MSCA Posdoctoral fellow at @UCC @Pharmabiotic 🇮🇪Working on the Enteric Nervous System and gut microbiota in autism. Former PhD at @TENS_lab (🇫🇷🇨🇦)
Cork, Ireland
Joined September 2021
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Morgane E. Le Dréan retweeted
C. symbiosum promotes enteric neuron loss in IBD
C. symbiosum-derived succinate rewires macrophages to sustain IL-1β, thereby activating neuronal NLRP3 & driving neuron loss. Targeting C. symbiosum w/phage endolysin preserves neurons &dampens inflammation
cell.com/cell-host-microbe/a…
My 2nd PhD paper with @TENS_lab is out !
We show that secondary bile acid; deoxycholic acid, increases synaptic density and regulates enteric neurons activity in vitro, highlighting the relevance of secondary bile acids in the microbiome-ENS axis and gut physiology 🦠⚙️👁️👁️
The Microbiota-Derived Metabolite Deoxycholic Acid Regulates Enteric Neuron Activity and Connectivity
onlinelibrary.wiley.com/doi/…
Morgane E. Le Dréan retweeted
Throwback Thursday: The 5th #nEUROgastro TANDEM meeting, held just prior to #NeuroGASTRO2025, continues the successful mission of empowering the next generation of experts in #Neurogastroenterology by building a strong network of young investigators.
🔗 bit.ly/4nLafWV
Thank you so much for this opportunity !
I had the most amazing time at Neuroscience Ireland 2025 in beautiful Belfast ! 🇮🇪🧠@NeuroscienceIRL
#NSI2025 #travelbursary #entericnervoussystem #belfast
🌟 NSI Travel Grant in Action! Grateful to Morgane E. Le Dréan, for sharing her work at #NSI2025: on how secondary bile acids affect enteric neurons — and for representing the gut–brain connection so brilliantly! 🧠
@Pharmabiotic @MorganeELD
Exhibit 2 😂🫶🏻🥑🏃🏻♀️(we had way too much fun doing it)
Are you interested in how exercise may affect symptoms of depression and mood? Researchers at APC Microbiome Ireland @ucc are now recruiting participants!
If interested email [email protected] or click here tinyurl.com/Move4Mood
Secret passion of mine: modelling for gut microbiome research 😂🫶🏻 🥑🏃🏻♀️
Help us investigate how the food we eat influences the composition of the gut microbiota and how these microbes communicate with the brain.
•‘Check your eligibility here: forms.office.com/r/BD70RMuuH…
Thank you again for this amazing opportunity #Neurotandem2025. @LauraDzMa 🫶🏻👩🏻🔬👩🏻🔬🇮🇪&🇩🇪
Congratulations to APC's @MorganeELD - @UCC
& @INSPIREMSCA who won the EU translational TANDEM competition at @esnm_eu
TAMDEM is an initiative supported by the ESNM pairing scientists & clinicians to develop collaborations
@InsermGrdOuest @NantesUniv
#neurogastro2025
Morgane E. Le Dréan retweeted
Last week's #NeuroGASTRO2025 was a meeting of firsts.
✔️ as a speaker in the future of Neurogastroenterology session @esnm_eu #yESNM #Neurotandem2025 @LBBB_meeting
✔️ with 🌟 PhD student Carla presenting her work from @UCC @Pharmabiotic
I also had the pleasure of presenting my second PhD paper from @TENS_lab on secondary bile acids and enteric neuronal connectivity and listen to Michel Neunlist (@TENS_lab) talk’s on the ENS and neurodegenerative disorders @esnm_eu @InsermGrdOuest @NantesUniv #neurogastro2025
Tandem 2025 for early career researchers in Neurogastro was an amazing experience ! I am absolutely thrilled to announce that our project with Dr. Laura Díaz (@LauraDzMa) on IBS and menstrual pain won the Tandem Funding ! #NGM2025 @Pharmabiotic #NeuroGASTRO2025 #ESNM2025
Morgane E. Le Dréan retweeted
🎉 The #NeuroGASTRO2025 Tandem Meeting kicked off yesterday with an amazing team of young researchers! 🙌 Inspiring welcome words by Qasim Aziz, host of this year’s #NeuroGASTRO meeting in #London, set the stage for exciting days ahead. 💚
Morgane E. Le Dréan retweeted
🆕🔥Phosphorylated pyruvate dehydrogenase serves as a #novel histological marker of neuronal inactivation in #ENS‼️
✅Neuronal activity using #TTX & #Veratridine revealed⏩pPDH levels are inversely correlated with neuronal firing👏
👉onlinelibrary.wiley.com/doi/…
@ANMSociety @esnm_eu
Morgane E. Le Dréan retweeted
🚀 #Pint25 in #Cork
🍄🦀🧬 Small Cells, Big Discoveries: Uncovering the Power of Proteins and Metals
📅May 21st📍Old Oak
Interested in your antifungal drugs, cancer cells and protein synthesis? Get your FREE ticket here: pintofscience.ie/event/atoms…
Morgane E. Le Dréan retweeted
🚀#Pint25 in #Cork
🧠 🚺 🦠 The Gut-Brain Axis: How Your Microbes Talk to Your Mind
📅May 19th 📍The Roundy
Interested in microbiome, women's health, lifestyle changes and Alzheimer's? FREE ticket here: pintofscience.ie/event/beaut…
@pintofscienceIE @Eoflat
Morgane E. Le Dréan retweeted
🚀#Pint25 Cork: 9 Incredible Topics, 5 Fantastic Venues! 🌟
Join us 19-21 May for Pint of Science Cork! Experience fascinating talks on topics like microbes, baby brain development, & sustainable futures from 19:00 to 21:00 each evening!
Don't miss out! 🧪🍻#PintofScience
Morgane E. Le Dréan retweeted
🎉Introducing #Pint25 Cork Volunteers! 🎉
Meet the dedicated team bringing Pint of Science Ireland to Cork, 19-21 May!
Thanks to their hard work, the festival will be a memorable celebration of science, innovation, and community.
Stay tuned for event details and ticket sales!
Morgane E. Le Dréan retweeted
APCs Microbiome-Gut-Brain Axis Research Group @UCC step forward in Solidarity with all women for #InternationalWomensDay
#AccelerateAction #IWD2025
@Researchirel
@jfcryan @UCCpsychiatry @UCCResearch
Wonderful #InternationalWomensDay even at @UCC @Pharmabiotic celebrating research on women’s health. Here is Dr. Siobhain O'Mahony @somahony1 from @Pharmabiotic talking about guy microbiome and menopause ! 👏🏻 #femmebiome #WomensDay2025 @uccinnovation #microbiome #womenshealth
Morgane E. Le Dréan retweeted
Examining microbiota's role in digestive disorders at #FNM2024! Michel Neunlist presents on Nov 8 "Defects in the Crosstalk Between #Microbiota and the Intestinal Epithelial Barrier", focusing on digestive disorders in women with chronic pelvic pain. #DigestiveHealth #neurogastro
Morgane E. Le Dréan retweeted
With a novel colonic luminal sampling method we showed that faecal samples 💩 are indeed a useful proxy for large intestinal #gutmicrobiota 🦠 & inter>intraindividual differences - something we so far only took for granted.
📖 newly out in Gut Microbes👇🏼
tandfonline.com/doi/epdf/10.…
