News and research from microbial sciences at the University of Leicester. Microbiology, microbial genetics, and immunology.
University of Leicester
Joined October 2015
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Leicester Micro retweeted
🚨I did a science!🚨 I was lucky enough to help write a chapter on "Viruses" for this monograph on the lung microbiome along with @MarthaClokie and Will Flight. So have a look, there is some phagey-ness inside 😃
So this is now available erspublications.blogspot.com… an enormous effort from our authors and reviewers and an attempt to gather together the strands of lung microbiome research, particularly for ERS members.
Leicester Micro retweeted
We have a BBSRC post doc position available jobs.le.ac.uk/vacancies/vaca… following on from our characterisation of a novel copper resistance mechanism (CopB/X CopL) associated with the SCCmec in S. aureus USA300. 10.1111/1462-2920.14088
Great opportunity to work on a multi-disciplinary PhD project here at Leicester #AMR #nanotechnology #phdchat
Exciting PhD position on functionalised nanodiamonds for antimicrobial resistance application. With Prof Marco Oggioni see :
www2.le.ac.uk/colleges/scien…
Leicester Micro retweeted
Our manuscript looking at the contribution of the Alkylquinolone Quorum-Sensing system to the interaction of P. aeruginosa with Bronchial Epithelial Cells is out now. Good times!! Very proud of this work. @miguelcamarauk @UoNresearch @UoNLifeSci frontiersin.org/articles/10.…
Leicester Micro retweeted
Technician job in my lab! Looking for temp, p/t support to help my team to push a project to completion in Jan-Mar. Could be ideal for someone waiting for a PhD viva, or an existing p/t tech who wants some extra hours n the new year: unitemps.com/Search/JobDetai…
Leicester Micro retweeted
PhD opportunity at Leicester-MRC Harwell-Nottingham. Look out for our project together with Chris Bayliss and Derek Hood on "Impact of hypermutable sequences on microbial elucitation and evasion of host immune responses". www2.le.ac.uk/research-degre…
Leicester Micro retweeted
A new paper from our group describes a new #vaccine strategy against #pneumococcus. A genetically enginerened E. coli strain was used to both produce and conjugate carrier proteins and glycan. The formulated vaccine resulted to be protective both against pneumonia and meningitis.
Pneumococcal #vaccines: evaluation of a multivalent pneumococcal glycoconjugate vaccine
go.nature.com/2yHidL3
Great paper from @Hasanyesilkayaa at Leicester! #pneumococcus
Pneumococcal galactose catabolism is controlled by multiple regulators acting on pyruvate formate lyase. dlvr.it/QqqzBB
Leicester Micro retweeted
The pneumococcal surface proteins PspA and PspC sequester host C4 binding protein to inactivate complement C4b on the bacterial surface iai.asm.org/content/early/20…
Leicester Micro retweeted
Fantastic work from @MartaZapotoczna and our great collaborators at Newcastle, U Penn, @Infection_StAnd , @Leicester_Micro & Scottish MRSA Reference Lab #copper #MRSA
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Paper from the Bayliss group - 'PhasomeIt: an 'omics' approach to cataloguing the potential breadth of phase variation in the genus Campylobacter' out in #MGen @MicrobioSoc @Joewanford @Neisseriaspanin @JackAidley . Great collaboration with @sheppard_lab - goo.gl/FnMNdN
Leicester Micro retweeted
Now available as a full article! An investigation of how the phase variable tract of nadA could be used as a surrogate for prediction of Bexsero coverage, looks pretty good too #mrf #meningitis jcm.asm.org/content/56/9/e00…
Great model from @peppeercoli and co, for the translation of pneumococcal research to a human-comparable model, and also for the reduction of exp animals in sepsis research! Out in #preprint in ALTEX @NC3Rs @jhucaat #sepsis #pneumococcus #pathogenesis
If you are interested in bacterial infections and replacement of lab animal experimentation #3Rs, have a look at our innovative ex vivo model of bacterial sepsis using pig spleens retrieved from the abattoir @Joewanford @mr_oggioni #pneumococcus #sepsis tinyurl.com/ybk5cy7j
Great model from @peppeercoli and co, for the translation of pneumococcal research in mice to a human-like system, and also the reduction of exp animals in sepsis research! Out in #preprint in ALTEX - tinyurl.com/ybk5cy7j @NC3Rs
@jhucaat #sepsis #pneumococcus #pathogenesis
If you are interested in bacterial infections and replacement of lab animal experimentation #3Rs, have a look at our innovative ex vivo model of bacterial sepsis using pig spleens retrieved from the abattoir @Joewanford @mr_oggioni #pneumococcus #sepsis tinyurl.com/ybk5cy7j
Just out - 'Integrase-Controlled Excision of Metal-Resistance Genomic Islands in Acinetobacter baumannii' from the Oggioni group! Congrats Zaaima and co #AMR mdpi.com/2073-4425/9/7/366
Congratulations to Zaaima for this great paper looking at how integrase activity excises much larger sections of DNA from genomic islands than previously thought! So pleased to have been able to contribute to this work mdpi.com/2073-4425/9/7/366
Great work from the Bayliss group showing that phase variable gene expression can affect vaccine coverage estimates teapawt.net/LeicesterMID/status/10…
Phase Variation of NadA in Invasive Neisseria meningitidis Isolates Impacts on Coverage Estimates for 4C-MenB, a MenB vaccine. dlvr.it/QYvjL5
Leicester Micro retweeted
Researchers at @Leicester_Micro and @M_R_F have developed a new test to find out if meningitis infection could have been prevented by vaccination: microb.io/2JXW8PS
'Research finds new way to determine protection of Men B vaccine against different strains' www2.le.ac.uk/offices/press/… @UoLOutreach @LeicesterMID #vaccines #Meningitis
New paper from the Bayliss lab out in @PLOSONE - 'Clustered intergenic region sequences as predictors of fHbp expression patterns and for assessing N. meningitidis strain coverage by meningococcal vaccines.' #vaccines #meningitis
goo.gl/HSyGh6