ID/AMS PharmD @MercyCR 🦠 PGY2 ID @AbbottHospital 💊 Class of 2020 @UIowa ⚔️ Antibiotic Defender. Views are my own.
Cedar Rapids, IA
Joined May 2021
- Tweets301
- Following320
- Followers296
- Likes1.1K
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
“Unfortunately, I think the problem of antibiotic resistance is going to get worse before it gets better. I worry that my grandchildren won’t have access to effective #antibiotics.”
@JasonGNewland on the urgent need for new antibiotics. #USAAW24
pew.org/4fkfOYQ
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
"Based on available evidence from 30 RCTs....topical estrogen is effective at reducing recurrent UTIs in postmenopausal women."
WHY IS NOT EVERY POSTMENOPAUSAL WOMEN ON THE PLANET OFFERED VAGINAL ESTROGEN FOR UTI PREVENTION??!!
30 Randomized controlled trials! THIRTY!
This consensus statement creates a clinical guideline for the diagnosis and management of UTIs that addresses the gap between the evidence and recommendation strength. ja.ma/3UBBW90 @bradspellberg
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
Proposed assessment framework for patients with suspected UTI who live in long-term care facilities from @Wiki_Guidelines
⭐No more urinalysis or urine culture simply for altered mental state/smelly urine/cloudy urine
⭐If other causes of fever are present, skip the urine tests
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
We are proud to present the next @Wiki_Guidelines on UTI; providing the first comprehensive review of literature in the immense area of UTI in over FOURTEEN YEARS. Thanks to everyone who contributed. We truly hope this will make a difference in the care of patients!!!
🔥🔥Just published🔥🔥
Our NEW @Wiki_Guidelines @JAMANetworkOpen
A stellar cast of auth🌟rs @zacroBID @amenalor @BradSpellberg @DrToddLee @DrEmilyMcD
Guidelines for the Prevention Diagnosis,and Management of Urinary Tract Infections in Pediatrics& Adults
jamanetwork.com/journals/jam…
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
We are delighted to announce the publication of UTI WikiGuideline in JAMA Network Open. Thank you to the 54 experts from 12 countries for drafting. Special thanks to @zacroBID and @amenalor for leading the effort.
jamanetwork.com/searchresult…
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
🏀 If you’ve ever wanted to throw a keyboard in a trash can to prevent an unnecessary urine culture from being ordered, this one is for you! 🗑️
Ps @C_Deri6 you are an absolute star 🤩
#USAAW23 #WAAW2023 #BeAntibioticsAware
For today's grand finale, we drew inspiration from Dikembe Mutombo for some new #antimicrobialstewardship strategies.
*We can neither confirm nor deny that antimicrobial stewardship will save you 15% on car insurance.*
#USAAW23 #WAAW2023 #WAAW
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
Things I do not care about when discussing UA's and urine cultures:
❌Pyuria/Leuk esterase +
❌Nitrites
❌Bacteria on microscopy
❌Growth of bacteria on cultures
Things I do care about:
✅SYMPTOMS
Everything else is just asymptomatic bacteriuria! #IDTwitter #MedTwitter
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
Updated guidance from this week’s @CDCgov @RealTimeCOVID19 Clinician Outreach call regarding vaccines for respiratory viral infections as we head into the fall! 💉😷🍂🍁
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
Faster is better. 📄 Nice work!
academic.oup.com/ajhp/advanc… in @AJHPOfficial
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
“The commonly used cutoff of 10 leukocytes/µL had a poor specificity (36%) and a sensitivity of 100%.”
academic.oup.com/cid/article… in @CIDJournal
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
For non ID colleagues and ID ICYMI
these are the most important updates that you must know about the new CLSI "M100-Ed33"!
Updated Aminoglycoside Breakpoints for Enterobacterales & Pseudomonas aeruginosa
Background & Reasons for the Changes!
🌟Bookmark🌟
clsi.org/about/blog/ast-news…
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
Contaminant teapawt.net/shouldhaveapet/status/…
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
We (or YOU, really!) have thoughts. Some highlights in diagnostic stewardship (removing UA/cx from order sets), ER interventions on following up on UA cx, and a "mindful pause" on diagnosis.... #ASPchat
doi.org/10.1017/ash.2023.117
doi.org/10.1017/ash.2023.166
doi.org/10.1017/ash.2022.343
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
Long-acting cabotegravir-rilpivirine (CAB-RPV) is the biggest advance in HIV therapeutics in years.
Here's a brief explainer why, and a killer classic movie clip.
(Next up -- the limitations of this groundbreaking treatment, because there are plenty.) blogs.jwatch.org/hiv-id-obse…
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
Conference abstracts accepted, but no publications?
It's a common story for residency research projects.
As someone who'd experienced it 6 times...
these are the reasons why many residency projects go NOWHERE.
Brace yourself, because it's time for some tough love.
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
You can help free up nursing time by converting IV antibiotics to PO. Save 1 hr by changing an IV q8h antibiotic to PO!
Consider a point prevalence analysis at your hospital to see how much time could be saved if 10% of courses were changed to PO!
#ISAS23 @jpogue1 #IDTwitter – at Illinois, USA
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
With the latest CLSI breakpoints, tobramycin is the only reliable aminoglycoside for Pseudomonas if you ever need one (Susceptible: MIC ≤1)
Amikacin: can still be used for UTI (Susceptible: MIC ≤ 16)
Gentamicin: RIP ☠️
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
Cellulitis is a clinical diagnosis with several mimics and no gold standard diagnostic criteria. Misdiagnosis is common?!
🆕️⚡️⚡️Systematic Review & Meta-analysis
The mean proportion misdiagnosed was 41% (95% CI 28 to 56% for random effects model. Ouch!
link.springer.com/article/10…
Lexi Thumann, PharmD, BCIDP, AAHIVP retweeted
🔥BREAKING🔥
US FDA approved Xacduro (sulbactam durlobactam for injection), a new treatment for hospital-acquired bacterial pneumonia &ventilator-associated bacterial pneumonia caused by Acinetobacter baumannii-calcoaceticus complex
#IDTwitter
fda.gov/news-events/press-an…
