A neuroengineering lab at Stanford University focused on brain dynamics, brain health, and the neural mechanisms of anesthesia.
Stanford School of Medicine
Joined June 2020
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The PurdonLab retweeted
After 4 years of traveling between Harvard/MIT and Stanford and 200 pages of utter despair aka my thesis, I have officially defended my PhD in Medical Engineering and Medical Physics through the Harvard/MIT Health Sciences and Technology Program!
The PurdonLab retweeted
Can brain waves during surgery predict who’s at higher risk after?
What’s going on:
Every year, millions of people die after surgery. Doctors need better ways to spot who’s most at risk—while the surgery is happening.
The PurdonLab retweeted
Link to full article: journals.lww.com/anesthesiol…
The PurdonLab retweeted
Thanks to everyone in the @PurdonLab @RyanNipp @BalanzaGus @rggutierrez1 @Ran_Liu_16 and teams at @MGHanesthesia @stanfordanes who helped contribute to this work!
The PurdonLab retweeted
Excited that my first 1st authored paper from my PhD research has been published in Anesthesiology!
We found that neural oscillations in the alpha band of frequencies (8-12 Hz) during anesthesia can predict the risk of postop mortality up to a year after surgery. 🧵 (1/3)
The PurdonLab retweeted
Excited that our case report has been published!
Here we show how the neural signals from a readily available forehead EEG sensor can be used to titrate anesthetic dosing for a child with neurodegenerative disease and decrease postop recovery times.
journals.lww.com/aacr/fullte…
The PurdonLab retweeted
Excited to share the results of yrs of data collection @CharlesaNelson1‘s lab & great collab w/ @Lisa_Yankowitz @JerryChaoMD @rggutierrez1 & @PurdonLab.
Developmental trajectories of EEG aperiodic and periodic components in children 2-to-44 months of age.
rdcu.be/dNj0I
The PurdonLab retweeted
Enjoying our @UWAnesthPainMed 16th Academic evening in the beautiful UW WƎⱢƎBʔALTXʷ – Intellectual House: a huge display of the rich science that our departmental members pursue in biomedical & clinical sciences. Our 🔑 note speaker is Dr. Patrick Purdon from @stanfordanes
The PurdonLab retweeted
Another publication in the books!
We use a machine learning model only using diagnosis and procedure codes before surgery to predict patients’ postop mortality and adverse outcomes.
Thanks to @Ran_Liu_16 @PurdonLab for letting me join this project!
sciencedirect.com/science/ar…
The PurdonLab retweeted
Multicenter EHR data from >234k adult non-cardiac surgical patients is used to predict maximum pain after surgery.
This #MachineLearning model prospectively outperformed clinicians, & can identify comorbidities that drive postoperative pain.
nature.com/articles/s41746-0…
The PurdonLab retweeted
Excited to share that my first paper of grad school was just published in Nature Partner Journal: Digital Medicine: nature.com/articles/s41746-0…
Thanks to everyone @MGH_PurdonLab and the first authors @rggutierrez1 @Ran_Liu_16 for giving me the chance to be a part of this project!
The PurdonLab retweeted
New article! Read Development and prospective validation of postoperative pain prediction from preoperative EHR data using attention-based set embeddings dlvr.it/SyvzrG in npj Digital Med
The PurdonLab retweeted
NEW STUDY of 60k+ Surgical Patients: Greater use of intraoperative fentanyl & hydromorphone associated with decreased new chronic pain diagnoses at 3 months and decreased post-op persistent opioid use without significant increases in adverse events jamanetwork.com/journals/jam…
The PurdonLab retweeted
In this study, intraoperative opioid administration was associated w short- and long-term postoperative pain and opioid outcomes; reduced opioid administration during surgery may have the unintended outcome of increasing postoperative pain and opioid use. ja.ma/43WFTXU
The PurdonLab retweeted
Deadliness associated with #DrugMisuse of #fentanyl explained by its causing breathing to stop before sedation kicks in, say researchers from the department of anesthesia of the Massachusetts General Hospital bit.ly/3BfpItq
The PurdonLab retweeted
The association between injurious falls and older adults’ cognitive function: the role of depressive mood and physical performance.
academic.oup.com/biomedgeron…
#Geriatrics #Cognition #Aging #GeriOnc
@geronsociety @MGH_PurdonLab @APOSHQ
The PurdonLab retweeted
Thank you @IARS_Journals for sharing our work, at @MGH_PurdonLab, with the society; Brain oscillatory states could link the neurobiological processes at the cellular level to the cognitive level! 〰️🧠
🔴 Intraop burst suppression & postop delirium are correlated-authors showed low anesth-induced frontal alpha power associated with burst suppression, independent of age: low frontal alpha power could be a marker of a “vulnerable brain” @ka_pegah @_RayShao journals.lww.com/anesthesia-…
The PurdonLab retweeted
🔴 Intraop burst suppression & postop delirium are correlated-authors showed low anesth-induced frontal alpha power associated with burst suppression, independent of age: low frontal alpha power could be a marker of a “vulnerable brain” @ka_pegah @_RayShao journals.lww.com/anesthesia-…
The PurdonLab retweeted
Though blood pressure and muscle relaxation are monitored intraoperatively, even for children, it's the brain that is the primary site of action. The authors describe #EEG signatures seen in adults that are also seen in children #pedsanesth @pedianesthesia journals.lww.com/anesthesia-…
The PurdonLab retweeted
Our broadband paper is out in Scientific Reports! nature.com/articles/s41598-0…
Happy to announce that we've posted our new preprint "Broadband slow-wave modulation in posterior and anterior cortex tracks distinct states of propofol-induced unconsciousness" (1/3): biorxiv.org/content/10.1101/…
