The research group account of the laboratory of Scott J. Miller at Yale University.
Joined June 2020
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Congratulations to the team for further exploring the structure of 3’-(2-Pyridyldithio)-3’-deoxyadenosine via synthetic convergence with an antibiotic, cordycepin, and MicroED. pubs.acs.org/doi/full/10.102…
Check out our latest publication highlighting our work with a common aspartic acid-based catalytic platform for the selective oxidation of varying functional groups!
pubs.acs.org/doi/full/10.102…
We are pleased to share our latest work on site- and epimer-selective hydrogenations of thiostrepton, published in @J_A_C_S! Congratulations Paul @peazy_qua_peazy for navigating catalyst control in a high-complexity molecule, unveiling some unexpected SAR. pubs.acs.org/doi/10.1021/jac…
Excited to share our latest work in JACS on asymmetric HAT catalysis, with our collaborators Knowles, Houk, and Mayer! Check out how peptide-based catalysts mediate selective radical transformations. Huge congrats to Marcus, Yiran, and the whole team: pubs.acs.org/doi/10.1021/jac…
We are pleased to share a catalytic and enantioselective approach to the synthesis of chiral 7- & 8-membered rings. Read more about Nicolò’s recent work on @JACS @ntampellini_ pubs.acs.org/doi/10.1021/jac…
Check out our latest work on catalytic atroposelective cyclocondensations, out now in @ACSCatalysis! Congratulations to Melody (@MelodyCGuo) for demonstrating how catalyst-substrate matching drives enantioselectivity in atroposelective cyclocondensations. pubs.acs.org/doi/full/10.102…
We are excited to share our latest study of asymmetric S-oxidation, out now in @JOC_OL! Congratulations Susannah, Nicolò, and Maria on their work elucidating the dual points of contact between the peptidic catalyst and functionalized thioether substrates.
pubs.acs.org/doi/10.1021/acs…
Huge congratulations to Yiran for passing her qualifying exams and becoming a PhD candidate! Your hard work and dedication have truly paid off. Here’s to the exciting journey ahead!
Miller Group retweeted
Fe/Thiol Cooperative HAT Olefin Hydrogenation: Mechanistic Insights That Inform Enantioselective Catalysis | JACS @pushingarrows @RiceUniversity @Yale @YaleChem #FeThiol #HAT #Olefin #Hydrogenation #Enantioselective #Catalysis #Cooperative #Mechansim
pubs.acs.org/doi/10.1021/jac…
Miller Group retweeted
Check out this tour de force led by @sbuzsaki @RiceChemistry and Savannah Mason @YaleChem in collaboration with @MillerGroupYale and @patholland_0! The first asymmetric radical hydrogenation with some mechanistic surprises along the way! #realtimechem
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Miller Group retweeted
Scaffold-Oriented #AsymmetricCatalysis: Conformational Modulation of Transition State Multivalency during a Catalyst-Controlled Assembly of a Pharmaceutically Relevant Atropisomer (Scott J. Miller and co-workers) onlinelibrary.wiley.com/doi/…
Congratulations to Nicolò (@ntampellini_ ) on the publication of his investigation into conformational modulation of peptidyl guanidine catalysts, now out in @ChemEurJ!
chemistry-europe.onlinelibra…
We are pleased to share our collaborative work with the Sigman, Toste, and Genentech groups on the enantioselective acylation of sulfonimidamides, now out in @J_A_C_S! Congratulations to the team, including Miller lab members Eden and Melody! @MelodyCGuo pubs.acs.org/doi/10.1021/jac…
Miller Group retweeted
Congratulations to Prof. Scott Miller on his recent appointment to Sterling Professor of Chemistry. A Sterling Professorship is considered the highest academic honor a Yale professor can receive. Learn more about his research and achievements at bit.ly/3wYmvP4.
Miller Group retweeted
Feeling like an honorary alumnus @Yale … many thanks for all the wonderful chats and great hospitality by @MillerGroupYale @ellman_lab @HerzonLab @NewhouseGroup and @GSK!
Miller Group retweeted
Thrilled to announce Prof. Scott J. Miller @MillerGroupYale as the Plenary Speaker at WIPOS 2023 (wipos.org, December 18-21, 2023) in Honolulu, HI. Register at signup.rice.edu/WIPOS2023/ to hear 42 speakers, present posters, network with organic chemists and have fun!
ALT There will be 42 speakers and also a continuous poster session associated with this symposium. One day will be dedicated to lectures from 12 young investigators (i.e. ≤10 years from starting their independent careers, including 11 pre-tenure faculty members). The remaining 3 days will feature a combined 30 speakers from both academia and industry. WIPOS 2023 will be held at the Hilton Hawaiian Village Waikiki Beach Resort in Honolulu, Hawaii. The symposium attendance will be limited to a total of 150 participants.
Our latest study of atroposelective catalysis is now out in @JOC_OL! Congratulations Susannah, Lizzy, and Simone on their work understanding the effect of functionalized substituents on internal bond rotations within pyridine N-oxides. Read at: pubs.acs.org/doi/10.1021/acs…
We are pleased to share our work in collaboration with the Anslyn Group on the determination of enantiopurity in the atroposelective synthesis of aryl triazoles. Congratulations to group members Melody and Sooyun!
pubs.rsc.org/en/content/arti…