The Jacks Lab, established in 1992. Koch Institute for Integrative Cancer Research at MIT. Cancer genetics. GEMMs. Tumor immunology. Run by lab members.
Cambridge, MA
Joined June 2021
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Jacks Lab retweeted
Excited to announce the Yang lab officially opens at @Columbia University. We are interested in developing innovative single cell recording technologies to study tumor evolution and cancer plasticity. We are hiring motivated postdocs & students, please RT dianyanglab.com/
Jacks Lab retweeted
Out today, with @LabJacks, @isidrolauscher, @fran_muyas, we used new mouse models of spontaneous lung and colon cancer to delineate a mechanism for why many patients with DNA mismatch repair deficient (MMRd) tumors may not respond to immunotherapy 🧵1/11
nature.com/articles/s41588-0…
Jacks Lab retweeted
A prime editor mouse to model a broad spectrum of somatic mutations in vivo go.nature.com/3Bk8fz4
Jacks Lab retweeted
Tyler Jacks’ Keynote Lecture: “Genetic engineering meets tumor immunology: Lessons from mouse models of cancer” @LabJacks #eacrImmunoOncology
Jacks Lab retweeted
Tyler Jacks from @kochinstitute @MIT presenting eloquent vignettes (called tapas while @EACRnews #eacrImmunoOncology in Spain) on genetic engineering approaches in mice that have revealed profound insights into immuno-oncology and novel targets.
Jacks Lab retweeted
Congratulations to Tyler Jacks, recipient of the Ernst W. Bertner Memorial Award!
Professor Jacks will be giving his award lecture and presentation at 2022 Leading Edge Symposium at MD Anderson on Thurs. November 17.
mdanderson.org/research/rese…
ALT Tyler Jacks
Jacks Lab retweeted
We engineer peptides to sense targeted enzyme activity in cancer tissue! Published in @NatureComms:
✅ nanoscale + noninvasive
✅ high-fidelity cancer monitoring
✅ multi-scale resolution sensing
from single cell 🦠 - to tissue 🫁 - to whole organism🧍
👉nature.com/articles/s41467-0…
Jacks Lab retweeted
I am beyond excited to share our paper, 'Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type II (AT2) organoid platform', now out in @GenesDev. genesdev.cshlp.org/content/3… 🧵(1/10) @LabJacks @kochinstitute @MIT
Jacks Lab retweeted
The Burger Lab is officially open and recruiting! Join us at the beautiful OHSU Knight Cancer Institute on the waterfront of fun and wonderfully quirky Portland. If you are interested in T cell biology and immunotherapy for cancer, we are the group for you! Positions 👇 🙏 RT! 1/
Jacks Lab retweeted
Join us at @Columbia @ColumbiaMPT @ColumbiaCancer! We are looking for research technicians and postdocs to join our team. Please retweet. #CancerEpigenetics #MouseModels
Jacks Lab retweeted
Ludwig scientists helped pioneer modern cancer immunotherapy, developing the MAGE & NY-ESO-1 antigens for such therapies. A trial now underway in the UK is evaluating their utility in a candidate vaccination regimen for lung cancer. bit.ly/38OPxVN #CIM22 #Immune2Cancer
Jacks Lab retweeted
Ludwig @MIT scientists found that certain cancer antigens can monopolize the T cell response in tumors & that vaccinating mice with a subdominant antigen stimulated the generation of potent T cells & shrank lung tumors in the mice. bit.ly/3N9ygFH #CIM22 #Immune2Cancer
Jacks Lab retweeted
Just some @LabJacks members having a blast at the @kochinstitute summer symposium! #KIsymposium @KarenKarenoyee
Jacks Lab retweeted
Proud to share my work out today in @Nature interrogating antigen presentation in vivo! We found that physiological context shapes the antigenic repertoire of cancer cells and describe a new tool to uncover tissue and cell type specific antigens in vivo.
nature.com/articles/s41586-0…
Jacks Lab retweeted
Turns out, when you look at the antigens tumor cells *specifically* present in an immune competent context, they have their own story to tell…✨
Brilliant study lead by @ajaeger40, Proteomics led by myself & @RyuhjinAhn with @kochinstitute & @LabJacks.
nature.com/articles/s41586-0… – at Cambridge, MA
Jacks Lab retweeted
Thank you for the generous support @BWFUND! Excited to be in the same class with #WillFreedPastor in @LabJacks. Congrats to everyone!
The Burroughs Wellcome Fund is pleased to announce the recipients of the 2022 Career Award for Medical Scientists buff.ly/3GGFRZL
#bwfcams #bwfrtp
Jacks Lab retweeted
We’re excited by the progress being made against #pancreaticcancer such as research into #KRAS like that cited in this @nytimes story. + work we’re funding w @DrLizJaffee & @LabJacks with @break_cancer
The need is urgent!
nytimes.com/2022/06/01/healt… – at Brooklyn, NY
Jacks Lab retweeted
Congratulations to @LabJacks alum Daniel Zhang on being awarded a Fulbright Fellowship!
Zhang plans to develop an organoid co-culture system to study malignant rhabdoid tumors, and then use this platform to screen for new therapeutic vulnerabilities. news.mit.edu/2022/mit-fulbri…
ALT Daniel Zhang
Jacks Lab retweeted
An inspiring 30 year reunion of the @LabJacks family at @kochinstitute! Thanks to the organizers @TuomasTammela @DKirschMDPhD @AttardiLaura @teixeirajudy1 for putting together such an amazing meeting. Looking forward to the next anniversary!
Back from an amazing weekend with @LabJacks members and alumni celebrating 30 years of the Jacks Lab. This is a very special group of people, inspired by one of the most influential mentors of our time. A big honor to co-organize with @AttardiLaura @DKirschMDPhD @teixeirajudy1