@SamDasLab1: Inactivating the TN/TX miRNA-degrading enzyme blocks #VSMC stiffness and #aging-associated aortic stiffness in vivo. New target for treating large artery stiffness and #Hypertension.
Addressing the limitation of inability to detect LOX catalytic function associated with diverse disease processes, Wang et al. developed an in situ activity assay by utilizing the reactivity of hydrazides with imines and carbonyls. @LabSanthanamnature.com/articles/s42003-0…