Mo Neuro222 retweeted
🧵 IgG4-related disease: New treatment guidelines for 2026
The IgG4ward! Foundation guidelines, published in The Lancet Rheumatology (November 9, 2026), provide a major update to the 2015 treatment framework.
Here are 10 key updates for clinicians.
#RheumattDoc #MedTwitter #RheumTwitter #rheumatology #igg4relateddisease @docakx @IhabFathiSulima @CelestinoGutirr @DurgaPrasannaM1
Mo Neuro222 retweeted
The new term that replaces mycotic aneurysms: Infective native aortic aneurysms (INAA)! Features and diagnostics keystones! Bovine pericardium stapler homemade aortic graft! @SWexner @pferrada1 @BJSAcademy @CiruAndes2
Mo Neuro222 retweeted
2026 ACR/SAA/SPARTAN Guidelines for the Treatment of Axial Spondyloarthritis, Liron Caplan. #ACR26
Against treat-to-target strategy!
Mo Neuro222 retweeted
Mastering thalamic vascular variants is crucial in stroke imaging! 🧠 Let's review the 4 patterns of paramedian thalamic supply:
🔹 Type I: Symmetrical independent arteries (most common normal anatomy)
🔹 Type IIa: Asymmetrical origin from a single PCA
🔹 Type IIb: Artery of Percheron (A single common trunk bifurcating to supply bilateral thalami) ⚠️
🔹 Type III: An arterial arcade pattern connecting the PCAs
Recognizing the AOP (Type IIb) is critical in the reading room—occlusion means bilateral thalamic infarcts from a single vessel!
#Neuroradiology #NeuroTwitter #Stroke #Neuroanatomy #MedEd #FOAMrad
Mo Neuro222 retweeted
We have just updated our stroke differential diagnosis checklist with this paper neurochecklists.com/explore/…
Mo Neuro222 retweeted
To be a philosopher is to be constantly in awe at things that everyone else takes for granted.
Mo Neuro222 retweeted
Secondary brain injury in spontaneous intracerebral hemorrhage: A narrative review of pathophysiological mechanisms, translational therapies, and future directions
ovid.com/10.4103/bc.bc_81_26
Mo Neuro222 retweeted
Emerging therapies expected to make a difference in Parkinson's disease management
#PD #Parkinson #therapies #emerging #stemcell #levodopainfusion #genetherapy
@PRDAssociation
Log in :
prd-journal.com/article/S135…
Mo Neuro222 retweeted
Emphysematous cholecystitis with pneumobilia.
50-year-old diabetic male with poor glycemic control.
Mo Neuro222 retweeted
Rapid sequence induction
There is insufficient evidence for many of the elements of RSI to determine whether they reduce patient harm or to state confidently that they do not.
@doctimcook @altgm
#AnSky #MedX #MedTwitter
doi.org/10.1111/anae.70449
Mo Neuro222 retweeted
Tu cerebro puede modificar la forma en que late tu corazón. Aquí te explico la neurociencia detrás de esto. Una fascinante revisión científica de 2026 explora cómo el cerebro influye directamente en la función cardíaca y por qué esta conexión es relevante para la salud 👇
Mo Neuro222 retweeted
🫁🚑 Manejo del SDRA en el Paciente con Trauma
💥Lesión "Multi-Hit"
🩻Imagen Multimodal
🌬️Soporte Respiratorio
💧Manejo de Fluidos
💉Analgesia y Control del Dolor
🔰📚Intensive Care Medicine 2026
Artículo Completo👇🏻✅🆓
t.me/DeCaUMX
Mo Neuro222 retweeted
輸液忍容性(fluid intolerance)とは、狭義ではこの研究にあるような「臨床的うっ血や充満圧上昇のシグナル」というのが一般的でしょうか。
一方でシグナルが出ていなくても、心不全やCKD、先行する重症疾患により既に体液過剰がある場合など、広義の輸液忍容性の低下とすることもあります。
予防的な解釈をしたり、目の前のうっ血だけではなく少し先の体液過剰を見据えた判断基準にしたり、ここらへんで用語の混乱を招いている気がします。
ちなみにこのRCTは症例が登録されなくなり、管理上の理由から早期中止されています。
適格基準がやや厳しく介入プロトコルが複雑なので、Feasibilityの問題かもしれません。
link.springer.com/article/10…
Mo Neuro222 retweeted
Basic physiology of Fluid responsiveness in ICU
An detailed article for those interested in hemodynamics , fluid physiology with clinical implications
link.springer.com/article/10…
#Hemodynamics #Criticalcare #FluidTherapy #NephTwitter
Mo Neuro222 retweeted
Trombólisis en el Ictus Isquémico Agudo. 🧠💥💉
✨️ Review2026 @NEJM 💯
✅️ Tenecteplasa > Alteplasa.
▪️La tenecteplasa presenta mayor especificidad por fibrina y vida media más prolongada, permitiendo su administración en bolo único. En 2025, la FDA aprobó tenecteplasa para el ictus isquémico agudo.
▪️Los ensayos clínicos han demostrado no inferioridad frente a alteplasa en eficacia clínica y seguridad, con posible mayor recanalización arterial.
💉 Dosis: 0.25 mg/kg IV (máximo 25 mg), frente a alteplasa 0.9 mg/kg IV (máximo 90 mg).
✅️ Ventana terapéutica.
▪️La ventana convencional de 4.5 horas puede extenderse hasta 24 hrs en pacientes seleccionados mediante neuroimagen avanzada, cuando existe tejido cerebral potencialmente recuperable (mismatch núcleo–penumbra).
🧐🔎 El paradigma evoluciona del tiempo transcurrido hacia la viabilidad tisular.
▪️En pacientes con ictus leve no discapacitante, los ensayos recientes no demostraron beneficio de trombólisis frente a doble antiagregación. Sin embargo, un NIHSS ≤4 puede subestimar déficits clínicamente relevantes, como debilidad incapacitante de la mano o alteraciones de la marcha.
✅️ Trombólisis + Trombectomía es mejor.
▪️La trombólisis aislada consigue recanalizar aproximadamente 10–30% de las oclusiones de grandes vasos, frente a tasas de hasta 90% mediante trombectomía mecánica.
📝🆓️⤵️
doi:10.1056/NEJMra2519017.
t.me/medicinainternaconsoque…
Mo Neuro222 retweeted
Hallmarks of colorectal cancer subtypes👇
nature.com/articles/s41568-0…
(Origins and heterogeneity of colorectal cancer)
Mo Neuro222 retweeted
My new book is out- Lupus: The Essential Guide
It is 100% for patients. Pure practical advice for everything lupus. Unlike my Lupus Encyclopedia, I removed all the scientific, medical background so that readers can immediately read and know what is most important. Thorough index…. Look up any lupus drug or lab and get practical information instead of a long list of potential side effects that may very rare. It is also cheaper and more affordable at your favorite online bookstore
Mo Neuro222 retweeted
New in Cephalalgia Reports!
This paper compared the ICHD-3 and DC/TMD diagnostic systems for headache attributed to temporomandibular disorder in the OPPERA-II cohort and found that the two approaches identify overlapping but clinically distinct headache presentations.
journals.sagepub.com/doi/10.…
#migraine #headache #brain #pain #neurology #neuroscience





































