Associate Professor of Surgery at the Massachusetts General Hospital / Harvard Medical school. Reproductive and cancer biologist.
Massachusetts General Hospital
Joined June 2021
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PepinLab retweeted
Excited to share our lab's first preprint: we used spatial transcriptomics to dissect how aging disrupts the cycling ovary! 🧵
This was an incredible team effort w/ @jenngarrison @Tammyinlab @davidsebfischer AlisonKochersberger @RuthRaichur @sophiamszady
PepinLab retweeted
.@kristenvbrown has spent nearly a decade reporting on consumer-DNA-testing companies and has recently written about the risks of sharing your data with genetic-testing companies.
Tomorrow, she’s answering all of your questions in r/health on Reddit:
PepinLab retweeted
I will be honored to coordinate this SSR New Investigator Bootcamp webinar tomorrow discussing the leadership, mentorship, and tenure for young investigators. Welcome register and join us. We will have three great panelist members, Dr. Jodi Flaws, Ripla Arora, and Humphrey Yao.
💡 Join us for our upcoming New Investigator Bootcamp webinar on "Leadership and Mentorship for Career Advancement and Tenure."
📅 Dec 11 | 12 PM ET
🎤 Dr. Humphrey Yao, Dr. Jodi Flaws, Dr. Ripla Arora
Register today ➡️ brnw.ch/21wOUgb
#EarlyCareer #Leadership
PepinLab retweeted
Check out our new story! Mechanisms of innate and adaptive immune activation in cancer cells deficient in SMARCA4. Thank you to the multiple collaborators that made it possible. @neoviral @bengrbm @gonen_mithat @ChiappinelliLab science.org/doi/full/10.1126…
PepinLab retweeted
New paper from our group in @Nature by @YiyunLin_YL @junkewang @KaileWang and team reporting the unexpected discovery of aneuploid epithelial cells (3%) in normal breast tissues from healthy women raising the question of when is cancer really cancer?
nature.com/articles/s41586-0…
Can Women Anti-Age Their Ovaries to Live Longer? elle.com/beauty/health-fitne…
PepinLab retweeted
Today! Come join us
🌟 Join us for the New Investigator Bootcamp webinar, "How to Put the ‘Fun’ in Funding: Applying, Maintaining Grant Funds and Managing your Finances!"
📅 Nov 13 @ 12 PM ET
🗣️ Dr. Chris Geyer, Dr. Paige Cooper, Dr. Stephanie Pangas, Dr. Susan Taymans
🔗 brnw.ch/21wOjux
PepinLab retweeted
Woohoo, it's out! Our exciting publication in @PNASNews on genetic variants in kinesin genes that alter egg aneuploidy in humans. pnas.org/doi/10.1073/pnas.24…
PepinLab retweeted
Check out our most recent work published in Communications Biology on harnessing the power of an ex vivo ovulation model to define the molecular mechanisms of follicle rupture.
nature.com/articles/s42003-0…
Congratulations Emily Zaniker and team!
PepinLab retweeted
AlphaFold reveals the intimate details of the molecular meet-cute between sperm and eggs go.nature.com/3YqKdif
PepinLab retweeted
Each month an #egg is ovulated from the #ovary, starting the journey of reproduction. But how does ovulation occur?🥚
Our latest work in @NatureCellBio led by @LastChrisThomas and @Tabea_Marx, describes the control of #ovulation using live imaging.
bit.ly/3Ya8dEL (1/7)
PepinLab retweeted
Happy publication day for us! Labor of love with @CoffmanLab #TLS #ovariancancer @UPMCHillmanCC @PittTweet
The activity of tertiary lymphoid structures in high grade serous ovar... sciencedirect.com/science/ar…
PepinLab retweeted
Data integrity concerns flagged in 130 women’s health papers — all by one co-author nature.com/articles/d41586-0…
PepinLab retweeted
Making Eggs Without Ovaries, by @NikoMcCarty asimov.press/p/eggs?r=hzuy&u…
PepinLab retweeted
Excited to share my final paper as a postdoc with @NUDuncanLab, now on BioRxiv! Grateful to @GCRLE1 for funding this high-risk project and for fostering a network of reproductive biologists working on ovarian aging
biorxiv.org/content/10.1101/…
As an immigrant to the United States, along with many members of my lab, I feel compelled to reiterate that we are working on the development of non-surgical contraceptives for the humane treatment of cats, not recipes.
PepinLab retweeted
Excited to share that my latest research on rejuvenating aged oocytes has just been published in @NatureAging with @SpringerNature! 🌟 Read here:
xitter.cf/NaturePortfolio/status…
Aged mouse oocytes appear to improve their developmental potential when implanted in follicles from young mice, according to a study in @NatureAging. This research highlights the importance of the follicular microenvironment in ovarian aging. go.nature.com/3MCn1Xp
ALT This is figure 6, which shows restored mitochondrial fitness in aged oocytes cultured in young r-follicles.
PepinLab retweeted
Hormone-free infertility treatment....well, here we are finally...it's a clinical reality!! 20 years ago, our old IVM alliance: myself, @jeremygthompso2, Johan Smitz and @MdevosMD made this our aspirational goal. Now Dr Lan Vuong and @TuongMHo got there!!
PepinLab retweeted
The end of menopause: would women be healthier and happier if they menstruated for ever? | Menopause | The Guardian theguardian.com/society/arti…
Great summary of the inflated expectations of age reversal. It’s certainly true of reproductive aging. How can anyone make claims when we barely understand the fundamentals. embopress.org/doi/full/10.10…
