@PetzoldKatja

RNA moving with atomic resolution, what’s next? (Professor @UU_University)

 Uppsala, Sweden
petzoldlab.com
Joined May 2017
  • Tweets5K
  • Following1.1K
  • Followers1.6K
67Media
📷 Interested in computational #NMR ? Join us in beautiful Switzerland in June! Many slots for selected talks and great hiking opportunities. #GRC conference 1-6th of June with GRS (@chrisdkolloff and Stase) on 30.05. please share @nmr900 grc.org/computational-aspect…
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Imagine if one of #RNA’s most common 3D contacts can switch off and on. We identified the A-minor switch that reversibly “escapes” their tertiary contacts, revealing a regulatory layer (by #NMR & #CryoEM and assayed in #ribosomes). #dynamics lnkd.in/exRWJQJY
🤖 Made with AI
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MicroRNA rock 🎊🥳🎉 naturvetarna.se/nyheter/2024…
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Hanging out with the lovely ladies of structural bio!!! @DJanuliene @PetzoldKatja We love RNA, too 😍 because the best mmmmmRNAs end up as membrane proteins 😉 #MurnauStructuralBiology @GBM_eV
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Amazing organisation for the @ICMRBS #NMRchat #ICMRBS in Seoul. We learned a lot from the Korean organization team and are looking forward to see you at the ICMRBS 2026 in Davos Switzerland. Mark it in your calendar!
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Amazing to be at the @ICMRBS #ICMRBS2024 in Seoul! Great conference. Plus Henry’s paper on optimizing in-cell NMR just got out link.springer.com/article/10…

Optimising in-cell NMR acquisition for nucleic acids

Journal of Biomolecular NMR - Understanding the structure and function of nucleic acids in their native environment is crucial to structural biology and one focus of in-cell NMR spectroscopy. Many...

link.springer.com
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Cool paper! Congratulations 🎉
Wilhelmsson Lab@WilhelmssonLab20 Aug 2024
Is metabolic fluorescence labeling of RNA in non-engineered cells possible? Yes it is! Very happy about this one: doi.org/10.1093/nar/gkae722 @OUPAcademic

Metabolic RNA labeling in non-engineered cells following spontaneous uptake of fluorescent nucleo...

Abstract. RNA and its building blocks play central roles in biology and have become increasingly important as therapeutic agents and targets. Hence, probin

academic.oup.com
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really nice paper from Ann McDermotts Lab: pubs.acs.org/doi/10.1021/acs…

Predicted and Experimental NMR Chemical Shifts at Variable Temperatures: The Effect of Protein...

Abstract. NMR chemical shifts provide a sensitive probe of protein structure and dynamics but remain challenging to predict and interpret. We examine the e

pubs.acs.org
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Our single particle profiler is now more accessible! If you have a confocal microscope, you can study the content and properties of single particles thanks to the open and freely available single particle profiler (with easy GUI).👇 for detailed thread biorxiv.org/content/10.1101/…

Imaging single particle profiler to study nanoscale bioparticles using conventional confocal...

Single particle profiler is a unique methodology to study nanoscale bioparticles such as liposomes, lipid nanoparticles, extracellular vesicles and lipoproteins in single particle and high throughput...

biorxiv.org
Taras Sych@SychTaras28 Jun 2024
We continue development of our Single Particle Profiler and now we make it more accessible for users who do not have FCS modality on their microscopes. biorxiv.org/content/10.1101/… A thread🧵
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Want to work interdisciplinary? Postdoc and Research Coordinator @ Center of Excellence “Chemical Mechanisms of Life" Uppsala, Sweden - please share: jobb.uu.se/details/?position… jobb.uu.se/details/?position…
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Increase this year (maybe somewhat overestimated) fastighetsvarlden.se/tag/hyr… (for the general market)

Hyresförhandlingar 2024 | Fastighetsvärlden

fastighetsvarlden.se
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scb.se/hitta-statistik/stati…. Last years rent increase
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Swedish universities are bled dry by the rent taken from the government owned agency Akademiska Hus, rent increased 17% in the last two years with no increase in base funding. (Average increase ~9%) svt.se/nyheter/lokalt/uppsal…

Uppsala universitet pressat ekonomiskt – tvingas tömma lokaler och ställer in föreläsningar

Ett nytt ekonomiskt läge tvingar Uppsala universitet att anpassa undervisningen. Verksamheter krymper, labbytor stänger och föreläsningar ersätts av seminarier. Anledningen är att Akademiska hus, som...

svt.se
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Pleased to share our new article "A new reagent for in vivo structure probing of RNA G and U residues that improves RNA structure prediction alone and combined with DMS" out in @RNAJournal. Collaboration with @BabitzkePaul.
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Only two days left to put in your application for the NMR EMBO practical course in Grenoble this summer: meetings.embo.org/event/24-n…

Structure, dynamics and function of biological macromolecules by NMR

NMR spectroscopy is an essential technique that allows to study the structure, dynamics and interactions of macromolecules at atomic resolution. It is unique in extracting dynamic information over a …

meetings.embo.org
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So much junk journals! It's impossible to keep track. We need a "positive" list of journals, that are, according to scientists, legit. These are the only ones that should be counted for citations and research. Does anyone know of such? @MicrobiomDigest? University libraries?? RT
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I'm going to start a new hashtag to show cases where universities or journals have been notified of severe (image) concerns years ago, but have not taken any action. I will name and shame, because it's frustrating and maddening. #IntegrityInertia
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Wow!! Big congratulations Hashim! Well earned!!
Qi Zhang Lab@QiZhangLab8 Apr 2024
Huge congratulations to Hashim M. Al-Hashimi @ColumbiaBiochem for receiving The 2024 Laukien Prize @ENC_Conf !!!
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My first postdoctoral paper from @PetzoldKatja lab is now online in bioRxiv. We show how microRNA-34a is organised in Argonaute-2 using DNP MAS #NMR. We also observed different dynamic states of miR-34a due to high resolution and enhancement. biorxiv.org/content/10.1101/…

Elucidating microRNA-34a organisation within Human Argonaute-2 by NMR

Understanding mRNA regulation by microRNA (miR) relies on the structural understanding of the RNA-induced silencing complex (RISC). Here, we elucidate the structural organisation of miR-34a, deregu...

biorxiv.org
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I am recruiting a postdoc to work on RNA binding proteins. Read more details in the link below. nature.com/naturecareers/job…

Postdoctoral fellow to study RNA binding proteins - Gothenburg (Stad), Västra Götaland (SE)

Postdoctoral fellow to study RNA binding proteins

nature.com
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We have been busy and working to understand microRNA down-regulation beyond the seed. Lara Sweetapple's and colleagues contribution together with the E.R Andersson and A. Chen labs biorxiv.org/content/10.1101/…

Biophysics of microRNA-34a targeting and its influence on down-regulation

microRNAs (miRNAs) regulate target mRNA expression post-transcriptionally through their association with Argonaute 2 (AGO2) proteins. Predicting the efficiency of mRNA repression by miRNA has been...

biorxiv.org
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