Cambridge, England
Joined October 2011
- Tweets2.8K
- Following1.1K
- Followers1K
- Likes11K
Pablo Rodríguez Mier retweeted
There are three elements here: (1) being clueless about Chinese performance in engineering and research in general (2) being clueless about the situation in AI in particular (3) having some racist priors filling you cluelessness.
Qué vergüenza. A usar dinero público para dárselo a una consultora y hacer pura basura innecesaria que no soluciona nada.
Pablo Rodríguez Mier retweeted
📹 Check out how Karenina works, our open-source framework to evaluate LLMs & agents: doi.org/10.64898/2026.09.01.…
Pablo Rodríguez Mier retweeted
How do we know whether a biomedical foundation model has learned something biologically meaningful - rather than simply learned to excel on a narrow benchmark? See our new Perspective by @JulioSaezRod and Philipp Sven Lars Schäfer with Nikolas Kalavros & Gustavo Stolovitzky
Pablo Rodríguez Mier retweeted
I am done with this shit. It is over. The state of engineering right now is horrible. It has been half a month since I started a new role at a big company. Nobody knows anything here. The specs, code, tests, PRDs, tickets, resolution of those tickets, reports, etc., everything is made by Claude Code. Nobody on my team likes this. They are being forced to ship as much as they can. I have heard multiple times from higher management that pushing code is not a bottleneck, so why are we slow? People are working 12 to 13 hours a day just to press enter. Nobody is reading anything. Humans in corporate are doing nothing on their own. Everyone, literally everyone, from an L1 to an L7 engineer here is doing the same thing. Talk to Claude. There is no sense of victory. Nobody is resolving bugs. In reality, nobody is thinking anymore. Everything is done by LLMs. It is so soul-sucking. I would not mind it, to be honest, if we were at least given the time to check out the code and see what is going where. But no, the goal is to just ship. No matter what happens.
Pablo Rodríguez Mier retweeted
Mathematics has now fully morphed into biology:
Project costs millions $ ✅
Put out paper that nobody has read ✅
Massive paper supplement nobody will read ✅
Advertise with pretty art ✅
Vicious authorship fight ✅
Say you're curing cancer ✅
Pablo Rodríguez Mier retweeted
Yale med school prof tells his postdocs: Work extra hours at my command or you’re no better than “the guy who charges me by the hour to cut my lawn.”
statmodeling.stat.columbia.e…
Pablo Rodríguez Mier retweeted
Warms my heart to see the everyone's excitement🧡
Finally people can imagine how amazing it must be to be part of this graphics team.
🔥Especially proud of VFX art who made all that effort worth it, from every big fire, splash and smoke to the wee sparks, dust and blood💥
Watch Grand Theft Auto VI: An Extended Look. Now on @netflix: netflix.com/GTAVI
ALT Grand Theft Auto 6 art featuring Jason and Lucia wearing bandanas to cover the lower half of their faces, armed with handguns. In the background, a vehicle with an open passenger door is parked at a gas station against a pink and purple sky. Under the Grand Theft Auto 6 logo, text reads: An Extended Look. Netflix. Now Playing.
Pablo Rodríguez Mier retweeted
Job Alert: A stealth startup focused on non-cancer diagnostics is keen to hire a deep learning for genomics/bio engineer. I am an advisor for the startup & closely involved. Please see the attached job description below and get in touch if interested. Please forward.
Pablo Rodríguez Mier retweeted
⬇️ Check out this new postdoctoral fellowship to be jointly hosted by Mathew Garnett's lab and our lab!
lnkd.in/p/eZUYhWmz
Pablo Rodríguez Mier retweeted
We built a joint experimental and computational platform for scalable multi-modal single-cell chemical screens — profiling RNA, protein (including phospho-signaling), and chromatin accessibility responses to thousands of small molecule perturbations in parallel. biorxiv.org/content/10.64898…
Pablo Rodríguez Mier retweeted
An important and underrated skill - learning Latin so you can mog your coworkers by prompting Claude like a wizard
Pablo Rodríguez Mier retweeted
1/🧵New preprint! We built a patient-level map of systemic lupus erythematosus using single-cell blood transcriptomics, linking multicellular immune coordination to patient heterogeneity, future disease activity, and potential tissue pathology.
➡️ doi.org/10.64898/2026.04.28.…
Now you can plot cool networks using DOT and graphviz layouts. It does not matter if graphviz is not installed, it supports native binaries, js/wasm and webassembly with wasmtime, + other nice options!
Check the @marimo_io notebook in molab: molab.marimo.io/notebooks/nb…
Pablo Rodríguez Mier retweeted
Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR.
We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets.
Thread + link below.
Pablo Rodríguez Mier retweeted
Announcing Talkie: a new, open-weight historical LLM! We trained and finetuned a 13B model on a newly-curated dataset of only pre-1930 data. Try it below!
with @AlecRad and @status_effects 🧵
Need to visualize complex graphs, trees, or workflows in Python? easydot renders Graphviz diagrams in the browser with a single line of code. No binary install required.
Plays nicely with @marimo_io notebooks too!
📦 github.com/pablormier/easydo…
▶️ demo: marimo.app/l/y20xye
Pablo Rodríguez Mier retweeted
For the first time in over 50 years, humans saw the Moon from up-close. 🌕✨ Science is beautiful!
More photos here: nasa.gov/gallery/lunar-flyby…
Pablo Rodríguez Mier retweeted
🧵 See 👇 our new preprint on shared and organ-specific gene expression programs of fibrotic diseases 🧬
📄 Paper: doi.org/10.64898/2026.03.09.…
📊 Explore the data: organfibrosis.saezlab.org/
