Lina Siukstaite (@LSiukstaite) header
Lina Siukstaite (@LSiukstaite) profile picture

Lina Siukstaite

@LSiukstaite

PostDoc@NYU #glycobiology

 New York
Joined April 2020
  • Tweets70
  • Following248
  • Followers93
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Photo by Lina Siukstaite (@LSiukstaite)Photo by Lina Siukstaite (@LSiukstaite)Photo by Lina Siukstaite (@LSiukstaite)Photo by Lina Siukstaite (@LSiukstaite)Photo by Lina Siukstaite (@LSiukstaite)Photo by Lina Siukstaite (@LSiukstaite)
Lina Siukstaite retweeted
Minguet_lab (@LabMinguet) profile picture
Minguet_lab@LabMinguet22 Jan 2024
Super proud of Valeria! You will rock it my dear, I we will be there to enjoy it! @CIBSS_UniFR @UniFreiburg @sfb1160
yEFIS (@y_efis) profile pictureyEFIS@y_efis22 Jan 2024
The yEFIS-@EMEUNET joint initiative continues in 2024 with our 2nd joint #webinar on CAR T cell Therapies in #Immunology and #Rheumatology. Join us on January 23rd at 6pm CET for two exciting talks! Free registration at this link: tinyurl.com/yefisemeunet2
Image from yEFIS (@y_efis)
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Lina Siukstaite retweeted
GFRGlyco (@GFRGlyco) profile picture
GFRGlyco@GFRGlyco15 Dec 2023
An updated line-up for GFG2024 congress #glycotime gfg2024.sciencesconf.org/
Image from GFRGlyco (@GFRGlyco)
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Lina Siukstaite retweeted
Taras Sych (@SychTaras) profile picture
Taras Sych@SychTaras16 Jun 2023
Our Single Particle Profiler paper is now available as behind the paper post to protocols and methods springer nature community. Wrote to gether with @SuperSphingoJan . protocolsmethods.springernat…
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#glycotime @omidvar_r @RolandTh1+others propose the dimeric LecA chimeras as transcytotic drug delivery tools through Gb3-positive cellular barriers for future in vivo tests. They conclude that #lectins have excellent potential as drug delivery tools! tinyurl.com/2zbj9v8b
Image from Ashraf Saad, bridging Glycobiology and Oncology! (@AsAshraf123321)
Image from Ashraf Saad, bridging Glycobiology and Oncology! (@AsAshraf123321)
Image from Ashraf Saad, bridging Glycobiology and Oncology! (@AsAshraf123321)
Image from Ashraf Saad, bridging Glycobiology and Oncology! (@AsAshraf123321)
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Interesting! Is there a link between glucose metabolism and cancer immune evasion? Aberrant Glc metabolism produces high levels O-GlcNAc, which suppresses the degradation of PD-L1 in cancer cells, allowing cancer immune evasion. @PNASNews tinyurl.com/2kutufev #glycotime
Image from Marcin Czerwinski (@CzerwinsMarcin)
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Lina Siukstaite retweeted
Alexander Titz (@Titz_Lab) profile picture
Alexander Titz@Titz_Lab7 Mar 2023
New paper by Chris Mueller and Winfried Römer show detrimental effects of P. aeruginosa lectin LecB on immunity that can be blocked with our LecB inhibitor! #glycotime bionity.com/en/news/1179727/…

Pseudomonas aeruginosa Bacteria produce a molecule that paralyzes immune system cells

Bacteria of the species Pseudomonas aeruginosa are antibiotic-resistant hospital germs that can enter blood, lungs and other tissues through wounds and cause life-threatening infections. In a join ...

