@MAndersonUCSF

Professor, University of California, San Francisco Director, Diabetes Center at UCSF @AtUcsf President, Fed of Clinical Immunology Societies @FOCISimmunology

 San Francisco, CA
diabetes.ucsf.edu
Joined March 2020
  • Tweets183
  • Following43
  • Followers637
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LUCKY when one can combine work with friendship. I am very lucky @ucsfhealth w. friends @immunox @UCSFAging & friendly relationships with @UCSF leadership. Excited how this "group of friends" imagined a 2017 dream & very grateful to Bakar family and others to make this reality.
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Mark Anderson retweeted
UC San Francisco@UCSF7 Aug 2024
Early in the pandemic, kids were hospitalized with a mysterious disease, MIS-C. A team led by @DrAaron14 @MAndersonUCSF @czbiohub discovered how mild COVID led to MIS-C, hinting at what might go wrong in autoimmune diseases like #MS. @BCH_InTheNews @stjude tiny.ucsf.edu/ArB6Z7
Two individuals in a laboratory setting, wearing lab coats. The person on the left is wearing a blue lab coat and has a beard, while the person on the right is in a white lab coat with blond hair. They are standing in front of a lab bench scattered with various scientific equipment, smiling towards the camera. Both are wearing identification badges.

ALT Two individuals in a laboratory setting, wearing lab coats. The person on the left is wearing a blue lab coat and has a beard, while the person on the right is in a white lab coat with blond hair. They are standing in front of a lab bench scattered with various scientific equipment, smiling towards the camera. Both are wearing identification badges.

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Scientists Get to the Bottom of COVID’s Worst Pediatric Complication ucsf.edu/news/2024/08/428176…
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Proud of our team that unlocked this terrible complication of COVID-19 in children. @AtUcsf @UCSF @immunox nature.com/articles/s41586-0…

Molecular mimicry in multisystem inflammatory syndrome in children

Nature - A cross-reactive antibody and T cell response is identified in a large portion of patients with multisystem inflammatory syndrome in children.

nature.com
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Congrats to our team in the UCSF Diabetes Center!
Suneil Koliwad@SuneilKoliwad5 Jul 2024
Microglia can be manipulated to impact CNS control of weight gain and glucose control. But what do hypothalamic microglia do? We now explore this in newborn mice, with fascinating results. Congrats to @MValdearcos and our outstanding team! @AtUcsf @NorcUcsf @UCSF
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Insights: @DrCindyMa & @stutangye discuss new study from @MACattackLab (hubs.la/Q02F282T0) that proposes a role for dysregulated IL-22 production by Th17 cells in causing some aspects of immune-mediated skin inflammation in #STAT3GOF syndrome. hubs.la/Q02F26zv0
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Great piece on all of the excitement around Ozempic and GLP-1 agonists. Great job Suneil!
Diabetes Center at UCSF@AtUcsf26 Jun 2024
Weight loss drug article in @UCSF Magazine featuring UCSF Diabetes Center professor and Chief of Endocrinology @SuneilKoliwad magazine.ucsf.edu/weight-los…

Are the New Weight Loss Drugs Too Good to Be True?

The real answer isn’t “yes” or “no.” Here are six things you need to know.

magazine.ucsf.edu
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Honored and thrilled for this recognition
Diabetes Center at UCSF@AtUcsf21 Jun 2024
UCSF Diabetes Center Director Mark Anderson Receives 2024 Cancer Research Institute Coley Award @MAndersonUCSF @CancerResearch diabetes.ucsf.edu/node/1746
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Excited to share new collaborative work on the autoreactome that just came out in JCI jci.org/articles/view/180012
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"Decoding gene regulation with CRISPR perturbations" by @McManus_Lab postdoc Stefan Oberlin published in @NatureBiotech
Nature Biotechnology
@NatureBiotech20 May 2024
Replying to @NatureBiotech
Decoding gene regulation with CRISPR perturbations #NBTNV go.nature.com/3WOWHjb
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Excited to share some new collaborative work with the Kappler lab on how thymic tolerance to insulin is maintained in a model of T1 Diabetes. Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones | PNAS pnas.org/doi/10.1073/pnas.23…
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Excited to be part of a team that identified a rare family with a defect in PDL1 that has a strong link to type 1 diabetes and other immune dysregulation. rupress.org/jem/article/221/…

Human inherited PD-L1 deficiency is clinically and immunologically less severe than PD-1 deficiency

Johnson, Ogishi, and Domingo-Vila et al. describe two siblings with inherited PD-L1 deficiency. Human PD-L1 deficiency underlies early-onset T1D, like PD-1

rupress.org
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Mark Anderson retweeted
FOCIS@FOCISimmunology22 Jan 2024
Finalize & Submit your abstract ahead of time ✔️ There's only 3 days remaining to submit your research and be a part of the FOCIS 2024 Annual Meeting! Don't wait - submit today ⏳: ow.ly/nH5T50QrTrb
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Congrats to Mianmian and Tony on this important collaborative work on thymic selection of autoreactive T cells! Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model | PNAS pnas.org/doi/10.1073/pnas.23…

Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model | PNAS

Roughly one-half of mice with partial defects in two immune tolerance pathways (AireGW/+Lyn−/− mice) spontaneously develop severe damage to their r...

pnas.org
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New in @Nature: #COVID patients with specific mutations in NFKB2 gene develop antibodies to type I interferons, which are associated with a severe disease course, often involving hospitalization and ICU care. 🧵 1/5
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Congrats to Elze and our team that have developed a new powerful tool to assess the specificity of autoimmunity in mouse models. @AtUcsf @immunox @UCSF doi.org/10.1172/jci.insight.…
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Ready for a masterpiece! Jointly led by Drs. @anne_puel, Jean-Laurent Casanova (@casanova_lab), @MAndersonUCSF, and Luigi Notarangelo, this @Nature study talks about autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency. bit.ly/474hpho
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Congrats to @Tang_Lab_UCSF Postdoc Roberto Castro Gutierrez for being named a 2024 @CIRMnews Scholar
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Excited to share new collaborative work in Nature on the genetic underpinnings of COVID susceptibility that is linked to a defect in the thymus. Great thanks to my colleagues in the Casanova, Puel, and DeRisi labs! @AtUcsf @immunox @UCSF nature.com/articles/s41586-0…

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Nature - Inborn errors of the alternative NF-κB pathway in humans impair the development of AIRE-expressing medullary thymic epithelial cells, thereby underlying the production of...

nature.com
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Congrats to the Waterfield lab on this newly identified regulator of thymic tolerance.@AtUcsf @UCSF Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance | Science Immunology science.org/doi/10.1126/scii…

Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and...

Ikaros controls medullary thymic epithelial cell development, tissue-specific antigen gene expression, and central tolerance in mice.

science.org
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