ChabuY (@LabChabu) header
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Interested in the molecular logic that hard-wires robustness into tissue growth programs, and how tumors exploit this logic to survive therapeutic pressure.

Joined January 2018
Photo by ChabuY (@LabChabu)Photo by ChabuY (@LabChabu)Photo by ChabuY (@LabChabu)Photo by ChabuY (@LabChabu)Photo by ChabuY (@LabChabu)
ChabuY retweeted
The Chabu Lab (Chabu-Lab.org) is hiring a Postdoctoral Fellow or Research Specialist to work on our microbial cancer therapeutic platforms in mouse models of pancreatic cancer. Interested? Send CV to [email protected]. #postdocjobs, #tumorimmunology, #PDAC
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Landmark pancreatic cancer drug shows potential against lung cancer too. In a small clinical trial of the drug daraxonrasib (Rasonque), tumours shrank in more than 30% of participants with the most common form of lung cancer, non-small-cell lung cancer. Each participant had a tumour-promoting mutation in a member of the RASfamily of proteins, and had previously tried other therapies.’ nature.com/articles/d41586-0…’
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A 17-year-old just built a mind-controlled prosthetic arm for $300. Yes, $300. For something that usually costs $450,000. Let that hit you. A teenager, working from home, used AI, cheap materials, and 23,000 lines of code to build a device that reads brain signals without surgery, without implants, and without a $450K price tag. This is not a feel-good story. It’s a warning shot. How can a high school student build something 1,500× cheaper than the industry standard? What does that say about innovation? About pricing? About who gets access to life-changing technology? Of course, medical prosthetics are expensive for real reasons: materials, testing, regulation, customization. But let’s be honest — not all of that justifies a half-million-dollar price. This story exposes a simple truth: The future of accessibility won’t come from the system. It will come from the outsiders who dare to challenge it. If a 17-year-old can match top-tier prosthetics for a fraction of the cost… why aren’t these solutions available to the millions who need them? What do you think — breakthrough moment or the start of a bigger revolution? #AI #Innovation #Healthcare #Accessibility #FutureOfTech
Readers added context they thought people might want to know
「脳波で動く義手」ではなく「脳波とモーションセンサで動く義手」である点に留意が必要です。 また、現時点で探索的研究段階であり単純に既存の義手と価格面で比較することはできない点にも留意が必要です。 義手の作者の2025年の論文 pubmed.ncbi.nlm.nih.gov/39854835/
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These great research institutions in red states are slated to lose about $1B in NIH research dollars
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The indiscriminate and ill-conceived slashing of indirects by the @NIH yesterday must be amended if want to restore America’s leadership role biomedical research. 15% simply isn’t enough for institutions to provide the basic infrastructure needed to run a successful lab. I say this as someone who has been and remains deeply critical of the NIH, its funding system and of the ways universities are structured and spend money. We would all benefit from a genuine reexamination of how and to what @NIH funds are allocated, and I remain optimistic that once the dust settles and new NIH leadership is in place that this is what will happen and this hack job by people who don’t understand or care about research will be forgotten. And I’m sorry but I can’t help but laugh at the people who are demanding a full-throated defense of the current indirect levels. Nearly every PI I’ve known for my entire career has complained about excessive indirect rates. This is mostly because, despite their importance, even most PIs haven’t bothered to actually understand them, and because they don’t FEEL that universities are actually spending the money to support their research. Whether they are or not nobody really knows because in the typically Byzantine maze of university budgets it’s often very hard to figure out. There are also lots of actual shenanigans that go on especially at places with the highest indirect rates to use funds to build out the institution and increase its power rather than to directly support funded research projects. And anyone who says administrative bloat at universities isn’t real and partially fueled by indirects is either blind or part of the bloat. So let’s get organized to have an actual constructive response to this firebomb. Scientists need to advocate for what is best for research - and we have to do it ourselves because the institutions that claim to represent us - universities and scientific societies in particular - have their own goals that often do not align with ours. We also have to remember that grants are not an entitlement. We are not owed anything. If we want to continue benefiting from the public support we have always enjoyed, we have to show the public and their representatives - even ones we might not always agree with - that we’re spending their money wisely.
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💪New research led by @LorenaBenedet15 @JLS_Lab shows that subcellular structures similar to those that propagate signals that make muscles contract are also responsible for transmitting signals in the brain that may facilitate learning & memory🧠 🔗 janelia.org/news/from-muscle…
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Meet the shortlisted candidates for the 2023 Nature Awards for Inspiring Women in Science

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The first #Drosophila Spanish meeting #DrosoSpain2024 will take place in Alicante in March 2024 #SAVETHEDATE
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You nailed it, Finally! Congratulations @NadsPatterson on your well-earned doctorate. Your accomplishment is outstanding! You have made the Chabu Lab the proudest ever. Keep soaring. Keep shinning. I am very proud of you my mentor.
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ChabuY retweeted
Cancer researchers at the AACR Annual Meeting 2023 and a conference earlier this year, focus on targeting KRAS, a protein once viewed as "undruggable." Learn more in #AACRStories: aacr.org/about-the-aacr/news… #AACR23 @OncoAlert
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Time to submit abstracts for the European Fly Meeting, in October in Lyon! You will hear about amazing science across a broad spectrum of disciplines in a gorgeous city that has delectable food. Trust us, you want to be there!!! #Fly #FOMO @EDRC2023 tinyurl.com/4u5kuuxa
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More thoughts on the demise of disruptive science. Take Fred Sanger, 2x Nobel Prize winner. Sydney Brenner wrote about him in an obituary that multiple times in Fred's career, he went 10+ years without publishing as he was working on 'disruptive' science. science.org/doi/full/10.1126…
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New Nature paper provides evidence that science has become less innovative since the 1950s. The authors suggest reversing the trend by: 1. reading widely, 2. focusing less on quantity of papers, & more on research quality, 3. taking year-long sabbaticals. nature.com/articles/s41586-0…
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I’ve been silent on twitter because it has been a rough semester. Worst betrayal of trust I have ever had with a graduate student. But my middle son knitted me this hat, and when I wear it, I start to feel like things might be okay again. #magichat
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Please RT: The IBDM is seeking new group leaders. Your chance to contribute to shaping tomorrow’s research in the field of developmental biology in the south of France 👇🏻
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Congratulations Roy. So well deserved.
Congratulations to .@DrRoyHerbstYale honored today by @IASLC during their annual meeting #TTLC22 for his years of dedication and service to the organization and community. @SmilowCancer @YaleMed @YNHH #lcsm yalecancercenter.org/news-ar…
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ChabuY retweeted
Nature research paper: Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias go.nature.com/3BaoldI
How Ras signaling really works
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The conceptual link between Aim 2 and Aim1
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[PLEASE RT] #Vosshalllab is hiring!! Come join our diverse and vibrant community @RockefellerUniv as a research technician: bit.ly/2Yo4Z5l **you don't have to be bitten by mosquitoes, I promise