This paper is a goldmine on scientific self-experimentation. -14 Nobel Prizes have gone to self-experimenters. - Of 465 scientific self-experiments documented over a 203-year period, there have been 8 deaths. - The most recent recorded death from a self-experiment was in 1928, when Alexander Bogdanov injected himself with an incompatible blood type. - Many universities say that self-experimentation would require IRB approval because it violates "ethical norms for medical research," which is not true; the Nuremberg Principles make an explicit exception for people experimenting on themselves, and the Declaration of Helsinki just says the subject must consent. Also, "there is no law nor regulation identified that requires investigators experimenting on themselves to consult an ethics committee." - There are lots of recent self-experiments; "In 2014, Philip Kennedy had electrodes implanted into his speech center to further his research on direct brain interfaces. In 2016, Alex Zhavoronkov self tested drugs which his software algorithms identified as likely candidates."