Key Paediatric Intensive Care articles all-in-one-place @Dr_Hari_Krishna @OsamaHosheh @DrToyinOcholi https://xitter.cf/t.co/gG8NVgdUTc #PedsICU **PICCHub app**

Joined June 2015
#PedsICU #Bestof2024 collection has just been published. Put together by @OsamaHosheh @DrToyinOcholi @Dr_Hari_Krishna with inputs and spanish translation from @sgdambrauskas. The collection includes 33 articles. Pubmed collection [bit.ly/PedsICU_Bestof2024] has 32 articles
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🌡️ New research has developed and validated temperature trajectory-based phenotypes of pediatric sepsis. The “hypothermic” trajectory-based phenotype was independently associated with worse clinical outcomes. 📖 Read more in PCCM: ow.ly/5WGY51009MJ #PedsICU #SCCM @SCCM
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Useful synthesis. In the Atlanta cohort (Pediatr Transplant 2024), kids extubated in the OR were older, with lower PELD and less transfusion. Did the 12 studies adjust for severity, or is lower mortality partly telling us who was well enough to extubate early?
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Ethical Challenges of Extracorporeal Membrane Oxygenation: Enhanced Recovery After Surgery Cardiac Society Consensus on Key Issues and Practical Recommendations ASAIO Journal 72(7):p 544-552, July 2026. | DOI: 10.1097/MAT.0000000000002707 ow.ly/5MMM51005YV #ASAIOJ #ECMO
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For learners navigating this range of topics, I’d make a “question-to-paper” map: choose one clinical uncertainty, then explain which study design could answer it before selecting a paper. A one-line clinical question beside each collection entry would be a useful teaching aid.
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⁉️When to extubate after a child receives a liver transplantation? ⚡️Our meta-analysis of 12 studies found immediate extubation associated with lower reintubation, mortality, and shorter length of stay. @PALISInet Liver Failure Special Interest Group #PALF @PICJournalWatch @aakashdeeparora @MarcoDaverioMD @MattGoldPedsCCM Giacomo Berti, Goda Laucaityte, @emmaaaaa8 #pediatrics #childhealth #livertranslantation #PedsICU @pccm_doc @DfarmerDouglas @VSLanziotti #pediatricacuteliverfailure Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis | European Journal of Pediatrics | Springer Nature Link
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Children with sepsis: guidelines say to consider hydrocortisone only for refractory shock. Following up on 5119 children from the SENTINEL study across EDs in Australia/NZ, Long et al. (PREDICT network) report on what's happening in real-life practice. bit.ly/4AFB2eJ
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Ireland began offering nirsevimab, a monoclonal antibody against RSV, in September 2024. What did this mean for critical care transfers of babies with bronchiolitis to intensive care units? Moore and colleagues compare the winter before and after: bit.ly/4tYALjO
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I built an interactive echocardiography tutorial with Claude Code. Chapter 07: a 3D heart, the standard imaging views, the probe position, and simulated ultrasound video.
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A point-of-care fingerprick test could spare feverish babies unnecessary antibiotics AND invasive procedures. This 25-centre European trial cut antibiotic use from 38% to 26% and lumbar punctures by 57% — with no drop in safety. Read more: adc.bmj.com/content/111/10/8…
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😝 We know adherence to LTVV in #ARDS isn’t perfect 🎯… But is non-adherence universal? Just out in #journal_CHESTCritCare, Ingraham et al look at provider-level variability 👨‍⚕️👩‍⚕️: chestcc.org/article/S2949-78…
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🚨 WORKSHOP SPOTLIGHT Extra corporeal therapies: CRRT → plasma & red cell exchange 📍 St Mary’s Hospital 📅 4 Nov 2026 | ⏰ 10:00–16:30 🔗 Spaces limited: pccslondon2026.co.uk
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📊 Research Summary: A permissive #BloodPressure target in pediatric critical care was associated with lower vasoactive drug exposure without increased adverse events or kidney replacement therapy vs usual care. ja.ma/4ACNiwJ #WFPICCS26 @WFPICCS
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Among patients with acute ischemic #Stroke who underwent successful #EndovascularTherapy for anterior circulation large vessel occlusion, adjunctive intra-arterial tenecteplase was associated with a higher rate of excellent functional outcome at 1 year vs standard medical treatment. Mortality at 1 year was similar between groups. ja.ma/4jsyxX5
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In #PedsICU research, the future is now! PICU-CONNECT (The PICU Network of research networks) is here to stay Check our webpage! picuconnect.org/
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