Postdoc, Institute of Cancer Research | RNA modifications & AML therapeutics | Kranc Lab
London
Joined May 2019
- Tweets33
- Following272
- Followers130
- Likes181
Our latest paper on targeting TUT4/7 in acute myeloid leukaemia went live at 7PM, coinciding perfectly with the eclipse. A hike from work to watch and celebrate. More to follow tomorrow, thanks to everyone who contributed, @kamilkranc , @CarrollDonal and many, many others.
Chris Mapperley retweeted
Delighted to share our new work in @NatureCancer in collaboration with @SchofieldOxford led by @hannahjlawson & James Holt-Martyn. We found that HIF hydroxylases are potent therapeutic targets in AML. @ICR_London. nature.com/articles/s43018-0…. 1/4
Pre conference run #RNAUK2024. We're set up and looking forward to welcoming you!
Chris Mapperley retweeted
Preprint alert!
biorxiv.org/content/10.1101/…
A very enjoyable work led by @VilmaDembitz perseverance and talent but also made possible by the help provided by a wide range of excellent senior and junior collaborators. A refreshing experience for a young academic! Thread 👇 1/10
Chris Mapperley retweeted
Very happy to have taken part to the inaugural EHA research conference @EHA_Hematology! Bravo to @VilmaDembitz, @hannahjlawson, @MapperleyChris, @SyedAMian for your amazing talks 🔥
Chris Mapperley retweeted
Great to give a talk @EHA_Hematology #ehaRecon22 in Palermo! A pretty amazing place to spend a few days talking science! @QMBCI @kamilkranc
Chris Mapperley retweeted
A time and single-cell resolved model of hematopoiesis: tinyurl.com/2s3vhr8r. With @kamilkranc and @CarrollDonal groups, we have generated a new model of hematopoiesis, fit for the single cell genomics era, building on @fabian_theis group tinyurl.com/ywpxtrum. @SCICambridge
Chris Mapperley retweeted
Please direct contact me if you are interested. Funding will be available to extend position further if needed and there are lots of interesting projects in the lab and scope for more in AML and cancer metabolism
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Applications are open for a Postdoctoral Research Assistant to join Dr @PaoloGallipoli's lab at BCI @QMULBartsTheLon @QMUL to investigate the role of rewired metabolism in acute myeloid leukaemia. Find out more and apply ➡️ qmul.ac.uk/jobs/vacancies/it… Application deadline: 14 Sept
ALT Researcher's hand with blue glove, holding a tube with orange liquid on a vortex machine.
Chris Mapperley retweeted
Research technician job is available in my group at Haemato-Oncology Centre, Barts Cancer Institute. Opportunity to work in a beautiful campus in the middle of London and wonderful scientists and physicians. Promise to fulfill your desire to learn! jobs.ac.uk/job/COY889/resear…
Chris Mapperley retweeted
So pleased to see our CITED2 paper out in @stemcellreports. We found that Cited2 deletion results in HSC loss via Mcl1 & Pten downregulation. Incredibly, we reveal that unperturbed hematopoiesis can be sustained long-term while the HSC pool is depleted! doi.org/10.1016/j.stemcr.202…
Chris Mapperley retweeted
Very proud to announce our latest paper @nature showing the development and characterisation of the first-in-class catalytic inhibitor of METTL3 against AML. A superb collaboration between our lab (@TheMilnerInst, @sangerinstitute), @storm_tx and @TKLABUK
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Chris Mapperley retweeted
In a paper published today in Nature, see how exciting work at the Milner Institute, in collaboration with @storm_tx , has made a promising step towards developing a new drug for treating acute myeloid leukaemia.
bit.ly/3vk6SLB
@TKLABUK @TzelepisLab
Thanks to my examinors @RushworthLab, @GrannemanSander and supervisors @kamilkranc, @CarrollDonal aparently i'm now a Dr! Now time for a drink and to change my passport.
Congratulations to Dr @MapperleyChris for passing his PhD viva! Many thanks to Stuart @RushworthLab and @GrannemanSander for examining Chris and @CarrollDonal for great co-supervision. Good luck with your postdoc in HSC and RNA biology @QMBCI.
Chris Mapperley retweeted
Sometimes, to understand what something does you must first figure out what it doesn't do!
In the latest #preprint from our lab, we demonstrate that the peptidylarginine deiminase PADI4 is dispensible for cell-autonomous haematopoietic development
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Chris Mapperley retweeted
The O’Carroll lab is looking for talented postdoctoral research associates to join us in our quest to explore piRNA-directed DNA methylation.
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Chris Mapperley retweeted
Delighted to see our new paper in @bloodadvances. Many thanks to our collaborators and @bloodcancer_uk for funding this important research!
New research published in @BloodAdvances identifies JMJD6 as a novel metabolic regulator of blood stem cell functions. The research was a collaboration between the
@kamilkranc lab at BCI @QMULBartsTheLon, @UniofOxford @Cambridge_Uni @EdinburghUni ashpublications.org/bloodadv…
This hamper just came through the post from my PhD program @RepairPhD, @EdinUni_IRR. They put a big smile on my grumpy face. We cant have our Christmas party- but the little things matter.
