Almost a year later and these charts still have me squinting! Quite the adventure, fueled by an amazing amount of energy and talent from our team alongside collaborators. @UCSF @GladstoneInst
Replying to @j_eyquem
We have been asked many times: could in vivo generated CAR T cells work in solid tumors? @PL_Bernard tested it and
YES!
In a uterine Sarcoma model, we show that a single injection of vectors delivering a TRAC-B7H3-CAR can achieve complete responses in our humanized mouse model
After 4 years of thesis work at @crcm_marseille, I'm now a doctor !
A huge thank you to @GeoffGuittard and @NUNESJacques1 for trusting me and teaching me so much.
Thanks to @laliguecancer for the support.
Time to leave the nest now, and what a nest it was!
@TumImmuno_CRCM
Twice in a row.
I’ll probably never get an #ERC grant, but last night, thanks to a fantastic team, I did win something BIG: the legendary blindtest of @crcm_marseille.
Apologies to @TumImmuno_CRCM and @ChrisGinestier. You guys will do better next time 🤪
PL Bernard retweeted
From the September 15 issue—
CD25high Effector Regulatory #TCells Hamper Responses to PD-1 Blockade in Triple-Negative #BreastCancer, by Fattori et al.
bit.ly/454sOvG
@anne_chretien @TumImmuno_CRCM
PL Bernard retweeted
Hello everyone,
We are recruiting a 3-yearpost-doc in immunity and Cancer team in Marseille (France) to work on cell therapy in immuno-oncology. Please contact me if you are interested [email protected] or transfer this offer to find the ideal candidate.
Thanks !
PL Bernard retweeted
Such a plesure to close this tremendous scientific meeting thank you again to the canceropole for this great opportunity.
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PL Bernard retweeted
New #JITC article: Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors bit.ly/3BWu5sE @MyeLau_Gorvel @NUNESJacques1 @GeoffGuittard
PL Bernard retweeted
New #JITC review: Negative intracellular regulators of T-cell receptor (TCR) signaling as potential antitumor immunotherapy targets bit.ly/3Wsr3WC @lavolodon @PL_Bernard @GeoffGuittard @NUNESJacques1
PL Bernard retweeted
Brand new published protocol from @TumImmuno_CRCM !
You'll discover here some secrets of the platform, on how we can generate high dimension data and explore the immune system of cancer patients.
sciencedirect.com/science/ar…
PL Bernard retweeted
Here it is !!!
The very first paper of the #REMAP4Kids team was published today in @eBioMedicine (although we won’t be officially created before Jan 2024).
authors.elsevier.com/sd/arti…
A quick thread to explain what we found.
1/n – at Lyon, France
PL Bernard retweeted
Une étude parue dans la revue "Cell" décrit l’identification d’un mécanisme épigénétique propre aux femmes, qui est impliqué dans le développement de tumeurs agressives.
l.franceculture.fr/fsQ
Thrilled to share my first research paper out in @jitcancer ! Huge thanks to every person involved @EricVivier1 @Dr_Nick_Bikes, and especially to @NUNESJacques1 & @GeoffGuittard
Stay tuned for more exciting data from @TumImmuno_CRCM !
New #JITC article: Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity bit.ly/38C1u0N @PL_Bernard @NUNESJacques1 @GeoffGuittard
And of course, warm thanks to @laliguecancer for supporting my PhD project since 2019.
PL Bernard retweeted
Full amphi for the 3rd annual ICI conference ✌️✌️✌️. @CIML_Immunology @univamu























