@NeuertL

PI at @VanderbiltU @VUBasicSciences @VanderbiltMPB focusing on Quantitative Systems Biology of Dynamic Signal Transduction and @GeneRegulation in Single Cells.

 Vanderbilt University
lab.vanderbilt.edu/neuert-lab/
Joined December 2016
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📣 Featured in Nature Communications: Vanderbilt professor Dr. Gregor Neuert is uncovering the complexity of long noncoding RNAs with advanced single-cell technologies. 📖 Read the article by the Vanderbilt School of Medicine Basic Sciences: 🔗 hubs.la/Q03mxM6y0 @vubasicsciences #BiomedicalEngineering #BMESCommunity

Cracking the code: How studying single cells reveals the secrets of noncoding genes

In a recent study, Vanderbilt researchers address a significant gap in our understanding of how noncoding regions of the genome regulate important biological processes, such as X-chromosome inactiv...

medschool.vanderbilt.edu
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Cracking the code: How studying single cells reveals the secrets of noncoding genes medschool.vanderbilt.edu/bas…

Cracking the code: How studying single cells reveals the secrets of noncoding genes

In a recent study, Vanderbilt researchers address a significant gap in our understanding of how noncoding regions of the genome regulate important biological processes, such as X-chromosome inactiv...

medschool.vanderbilt.edu
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Transcriptional stochasticity enables the Xist–Tsix locus to switch between lncRNA control modes. Medium transcription lays H3K36me3 to curb Xist; high transcription triggers polymerase interference. Variability isn't noise—it’s regulation! #lncRNA #XCI nature.com/articles/s41467-0…

Transcriptional stochasticity reveals multiple mechanisms of long non-coding RNA regulation at the...

Nature Communications - This study reveals how stochastic transcription regulates Xist and Tsix through multiple mechanisms. Using single-cell imaging, the authors demonstrate that transcriptional...

nature.com
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Our latest study reveals that gradual stress enhances cell growth and minimizes volume reduction, linked to a logarithmic signaling mechanism in the yeast MAPK #Signaling #QuantitativeBiology sciencedirect.com/science/ar…
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The drug development pipeline is costly and inefficient. In their new Comment, C. Leasure & G. Neuert argue that the effects of pharmacokinetic drug profiles on cellular behaviour should be tested in vitro earlier in drug development! @NeuertL @VanderbiltU go.nature.com/4bv2lvW
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@YaaKumah stays with us for our first panel session. She is joined by @neurdylab’s Roza Bayrak (@redgreenblues) and @NeuertL’s Dr. Gregor Neuert for a discussion on AI’s Impact on Research.
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Just because the concentration of stimuli changes doesn't mean cells respond in the same way. @AlexThiemicke & @NeuertL review on cell sensitivity to environmental rate changes reveals a widespread and underappreciated fundamental property of cell signaling - rate thresholds.
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Rate thresholds in cell signaling have functional and phenotypic consequences in non-linear time-dependent environments frontiersin.org/articles/10.…
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@VU_QSBC @BiomedVandy @scell_papers @NeuertL @BioPapers #signaltransduction #systemsbiology #ratethreshold
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Join us TOMORROW as we host Dr. Zachary Fox @zachrfox speaking on "Applications of Quantitative Systems Biology and Machine Learning." March 15th at 12PM RRB 436 & Zoom Zoom Registration Link: us02web.zoom.us/meeting/regi…
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This spring: Vanderbilt Data Science Institute hosting AI Revolutions Symposium March 27/28 vanderbilt.edu/datascience/2…

Vanderbilt Data Science Institute hosting AI Revolutions Symposium March 27/28

The possibilities of Artificial Intelligence have advanced at an exponential rate in recent years. Extraordinary models like ChatGPT allow you to generate a research paper in seconds or have a...

vanderbilt.edu
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Our latest preprint constructs phylogeographic maps of tumor evolution, tracking clonal and microenv changes along progression pseudotime. Excited to share this atlas as a rich resource for spatial analysis of human CRC! Grad Student- @cody_heiser doi.org/10.1101/2023.03.09.5…
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We are thrilled to host the 14th annual International Conference on Systems Biology of Human Disease! June 19th - 22nd. Checkout sbhdnashville.org for program details and more information on how to register!
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How are the research projects from @Hodges_Lab, @ceelox4, @scbiolab, @quarantalab, @KenLauLab, and @NeuertL similar to one another? They all use #SystemsBiology and #BigData approaches. It's complicated—but this explanation of their work isn't. medschool.vanderbilt.edu/bas…
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#UQBIO22 welcome video featuring @BMunsky and microscopy videos from frequent lecturers @NeuertL, @BioKenLyon & @tim_stasevich. Learn to measure, analyze, model & predict single-cell and single-molecule gene regulation at this year's summer school (q-bio.org).
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We have an opening for a research assistant ecsr.fa.us2.oraclecloud.com/…
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Cells respond differently to gradual vs. abrupt changes in their environments. Check out this new protocol by @hjashnsaz & @neuertL combining experimental and computational methods to create better models of how cells respond to gradual stimuli. @VU_QSBC doi.org/10.1016/j.xpro.2021.…
Graphical abstract from the paper describing the new method in a simple 5-part flow chart. The first step is experimental (working with cells), while later steps depict how a mathematical/computational model can be generated, optimized, and tested based on that data.

ALT Graphical abstract from the paper describing the new method in a simple 5-part flow chart. The first step is experimental (working with cells), while later steps depict how a mathematical/computational model can be generated, optimized, and tested based on that data.

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Hands on description by @hjashnsaz in collaboration with @zachrfox & @BMunsky on how to infer #predictivemodels from #signaling #data in #timevarying environments in @STARProtocols @VanderbiltU #computationalbiology star-protocols.cell.com/prot…
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#ImmigrantHeritageMonth is coming to a close, but we wanted to keep celebrating the contributions of immigrants to the science we do in Basic Sciences. So - we are launching a new video series to #CelebrateImmigrants. Each month we'll be highlighting a different scientist! 🌍
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