏰Tune in to our @arc_gov_au CCeMMP seminar tomorrow with Prof. Megan O’Mara from @UQ_News on "Exploiting protein/lipid interactions for modulators of chronic pain" - More info: ccemmp.org/events/ccemmp-sem…
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Kobe Lab retweeted
Open postdoc position jointly between the groups of Xiaodong Zou and myself @Stockholm_Uni on MOF synthesis and 3D electron diffraction. Deadline: Oct 1st. #chemjobs #3DED #MOFs su.se/english/about-the-univ…
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Our Centre of Excellence in quantitative microbiology (macsys.org/careers/) is hiring. We need people keen to work across areas of molecular microbiology, biochemistry and ‘omics with partners in maths, stats and physics. careers.pageuppeople.com/513…
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