bionity.com
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Enzymatic Glyco-Modification of Synthetic Membrane Systems, finally published! Please check it out! :) @DylanJabeguero @LabRichter @synBIOcarb @mitrovic_anna_ mdpi.com/2126200 #mdpibiomolecules via @Biomol_MDPI
Image from Lina Siukstaite (@LSiukstaite)
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Another fruitful collaboration! Huge congratulations to everyone involved, especially to @ChaoSU18237931 and @OttLab_Freiburg 🦄🦄🦄nature.com/articles/s41467-0…
Image from Lina Siukstaite (@LSiukstaite)
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Christmas came early!🎄 @wbturnbull @SychTaras @synBIOcarb #glycotime
Marcin Czerwinski (@CzerwinsMarcin) profile pictureMarcin Czerwinski@CzerwinsMarcin5 Dec 2022
Biotinylated protein derived from cholera toxin becomes a fusogenic lectin upon cross-linking with streptavidin, binding to glycolipids and causing hemifusion and fusion of vesicles @LSiukstaite @wbturnbull tinyurl.com/yrhdurx6 #glycotime
Image from Marcin Czerwinski (@CzerwinsMarcin)
Image from Marcin Czerwinski (@CzerwinsMarcin)
Image from Marcin Czerwinski (@CzerwinsMarcin)
Image from Marcin Czerwinski (@CzerwinsMarcin)
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One more publication to show how versatile Janus lectins can be! Delighted to be a part of Janus's journey and congratulations to everyone involved! doi.org/10.1016/j.csbj.2022.…
Image from Lina Siukstaite (@LSiukstaite)
Simona Notova (@NotovaSimona) profile pictureSimona Notova@NotovaSimona16 Nov 2022
Happy to share our final publication sciencedirect.com/science/ar… where engineered Janus lectins become nowadays a versatile tool 🔧 of synthetic biology. Thanks to all people who put hard effort in this work @AnneImberty @LSiukstaite @VenaFederica Francesca @synBIOcarb
Image from Simona Notova (@NotovaSimona)
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Our scientific committee members Carole Creuzenet, @ElisaTelisa, @DrGlycoBen and Carsten Kettner cordially invite you to save the date of the Beilstein Glyco-Bioinformatics Symposium: 📅 June 20-22, 2023. 🔗 beilstein-institut.de/en/sym… #BeilsteinGlyco2023 #GlycoTime #Glycoscience
Image from Beilstein-Institut @beilstein-institut.bsky.social (@BeilsteinInst)
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From now on, I am officially Dr. rer. nat.! I am grateful to so many people involved in this journey - Prof. Winfried Romer, @AnneImberty @synBIOcarb @UniFreiburg @BIOSSFreiburg and many others!
Image from Lina Siukstaite (@LSiukstaite)
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#glycotime @LSiukstaite +others revealed the big therapeutic potential of lectin-based CARs by developing Gb3-binding lectin-CARs with target-specific cytotoxicity against Burkitt's lymphoma & solid tumor cells (colorectal & triple-negative breast cancer)! bit.ly/3SEpEJv
Image from Ashraf Saad, bridging Glycobiology and Oncology! (@AsAshraf123321)
Image from Ashraf Saad, bridging Glycobiology and Oncology! (@AsAshraf123321)
Image from Ashraf Saad, bridging Glycobiology and Oncology! (@AsAshraf123321)
Image from Ashraf Saad, bridging Glycobiology and Oncology! (@AsAshraf123321)
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Our new paper is out! Take a look at how lectin-CAR T cells efficiently target solid tumour cell lines and more! Warm congratulations to Valeria and everyone involved @LabMinguet @synBIOcarb @BIOSSFreiburg rdcu.be/cVx5V
Image from Lina Siukstaite (@LSiukstaite)
Image from Lina Siukstaite (@LSiukstaite)
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Choanoflagellate lectin SaroL-1 binds to cancer-related α-galactosylated epitopes and can be toxic to cancer cells through a pore-formation mechanism. @synbiocarb @GlycomicsExpasy @NotovaSimona @FBonnardBioInfo @AnneImberty @OgawaEm @LSiukstaite nature.com/articles/s42003-0…
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Happy to be a part of the SaroL1 journey, and today is finally out! Huge congratulations to @NotovaSimona, @AnneImberty, and the others involved!
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Lina Siukstaite retweeted
synBIOcarb (@synBIOcarb) profile picture
synBIOcarb@synBIOcarb29 Mar 2022
2 sweets sides of Janus lectin with our amazing @LSiukstaite @UniFreiburg in full swing at our final conference with @COSTprogramme. Excellent work Lina! @NanoProbes @MSCActions
Image from synBIOcarb (@synBIOcarb)
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Sahara sand over Freiburg. #nofilter
Image from Ralf Reski 🇩🇪🇪🇺 (@ReskiLab)
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A terrible war against Ukraine started with impact on Europe and the world. Ukraine is fighting for their freedom and actually for security for the whole Europe. They need your support now! Follow the link to #StandWithUkraine Please RT! bank.gov.ua/en/news/all/nats…
Image from Andrey Klymchenko 🇺🇦 (@aklymchenko)
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