
ALT Non-canonical ubiquitylation mini-series Monday 8th May 2024, 11 am (UK Time) ***Online Only Seminar (via TEAMS)*** Meeting details: Meeting ID: 326 741 698 196 Passcode: Eq28jy Calendar Appointment available at: https://www.ppu.mrc.ac.uk/lectures/bernhard-lechtenberg Teaser: In his presentation, Bernhard will first outline his lab’s recent work on the structure and function of the RBR E3 ubiquitin ligase HOIL-1 and how it helped to define the unifying principles of RBR regulation and catalysis. In the second part, he will present unpublished work on the substrate specificity of HOIL-1 and its ability to ubiquitinate non-canonical substrates such as serine and threonine residues and non-proteinaceous substrates such as sugars.

ALT Chief investigators at the Australian Centre for Targeted Therapeutics: Professor John Silke (WEHI), Professor Guillaume Lessene (WEHI), Professor Michelle Haber (Children’s Cancer Institute), Professor David Komander (WEHI), Professor Susan Charman (Monash University), Dr Rebecca Feltham (WEHI), Dr Bernhard Lechtenberg (WEHI).































