Research lab at McMaster University examining diet-microbe interactions. More info on our research at https://xitter.cf/t.co/nStxlM9Pyz
Joined April 2023
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Excited to share our new study in Cell Host & Microbe!
We show that bacteria in human saliva and the small intestine can metabolize peanut allergens, reducing IgE binding and anaphylaxis.
Patients with higher peanut tolerance harbor more of these microbes. 1/2
Microbiota impact peanut allergy
Saliva & jejunum harbor peanut-degrading bacteria(Rothia) that metabolize immunodominant PN allergens. Mice colonized w/Rothia show ⬇️anaphylaxis & allergic patients w/better PN tolerance have ⬆️abundance of these bacteria
cell.com/cell-host-microbe/f…
Caminero Lab retweeted
📑 Dietary tryptophan restores microbiota-dependent AhR activation and reduces colitis severity, highlighting a potential diet-microbe approach for IBD management.
🔗 ow.ly/NtGC50ZHKnU
👨⚕️ @LabCaminero @LiamERondeau
🏷️ #IBD #GITwitter
Great collaboration between researchers at @Farncombe_GI, @McMasterU @AlbertoCaminer7 @LiamERondeau @BrunaBLuz and co-led by @R_JimenezSaiz 2/2
Caminero Lab retweeted
Microbiota impact peanut allergy
Saliva & jejunum harbor peanut-degrading bacteria(Rothia) that metabolize immunodominant PN allergens. Mice colonized w/Rothia show ⬇️anaphylaxis & allergic patients w/better PN tolerance have ⬆️abundance of these bacteria
cell.com/cell-host-microbe/f…
Caminero Lab retweeted
Congrats to Dr. @LiamERondeau from @LabCaminero for winning the Junior Investigator Award! 🦠
Tryptophan is an essential amino acid found in protein-rich foods and cruciferous vegetables 🥦. Dr. Rondeau highlighted the protective role of microbial tryptophan metabolism in mouse models of IBD, with potential applications in dietary interventions in IBD care.
#IBDMinds2025
Marching for gut health, microbes, and a cure! Great morning with @Farncombe_GI friends at the #GutsyWalk to support #IBDResearch and @getgutsycanada
Caminero Lab retweeted
Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis @R_JimenezSaiz @LiamERondeau @Elisaaasm @cam
In this #preprint, we demonstrate that #oral #bacteria can break down food #allergens, potentially influencing their systemic absorption, #IgE recognition, and allergic reactions—including #anaphylaxis.
@Elisaaasm @LiamERondeau @AlbertoCaminer7
biorxiv.org/content/10.1101/…
🧪NEW PAPER ALERT🧪
Check out our paper in Gut Microbes that sheds light on the role of proteolytic bacteria in inciting inflammation during #colitis, led by @LiamERondeau, the lab's first grad student @FarncombeGI @McMasterU #IBD
Check it out here👇
tandfonline.com/doi/full/10.…
(⅕)
Using gnotobiotic and conventional mouse models, we demonstrate that proteolytic microbes that activate PAR2 expand during inflammation, thus worsening colitis through a PAR2-mediated feedback loop. (⅘)
These findings highlight the potential of targeting microbial proteolytic activity or PAR2 signaling to alleviate inflammation in IBD patients. #IBDResearch #Microbiome #GutHealth @VerduLab @BrunaBLuz (5/5)
Caminero Lab retweeted
We were pleased to welcome @FilomenaTassi and @SoniaLiberal today for a tour of the clinical and research facilities at the Farncombe Family Digestive Health Research Institute (@Farncombe_GI). @VerduLab @McMasterU
ALT Filomena Tassi and Sonia Sidhu standing in front of the Farncombe Farncombe Family Digestive Health Research Institute with Farncombe faculty and members.
Caminero Lab retweeted
Great presentation by Alberto at the Basic Science Symposium on GI disease and metabolic health @cddw_clm @AlbertoCaminer7
Caminero Lab retweeted
Outstanding CAG @CanGastroAssn prize presentations by postdocs @JulienPujo from @Bercik_Collins and Bruna Barbosa from @LabCaminero @McMasterU @FFDHRI at the #CDDWCLM2024 @cddw_clm
Caminero Lab retweeted
We found Waldo at our Farncombe journal club's Halloween event / team building session where we discussed the consequences of academic dishonesty and data manipulation #spookyscience
Caminero Lab retweeted
Beautiful day for the #gutsywalk in Hamilton! There's still time to donate to support Crohn's and Colitis Canada @getgutsycanada @GutsyWalk @getgutsyhamiltn
Caminero Lab retweeted
Check out our bake sale in support of the Crohn's and Colitis Canada #GUTSYWALK
Where: McMaster HSC 3rd floor atrium, blue section
When: Tues May 31st 10am
Why: To support those living with #IBD
Lots of yummy treats and coffee ☕️🍪🧁
@getgutsycanada @GutsyWalk @machealthsci
