@LabMears

We study mitochondrial dynamics using structural, functional, and cellular methods.

 Cleveland, OH
pharmacology.case.edu/department/faculty/primary/pages/mears.aspx
Joined June 2018
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Very grateful to @LabMears for this fantastic summary of our work identifying a new mitochondrial cristae shaping protein in @CurrentBiology. Be sure to give it a read and check out our paper if you missed it! cell.com/current-biology/ful…
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It is with great sadness that we announce the recent passing of Emeritus Fellow Professor Stuart Ferguson. Stuart will be very much missed by all seh.ox.ac.uk/news/hall-remem…
Professor Stuart Ferguson

ALT Professor Stuart Ferguson

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Happy to share new structure of the Drp1 lattice on a membrane. Great collaboration with @sstaggal using RASTR method. Ray and @KristyRochon did an amazing job pulling this together. biorxiv.org/content/10.1101/…

The Structure of the Drp1 Lattice on Membrane

Mitochondrial health relies on the membrane fission mediated by dynamin-related protein 1 (Drp1). Previous structural studies of Drp1 on remodeled membranes were hampered by heterogeneity, leaving a...

biorxiv.org
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Replying to @LabFriedman @UTSWGradSchool @CellUtsw
Congratulations to you both! Love the art.
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Replying to @DiFeoLab
That is awesome! Congratulations Rita!
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The Vaziri-Gohar Lab is hiring a postdoc. This is a great postdoctoral training opportunity for individuals interested in Cancer Metabolism. Please send your inquiries directly to [email protected]. @LoyolaChicago @LoyolaHealth @CancerResearch @NatureCancer #PancreaticCancer
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Sad to have missed it (had to head out early today), but I know Yuli always does a great job presenting her science.
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Replying to @RuthKeri2
Thanks Ruth
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Replying to @_Blake_Hill @DTaylorLab
Thanks Blake.
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Kristy's Drp1 dimer structure is officially out! Yes, the mitochondrial fission protein is very dynamic, and novel conformations regulate assembly and function. Thanks to @DTaylorLab, Yu and Ramachandran Labs for your contributions. rdcu.be/dywTF
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Anelise did a great job yesterday. Lots of visitors and interest in her work.
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Special treat to hear from Jenny as she receives the Katz Award in the Membrane Fission, Fusion and Traffic subgroup at #BPS2024.
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Always fun being back at #BPS2024. Be sure to visit Anelise and Yuli on Sunday and Wednesday…
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Replying to @KristyRochon
@KristyRochon did a fantastic job with her thesis defense today. Big congratulations and celebration for DR. Rochon 🍾🎉
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Replying to @ali_vazirigohar @LoyolaChicago @LoyolaHealth
Congrats to you both!
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Big congrats to Brianna on a successful thesis defense! Couldn’t be prouder.
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Replying to @UMassChan @UMassChan_BMB @ASCBiology
Congratulations!
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Replying to @khalid68322059
Congratulations Khalid!
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Great collaborative work with Ramachandran and Yu labs, as well as @DTaylorLab
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Happy to share latest from @KristyRochon highlighting structural changes that regulate mitochondrial fission. Structural Basis for Regulated Assembly of the Mitochondrial Fission GTPase Drp1 biorxiv.org/content/10.1101/…

Structural Basis for Regulated Assembly of the Mitochondrial Fission GTPase Drp1

Mitochondrial fission is crucial for distributing cellular energy throughout cells and for isolating damaged regions of the organelle that are targeted for degradation. This multistep process is...

biorxiv.org
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