Interested in unlocking genomics potential for increased nutrition & productivity; metagenome mining to explore novel regions of natural product chemical space
NABI Mohali
Joined November 2022
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‼️Excited to share our latest preprint‼️
Interested in natural product’s bioactivities? Check out our latest work entitled “Predicting biological activity from biosynthetic gene clusters using neural networks”.
DOI: doi.org/10.1101/2024.06.20.5…
🚀 Exciting news !!
We’re thrilled to share that our team has been awarded compute-time grants on PARAM Rudra!
This powerful HPC resource will help us scale up natural product discovery, large-scale BGCs mining, and computational exploration of nature’s chemical diversity. 🌿🔬
🎓 Master’s Dissertation Opportunities | January 2027
Mantri Lab, BRIC–NABI is inviting applications from motivated Master’s students interested in computational biology & bioinformatics.
🔬 Dissertation themes
🧬 Metagenome Mining: Discovery of novel biological patterns
🧪 Fungal Siderophore Discovery: Computational exploration and novel patterns discovery
Hands-on experience in HPC, genome/metagenome mining, BGC analysis, and natural product discovery.
📩 Share your CV/Resume at [email protected] by 30 August 2026.
📅 Dissertation starts January 2027.
Please share with interested students! 🙌
#Bioinformatics #ComputationalBiology #MastersDissertation #Metagenomics #NaturalProducts
🧵 Our preprint is now live! 🎉
Excited to share our work: “Microbial bioprospecting for benzoxazolinate-like molecules: unleashing the potential of genome mining.”
📄 Read the preprint on bioRxiv: doi.org/10.64898/2026.08.17.…
Highlights
1. Identified 277 candidate BGCs across diverse bacterial hosts.
2. Uncovered previously unexplored biosynthetic diversity across benzoxazolinate, benzobactin & ashimide-like BGCs.
3. An MLP-based bioprospecting model enables rapid detection of rare bzoz-like BGCs.
We are excited to share that our manuscript titled “BGX: A Comprehensive Pipeline for Genomic Insight into Bioactivity Prediction, Genomic Surveillance, and Novel Biosynthetic Gene Cluster Assessment” is now available on bioRxiv! 🎉
🔗: biorxiv.org/content/10.64898…
3. NPBdetect predicted 417 (ODOG) and 298 (IndeNCBI) high-confidence antibacterial BGCs.
4. Genomic surveillance enables tracking of antimicrobial resistance genes across bacterial genomes.
#bioRxiv #GenomeMining #Bioinformatics
📢Interested in microbial genome mining, natural products, or bioinformatics? We welcome collaborations on BGX, including beta testing and validation, tool development and integration, novel ideas and use case expansion, etc.
#Collaboration #ComputationalBiology #NaturalProducts
🚀 Looking for a research internship this summer?
MantriLab is offering a short-term internship opportunity for motivated students.
📌 Check out the poster for more details.
#Internship #MantriLab #ResearchOpportunity #Students
We are delighted to celebrate the successful completion of a Master's dissertation by Manvinder Jaswal from our lab. 🎓
Title: Designing an integrative framework for functional annotation and combinatorial ecological inference in microbiome and metagenome studies
Their research has contributed valuable insights. Congratulations on this achievement, and best wishes for the exciting opportunities ahead!
#ResearchLife #MastersStudent #ScientificResearch #LabLife #HigherEducation
Has anyone created a lightweight version of the JGI SMC (Secondary Metabolites Collaboratory) database for faster BGC searches and development?
#SecondaryMetabolites #antismash #NaturalProducts #bioinformatics #metagenomics #BGCs
Looking for something smaller than the full-scale SMC setup — maybe representative BGCs, clustered BGCs, antiSMASH-only outputs, or a compact indexed version for local pipelines.
Would love to know if any community project/GitHub repo exists. @kaiblin @marnixmedema @thinkgenome
Glad to have contributed to the #MIBiG 5.0 🧬Annotathon by annotating new BGCs and supporting this valuable community resource for natural products and genome mining research.
Many thanks to the organizing team for their commendable efforts and to all fellow participants for their contributions — these updates will be extremely useful for the community in the long run. Happy annotating! 🧬✨ #MIBiG #GenomeMining #NaturalProducts #BGC