@LichmanLab

Lab working on plant natural product biosynthesis from enzymes to evolution

 University of York
lichmanlab.weebly.com/
Joined December 2018
  • Tweets528
  • Following407
  • Followers1K
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Check out our new opinion paper on plant biosynthetic pathway discovery, spearheaded by #FeliciaWolters, @elena_delpup et al.
Elena Del Pup@elena_delpup11 Nov 2024
How do we pair omics to decode the diversity of 🌱plant specialized metabolism? In our latest paper, we present a perspective on how paired omics can support a collaborative effort to characterise the plant metabolome. @marnixmedema @jjjvanderhooft sciencedirect.com/science/ar…
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Liz Rylott@LizRylott7 Nov 2024
Chuffed to bits to be awarded the Milton P. Gordon Award for Excellence in #Phytoremediation at the International Phytotechnology Society's (IPS) annual conference held in Kerala, India; October 22 - 24, 2024. ipc18.uoc.ac.in/
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Please like, reshare and donate if you can. Today and tomorrow it's Giving Day at @UniOfYork! GenRes is part of this charity event, and we need your help to to raise as much money as we can for future scientists from all backgrounds. Share and donate at spsr.me/c9c4
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A blueprint of the diatom pyrenoid reveals a Rubisco encapsulating protein Shell is critical for CO2 fixation. Is it essential for global NPP? Congrats to @OnyouNam,@james_r_barrett,@ItsCarolineMck,@JNB_lab + great collab with @DemulderManon,@bengeliscious.doi.org/10.1016/j.cell.2024.…
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Exciting paired omics mining workshop coming up in Wageningen, with international team of teachers @jjjvanderhooft @kate_duncan @Pdorrestein1 @tilmweber @MargheSosio, yours truly and more. Sign up now!!
Justin van der Hooft@jjjvanderhooft6 Sep 2024
🚨You can now apply for the #NPLinker eScience Workshop to be held in March 2025, in Wageningen, the Netherlands! 🚨 😎 The application form is open till the end of October! Link to the form: forms.office.com/e/PsZiktgjv…
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ARIA
@ARIA_research2 Oct 2024
“There are not many times in your life where you have serious resources to realise a scientific vision of your own making.” From the ambition of our Programme Directors to our culture, dive into what makes ARIA, ARIA, in this in-depth piece from @WIRED. link.aria.org.uk/wired-x

Eight Scientists, a Billion Dollars, and the Moonshot Agency Trying to Make Britain Great Again

The Advanced Research and Invention Agency—ARIA—is the UK's answer to Darpa. But can it put the country back on the scientific map?

wired.com
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I'll be sharing past and present research on the biosynthesis of betalains and of wheat phytoalexins in the PhytoChemTalks series. Fri 27th Sept. 12pm EST online. Turn on, tune in... phytochemtalks.github.io/
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Cell@CellCellPress14 Sep 2024
Now online! A developmental gradient reveals biosynthetic pathways to eukaryotic toxins in monocot geophytes dlvr.it/TDDhQ3

A developmental gradient reveals biosynthetic pathways to eukaryotic toxins in monocot geophytes

The biosynthetic pathways in plants that yield important and clinically relevant toxins are complicated and difficult to elucidate. Through combined metabolomics, the biosynthetic pathways of a...

cell.com
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We're excited to share the work led by Dr. @PeterWinegar on the complete biosynthesis of verazine. This accomplishment marks the #1st heterologous steroidal alkaloid produced in engineered yeast, unlocking future drug development. Congrats, Peter!! 🧬🎉 sciencedirect.com/science/ar…
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Very excited to see this PhD idea finally published as a review @NatProdReports. We classified all MIA oligomers (~1000) through their chemical logic assembly. 3 years of efforts. The structures were submitted @TheLOTUSInitia1 kudos @Adafede pubs.rsc.org/en/content/arti…

Structural diversity and chemical logic underlying the assembly of monoterpene indole alkaloids...

