@MincLaura

Post Doctoral Fellow at Wellcome Sanger Institute

 Cambridge, England
Joined February 2018
  • Tweets1.7K
  • Following1.4K
  • Followers334
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Our story is out! Using sc long read RNA-seq we showed that #HSPC co-express different #isoforms in key regulators of hematopoesis and we defined novel signature of #ageing. @CommsBio Plus, new job at Wellcome Sanger Institute for more exciting science! nature.com/articles/s42003-0…

Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic...

Communications Biology - Single-cell transcriptomics using long-read sequencing achieves both gene and isoform expression in haematopoietic stem and progenitor cells, providing novel insights into...

nature.com
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LauraMinc retweeted
ISEH@ISEHSociety9 Jan 2025
The first Preprint Watch for 2025 is plentiful: 9 preprints focusing on Acute Myeloid Leukemia, but also spatial fate mapping meets barcoding, how cell fate decisions occur in hematopoietic progenitors, and more! Read now➡️ simplyblood.org/
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Excited to share our new preprint in which we address: (1) Accurate sequencing of sperm at scale (2) Positive selection of spermatogenesis driver mutations across the exome (3) Offspring disease risks from male reproductive aging [1/15] medrxiv.org/content/10.1101/…

Sperm sequencing reveals extensive positive selection in the male germline

Mutations that occur in the cell lineages of sperm or eggs can be transmitted to offspring. In humans, positive selection of driver mutations during spermatogenesis is known to increase the birth...

medrxiv.org
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🚨New analysis from @royalsociety UK visa costs for researchers: 🫣 21x higher than France (Talent passport for researchers) 😱34x higher than Germany (Scientific visa) 😬Have increased by 126% since 2019 while other countries have made theirs cheaper royalsociety.org/news-resour…
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LauraMinc retweeted
ISEH@ISEHSociety11 Mar 2024
The ISEH community deeply mourns the loss of Connie Eaves; a revered society member, Past President, former ExpHem journal editor, and incredible scientist. Connie will be remembered not only for her seminal works, but for her generous mentorship of generations of scientists.
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I had the honour and the fortune of meeting and interviewing Dr Eaves while serving on a committee. A kind, passionate and ispiring scientist. I will surely treasure what I learned during our meeting. Very saddened to hear about her passing. med.ubc.ca/news/remembering-…
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We have an exciting opportunity for an Advanced Research Assistant to join the Flow Cytometry team here at the Wellcome Sanger Institute. Interested? Please visit this link for more details sanger.wd3.myworkdayjobs.com…
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LauraMinc retweeted
ISEH@ISEHSociety12 Feb 2024
Join the Junior Faculty Committee as they host the first online Mini Symposium on 27 March! The event will include keynote presentations and short talks selected from a call for abstracts. Submit an abstract by 1 March and register today❗ Learn more: iseh.org/2024MiniSymposium
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Another fantastic @ISEHSociety initiative and platform for #juniorfaculty #NewPI #postdoc to present their research alongside invited talks by @awilkinsongroup @scienceadvocacy @theclotthickens @stephxie Register and submit abstracts: iseh.org/2024MiniSymposium
ISEH@ISEHSociety12 Feb 2024
Join the Junior Faculty Committee as they host the first online Mini Symposium on 27 March! The event will include keynote presentations and short talks selected from a call for abstracts. Submit an abstract by 1 March and register today❗ Learn more: iseh.org/2024MiniSymposium
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Sunday 11 February is #InternationalDayofWomenandGirlsinScience, celebrating the critical role women and girls play in STEM. We have some incredible #WellcomeGenomeWomen helping us deliver life-changing research. We’ve highlighted a few below, or head over to the blog for more ⤵️
Zoom background with the text: #WellcomeGenomeWomen International Day of Women and Girls in Science 11 February 2024. In the bottom left hand corner 'Wellcome Genome Women' in a pink circle with a yellow triangle and a smaller purple circle. On the right hand corner, a silhouette of a womans profile and the Wellcome Genome Campus branding and social media handles.

ALT Zoom background with the text: #WellcomeGenomeWomen International Day of Women and Girls in Science 11 February 2024. In the bottom left hand corner 'Wellcome Genome Women' in a pink circle with a yellow triangle and a smaller purple circle. On the right hand corner, a silhouette of a womans profile and the Wellcome Genome Campus branding and social media handles.

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The @genomeresearch editors are at #AGBT24! Come chat with us! 🧬
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Cancer doesn’t recognise borders and no one country can beat it alone. The UK has some of the brightest and best scientists, but also one of the most expensive visa systems in the world. That is putting off top talent from coming here and puts scientific progress at risk. Our new policy paper sets out the steps the UK Government should take to attract more brilliant scientists to come and work here #CancerManifesto news.cancerresearchuk.org/20…
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Excited to be involved in teaching this new course on Wellcome Genome Campus: 'Designing Laboratory-Based Training: A Workshop for Building Capacity in Genomics Technologies’. Please RT! :) coursesandconferences.wellco…
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Come and be one of our amazing speakers at the Mutations in Time and Space conference! Abstract submission for platform presentations closes next week. 23-25 April 2024 in beautiful Edinburgh - register at mutationmeeting.com
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Large-scale analysis has uncovered the interplay between cancer-driving mutations and inherited genetic variants in a rare type of #bloodcancer 🩸 Find out more here 👇🏻 sanger.ac.uk/news_item/role-… @jyoti_nangalia @nicolesoranzo

Role of inherited genetic variants in rare blood cancer uncovered

Combining three different sources of genetic information has allowed researchers to further understand why only some people with a common mutation go on to develop rare blood cancer

sanger.ac.uk
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LauraMinc retweeted
ISEH@ISEHSociety9 Jan 2024
Join the ISEH Junior Faculty Committee for their February webinar! This live webinar on 6 February will feature talks from Profs. Peggy Goodell and Ricky Johnstone as they discuss key leadership skills for your academic career. Register for free today! iseh.org/ISEHWebinars
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💫ONLINE NOW @NatureCancer – the #2023Generation – 12 group leaders share their journey to becoming an independent PI. Very inspiring stories, please do not miss them! nature.com/articles/s43018-0…
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Retaining postdocs by recognizing their worth go.nature.com/3YYLniy
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Is #cancer drug resistance heritable or plastic? Genetic or non-genetic? How do we tell those apart? We just begun measuring the temporal dynamics of evolving cancers using controllable patient-derived #organoids. We need more experiments+theory! biorxiv.org/content/10.1101/…
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❄️ 2 million households have turned off their fridge or freezer to save money 🗓️ Nearly half of these households did this for the first time in the last six months 🍲 2.8 million households hold debt that they had taken out to help pay for food 🧵(1/3) theguardian.com/business/202…

Millions of UK households forced to unplug fridge or freezer amid rising bills

Families resorting to ‘desperate measures’ and struggling with ‘frightening’ level of hardship amid cost of living crisis

theguardian.com
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