PhD student from @LMU_Muenchen and @UniBonn. Studying structure and evolution of enhancers in fruit flies
Joined January 2016
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Mariam Museridze retweeted
So it’s going to spend 3 years crippled by insecurity, messing up everything it tries, contemplate quitting as it’s friends get rich and start families, before finally pulling it all together in a manic amphetamine fueled two month stretch and making an amazing discovery nobody reads because it’s paywalled?
Very excited to finally share our latest paper! 🧬🪰
science.org/doi/10.1126/scia…
Mariam Museridze retweeted
An AI model generates thousands of synthetic CREs with programmed functionality. The CREs drive cell-type-specific expression in cell lines and show specificity in vivo. nature.com/articles/s41586-0… #NBThighlight
Mariam Museridze retweeted
Academia is held together by caffeine, free labour, and the two people who nod encouragingly during presentations
I’ll be presenting this project as a poster at the upcoming #EMBL #Transcription and #Chromatin conference. Come check it out!
So excited to share our new preprint! 🎉
In this project, we're revisiting enhancer modularity with quantitative approaches in Drosophila 🪰🧬
Summary in the thread below. ⬇️
biorxiv.org/content/10.1101/…
So excited to share our new preprint! 🎉
In this project, we're revisiting enhancer modularity with quantitative approaches in Drosophila 🪰🧬
Summary in the thread below. ⬇️
biorxiv.org/content/10.1101/…
Our main conclusions are:
• Enhancers are much bigger than previously thought and extensively overlap.
• The body enhancer comprises at least 3 activities.
• Distribution of regulatory information is not even.
• Enhancers show different levels of functional modularity.