MD, PhD | PGY-1 @MGHfC Single-cell, molecular bio, neuroscience, pediatrics.
Boston, MA
Joined September 2015
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Marcus Basiri retweeted
Thrilled to see this paper out in @natBME with @SMitragotri and @Aaron_Anselmo!
In it, we describe three approaches for #drugdelivery and their history: modifying the drug, modifying the environment around the drug, and building a delivery system to bridge the two.
How has drug delivery evolved over the decades? What has changed? What has remained the same? Check out our review led by @AvaVargason with @Aaron_Anselmo in @natBME @wyssinstitute @hseas @UNCPharmacy nature.com/articles/s41551-0…
Marcus Basiri retweeted
Beautiful new preprint from @HeySunKat
Skewed X inactivation in genetically diverse mice is associated with recurrent copy number changes at the Xce locus biorxiv.org/content/10.1101/…
Marcus Basiri retweeted
Just out! Angelman syndrome has the potential to be prevented with a CRISPR/Cas9 gene therapy. Early detection, followed by early treatment will be key. Special thanks to our amazing research group and @Angelman @SFARIorg @NINDSdirector. nature.com/articles/s41586-0…
Marcus Basiri retweeted
In non-#COVID19 news, our paper describing Smart-seq3 has been published in @NatureBiotech today! nature.com/articles/s41587-0… Thanks to everyone who read the @biorxivpreprint. Do check out the final version, we have added quite a few things... ⬇️ #singlecell
Marcus Basiri retweeted
Wait, what..?!🤯 Brain control of adaptive immunity!
CRH neurons in the hypothalamic PVN & amygdala, which govern responses to fear & stress, are now shown to induce increases in plasma cell numbers & antigen-specific antibodies via splenic nerve. @nature
nature.com/articles/s41586-0…
Marcus Basiri retweeted
The gut–brain axis mediates sugar preference
nature.com/articles/s41586-0…
Marcus Basiri retweeted
The highest quality Jupyter notebook I've ever seen was just posted by... <checks notes>... ex-CEO of Instagram, Kevin Systrom?
All of us data scientists can hang our heads in shame.
h/t (@seanjtaylor )
github.com/k-sys/covid-19/bl…
Marcus Basiri retweeted
Happy to share our latest work on the multimodal transcriptional analysis on the mammalian habenula. This work was entirely led by twitter-free Yoshiko Hashikawa in the team Stuber lab @gstuber @WhoIsMarkRossi @MarcusBasiri . cell.com/neuron/fulltext/S08…
Marcus Basiri retweeted
Not the best of times for the world, but I am excited to announce that our lab website is up at namboodirilab.org. The lab will open at @UCSF on September 1, 2020. We are hiring one postdoc. If you or anyone you know is interested, please contact me by email. Please RT. 1/4
Marcus Basiri retweeted
This shows the location data of phones that were on a Florida beach during Spring Break. It then shows where those phones traveled.
First thing you should note is the importance of social distancing. The second is how much data your phone gives off.
Marcus Basiri retweeted
And then there's 3D ATAC-PALM: super-resolution imaging of the accessible genome from the Tijan and Liu labs to brighten your day. nature.com/articles/s41592-0… rdcu.be/b21uM
Marcus Basiri retweeted
KB: So today we are pleased to introduce the Chromium Single Cell ATAC + Gene Expression solution. 2 modalities in one simple workflow, both at high sensitivity. #AGBT20
Marcus Basiri retweeted
Gorin, @vallens and @lpachter extend the RNA velocity, so that when given single cell transcriptomic and proteomic data, rather than predicting what the cell will be like in the future, they infer what it was like in the past. genomebiology.biomedcentral.…
Marcus Basiri retweeted
RNA imaging and tracking in live cells using a single 57 nt aptamer fusion?!? I’ll admit I thought it would never work, but @Tewoderos14 proved me wrong. Beyond excited to share this work from @HeemstraLab and @BassellLab!
biorxiv.org/content/10.1101/…
Marcus Basiri retweeted
Check out our latest preprint on Pnoc expressing neurons in the BNST that encode and promote rapid arousal responses. biorxiv.org/content/10.1101/… Big shout out to those on twitter: @randall_ung, @MarcusBasiri, @vijay_mkn, @McHenry_Lab, @superkash, @mbruchas and @gstuber.
Marcus Basiri retweeted
I find myself having hushed conversations with MD/PhD colleagues about what happens next. My conclusion so far is that the 80/20 research/clinic split that we always talk about isn’t really available. Seems more 100% clinic, 100% research, and many leaving academia. #medtwitter
Marcus Basiri retweeted
First, scNT-seq reveals cell-type specific nascent transcription and RNA trajectories in response to brief versus sustained activation. (2/3)
Marcus Basiri retweeted
Ultra-high throughput scRNA-seq from Christoph Bock's lab! Combines combinatorial barcoding with droplet microfluidics to sequence >150,000 cells on a single @10xGenomics lane: biorxiv.org/content/10.1101/…
Marcus Basiri retweeted
I am excited to share our latest work, in which we tackle the question:
How can we predict which enhancers regulate which genes in which cell types?
nature.com/articles/s41588-0…
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