Cognitive Neuropsychopharmacologist, Assistant Professor @DellMedSchool: Drugs of (ab)use, especially psychedelics, memory, skeptical 'til proven guilty
Austin, TX
Joined January 2013
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Check out my conversation with @HamiltonMorris on psychedelics, false memories, and more now out on YouTube!
youtu.be/BuszGenKaxc?si=jDSW…
Manoj Doss not exist retweeted
Have you had a creative insight related to your work/hobby that you think was due to a psychedelic experience? Please complete this survey! Note that we don't want personal insights (e.g., "I should quit my job" or "I had a bad relationship with my boss").
tiny.cc/PsychedelicsInsights
Manoj Doss not exist retweeted
✨🧘🍄 New study 🍄🧘✨ Many people think that meditation & psychedelics might have similar effects. Our new study examines how beliefs & cognitive processes might be similar or different in consistent meditators versus psychedelic users
Share widely!
“He acknowledges that there is “ego and investment” involved in defending his ideas.” How ironic…Excellent piece, @matthabusby!
The entropic brain hypothesis has been the leading explanation for how psychedelics work in the brain, but new research suggests it's not that simple.
New for @doubleblindmag
doubleblindmag.com/the-heate…
Go check out the exhibit in Toronto before December!
How do psychedelics impact the brain?
There are a few leading theories, and Dr. @ManojDoss (Associate Professor, The University of Texas at Austin Dell Medical School) explores one of them here.
Came for @TVonTheRadio (& @BeaccchHoussse & @thestrokes), stayed for @AOC & @BernieSanders. What a family experience in NYC with my sister, brother-in-law, & my revolutionary wife @curiel_198.
Note that if I’m not mistake, AtaiBeckley CEO @SriniGRao is co-author of the linked Journal of Neuroscience paper below in which they found a potential neurocognitive enhancement from a 5-HT2A drug. We’re currently testing whether this effect generalizes to human behavior!
Interesting when 1) a 5-HT2A agonist sharpened neural tuning/precision of working memory representations (jneurosci.org/content/22/7/2…) and 2) working memory capacity (rather than precision) tends to be more readily impaired by 5-HTA psychedelics compared to NMDA dissociatives.
Interesting when 1) a 5-HT2A agonist sharpened neural tuning/precision of working memory representations (jneurosci.org/content/22/7/2…) and 2) working memory capacity (rather than precision) tends to be more readily impaired by 5-HTA psychedelics compared to NMDA dissociatives.
Ketamine Alters Tuning of Neural and Behavioral Spatial Working Memory Precision
biologicalpsychiatryjournal.…
We got a new review/model on why we think psychedelics might be particularly useful in the treatment of anxiety-related disorders.
link.springer.com/article/10…
Good work @DrHughMcGovern on carrying this through the finish line.
I was born in Texas, raised in Texas, currently live in Texas, graduated from UT (class of 2010), and now I'm faculty at UT, but I guess I'm a "problem," not a Texan (and by extension, not an American either 😔)
New paper on the phenomenology of heightened feelings of familiarity under psychedelics!
1/ Happy to share our new study, published today, looking to better understand an intriguing feature of the psychedelic experience: Why can psychedelic experiences feel profoundly familiar, even when what is being experienced is novel?
@ManojDoss
& Akira O'Connor
Wow. @jimpekar is so ahead of his time that he's publishing in the future!
I had an incredible visit to Toronto, and it was such an honor to see my work on display at @mrcolinjfleming and his colleagues' psychedelic exhibit at the @ROMtoronto. They worked so hard on this, so please check it out before December 6! #lakeontario
My chapter in the exhibit book! I should have taken more pics, but I had to capture the fact that they included @KiDCuDi among psychedelic music (something I 100% agree with!)
Lastly, it was great catching up w/@Nickkadysh & meeting my soon-to-be co-author @davidwlawrence1. Watch this space for more bizarre psychedelic effects on familiarity!
Unrelated to David’s baseball connection but maybe related to psychedelics, check out the @TheDockEllis bar!
Austin, TX & surrounding community:
We're testing the effects of psychedelics on brain function & cognition. This is not for mental health treatment, and there'll be several cognitive tasks (no lying on a couch or eyeshades), but you'll be supporting science! Please share!
Have you had a creative insight related to your work/hobby that you think was due to a psychedelic experience? Please complete this survey! Note that we don't want personal insights (e.g., "I should quit my job" or "I had a bad relationship with my boss").
tiny.cc/PsychedelicsInsights
Finally out in @JOCN_Journal. We had hoped to inhibit the amygdala using transcranial focused ultrasound (tFUS) as a proof-of-concept that the amygdala is causally involved in emotional episodic memory encoding, but this backfired…1/10
direct.mit.edu/jocn/article-…
2 decades ago, work by @The_Strange_Lab & others suggested a filtering function of the amygdala including less filtering in patients w/amygdala lesions. 9/10
pnas.org/doi/full/10.1073/pn…
doi.org/10.1523/JNEUROSCI.08…
doi.org/10.1523/JNEUROSCI.02…
doi.org/10.1017/S00332917060…
doi.org/10.1515/REVNEURO.200…