Covering: up to 2024 This review aims to draw a parallel between all known oligomers of monoterpene indole alkaloids (MIAs) by illustrating the chemical lo

pubs.rsc.org
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Tom Ellis@ProfTomEllis8 Sep 2024
🚨My department here in London 🇬🇧 has an open faculty position in at any level, looking for a PI in food-related bioengineering and synthetic biology. This is a really exciting opportunity that closes on Sept 22. DM me if you want to apply! Please RT 🔁 imperial.ac.uk/jobs/search-j…

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

imperial.ac.uk
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Cobus Smit@CobusSmit2119 Aug 2024
Happy to share our chromosome level genomes for Drepanocaryum sewerzowii and Marmoritis complanata, two new assemblies within the Nepetinae and related to catnip. academic.oup.com/g3journal/a… @GrantGodden @danieljeffares @LabRat_C @LichmanLab

Pseudomolecule-scale genome assemblies of Drepanocaryum sewerzowii and Marmoritis complanata

Abstract. The Nepetoideae, a subfamily of Lamiaceae (mint family), is rich in aromatic plants, many of which are sought after for their use as flavors and

academic.oup.com
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Do you have experience working with fungi and/or natural product chemistry? I have a 7-month Senior Research Technician job available in my group at @WarwickLifeSci to work alongside a PDRA on developing engineering tools for fungi 🍄🧬💊 warwick-careers.tal.net/vx/l… Please RT
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Giant #PolyketideSynthaseEnzymes in the #biosynthesis of giant marine polyether toxins by @photocyte, @VikShende, Wierzbicki, Pendleton, Watervoot, Auber, Gonzalez, Wisecaver, @BradMoore_SIO @moorelabsio in @ScienceMagazine science.org/doi/10.1126/scie…
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🔓Take a look in our latest issue at this #OpenAccess article by Jonathan Chekan, Roland Kersten & co @ChekanLab @kersten_lab highlighting the chemistry, biosynthesis & function of plant RiPPs 📍@uncg_chem @UMichPharmacy pubs.rsc.org/en/content/arti…

Plant peptides – redefining an area of ribosomally synthesized and post-translationally modified...

Covering 1965 to February 2024 Plants are prolific peptide chemists and are known to make thousands of different peptidic molecules. These peptides vary dr

pubs.rsc.org
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Many specialized metabolite classes have convergently evolved across the plant kingdom. Pleased to share our latest work arguing for why such sporadic evolution has occurred, using cyanogenic glycosides as a case study. @raqueldinamarq1 doi.org/10.1016/j.pbi.2024.1…
Representative chemical structures of core, simple and modified cyanogenic glycosides. Images of corresponding cyanogenic plants are included.

ALT Representative chemical structures of core, simple and modified cyanogenic glycosides. Images of corresponding cyanogenic plants are included.

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🌸🫧🌸🫧🌸🫧🌸🫧🌸🫧🌸🫧🌸🫧🌸 Extremely thrilled to *finally* share our work on saponin biosynthesis in soapwort🧼⚕️🌱 @nchembio @JohnInnesCentre @AnneOsbourn1 🌸🫧🌸🫧🌸🫧🌸🫧🌸🫧🌸🫧🌸🫧🌸 nature.com/articles/s41589-0…

Unlocking saponin biosynthesis in soapwort

Nature Chemical Biology - Soapwort (Saponaria officinalis) is a rich reservoir of triterpenoid glycosides that often have important pharmaceutical, nutraceutical and agronomical potential. Here,...

nature.com
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Let's try something new: I am looking for bioinfo collaborators that know how to analyze DNA methylation, lncRNA and sRNA data, preferably in plants, for time series stress data. The aim is to improve and re-submit this manuscript: biorxiv.org/content/10.1101/…

Multi-omic dissection of ancestral heat stress memory responses in Brachypodium distachyon

Stressful environmental conditions, including heat stress (HS), are a major limiting factor in crop yield. Understanding the molecular mechanisms of plant stress memory and resilience is important...

biorxiv.org
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Are you interested in yeast and synthetic biology??? then we have the perfect spot for you😊. We are hiring a postdoc for a 2-years, to work with yeast, GPCR proteins and biosensors, here at @UCPH_Research. Contact us if you are interested! looking forward to meet you 🥳😊😃
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Expanding chemistry through in vitro and in vivo #biocatalysis by Elijah N. Kissman, Max B. Sosa @maxbsosa, Douglas C. Millar, Edward J. Koleski, Kershanthen Thevasundaram, and Michelle C. Y. Chang @MChangGroup at @UCB_Chemistry @PrincetonChem in @Nature nature.com/articles/s41586-0…
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