@NDMOxford DPhil| Erasmus Vaccinology MSc| @DukeU BS| @ArtisVentures Fellow, Computational vaccinology enthusiast š¾ SLO CD8 T cell diversity
Oxford, UK
Joined July 2017
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Interested in learning about how some cool follicular T cells modulate B cell and antibody responses in #hooman ? PM me š¤£šš« #vaccinology #immunology #computationalimmunology #bluedevils #follicularTcells
I am no longer active on social media. Reports of my accounts being hacked have been noted. Please always reach out face-to-face as needed regarding any suspicious message.āŗļø
Following suit, I too will no longer be on the dark X -- Plz join me (quang-n-nguyen.bsky.social) catching butterflies on @bluesky
The chatter is becoming very noisy and I canāt learn as much science here compared to before.
Will be off from the blue bird (or the dark X).
You can find me on BlueSky bsky.app/profile/tsanglab.bsā¦.
quang-n-nguyen.bsky.social retweeted
šØš¦ expat living in šŗšø. Got PhD in the šŗšø and stay as I love the people and the innovative spirit of this country. Long had a green card but became a citizen after the previous president said he could kick us out. I voted today for the first time to ensure that won't happen again.
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Brain tumors hijack neural language circuits to fuel their growth š³
nature.com/articles/s41586-0ā¦
quang-n-nguyen.bsky.social retweeted
Really cool paper: refueling T cells by sending mitochondria via a tunnel empowers the T cells to fight tumors better.
cell.com/cell/fulltext/S0092ā¦
FDCs, Tfh/Tfr, and B cells, NK cells, et al. but there is always a place for something else -- a tingible body macrophages that autocorrect will continue to fix into tangible. š
#germinalcenters #follicular #humoral #vaccinology
annualreviews.org/content/joā¦
Non-resolving inflammation can induce "bad" lymphoid rxns, leading to dysregulation of host defense & pathogenic autoreactivity. But not in all #autoimmunedisease & cancer patients #Tfh #Tfr #GCreactions
nature.com/articles/nri3700
quang-n-nguyen.bsky.social retweeted
Excited to share our new paper on temporal analysis of vaccine+/- adjuvant hours to 100 days (14 time pts). Vax alone induces new baseline immune state early & persists to 100 days, and that state predicts vax responses in an indep cohort. cell.com/cell-reports/fullteā¦.
Adaptive and innate immune cell diversity and composition underlying #immunevariations between human populations, and how they are influenced by both host genetics and non-genetic factors. Quite an insightful read on #systemsimmunology w historical touch
cell.com/cell/fulltext/S0092ā¦
quang-n-nguyen.bsky.social retweeted
Mapping cellular interactions from spatially resolved transcriptomics dataš nature.com/articles/s41592-0ā¦
"Several HLA haplotypes, some of which encode ligands for natural killer cell receptors (KIRs), were acquired through admixture with Denisovans or Neanderthals." š #introgression cell.com/cell/fulltext/S0092ā¦
quang-n-nguyen.bsky.social retweeted
What if we could map every cell in the body, revealing its location and molecular identity? In this @NatureMethods perspective, we discuss the new era of 3D-omics by tissue clearing and AI, called Deep 3D Histology: rdcu.be/dNBe8 PDF: bit.ly/3WaD0QU š§µšš¼
quang-n-nguyen.bsky.social retweeted
Directly selecting cell-type marker genes for single-cell clustering analyses
cell.com/cell-reports-methodā¦
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Single cell profiling is costly and not yet scalable across large population cohorts. Here an interesting āsemi-profilingā approach combines active learning and deep generative models to improve cell type decomposition from bulk data ā¦@NatureCommsā© nature.com/articles/s41467-0ā¦
quang-n-nguyen.bsky.social retweeted
Love Immunology? Hate Cancer?
Come join the Centre for Immuno-Oncology as a senior postdoc in Immunopeptidomics.
jobs.ac.uk/job/DIT166/seniorā¦
quang-n-nguyen.bsky.social retweeted
Extremely proud and excited to share my thesis work from the Choi lab @jaehyukchoimd, in collaboration with @Deepakarao and @@vwacle, online today @Nature where we investigate pathological CXCL13+ Tph cell circuitry in SLE, online here:nature.com/articles/s41586-0ā¦
quang-n-nguyen.bsky.social retweeted
Stanford Medicine is making a large investment to hire multiple faculty in AI/ML. I'm one of the co-chairs. If you have questions, do not hesitate to reach out: facultypositions.stanford.edā¦
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š¢Hot off the press: our review on "tissue active matter"
Together with @EdouardHannezo, we review theoretical approaches for tissue dynamics, integrating active mechanics, cell-cell interactions and biochemical signaling
Now out in CSH Perspectives:
ā”ļøcshperspectives.cshlp.org/coā¦
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R package to query the Human Cell Atlas at the tissue, condition or sample level
stemangiola.github.io/Curateā¦
quang-n-nguyen.bsky.social retweeted
Want to analyze Single cell, Multiomics, Spatial or ATAC-seq data but don't know where to start? Or do you face problems in analysis ? Fret not, we have a solution for you. Our lab has developed ezSingleCell - nature.com/articles/s41467-0ā¦
