Janane F. Rahbani (@RahbaniLab) header
Janane F. Rahbani (@RahbaniLab) profile picture

Janane F. Rahbani

@RahbaniLab

Assistant Professor of Medicine- UChicago Hematology/Oncology @UChicagoHemOnc @uchicago. Beyond the Scale: Tackling Obesity, Conquering Cancer

 Chicago, IL.
jananerahbanilab.com/
Joined September 2012
  • Tweets138
  • Following226
  • Followers327
Janane F. Rahbani retweeted
Caner Saygin, MD (@CanerSaygin) profile picture
Caner Saygin, MD@CanerSayginSep 1
Voting has started for #ASH26 elections. We are rooting for Wendy Stock @DrWendyStock running for Vice President! She is an incredible hematologist, researcher, mentor, sponsor and advocate. She made enormous impact on so many lives and careers, including mine. So please vote!
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Janane F. Rahbani retweeted
Lawrence Kazak (@kazaklab) profile picture
Lawrence Kazak@kazaklabApr 22
For 40+ years, we’ve known how UCP1 drives thermogenesis—but how UCP1-independent pathways are activated remained unknown. Thrilled to share our @Nature paper, led by Faiz Hussain, uncovering this mechanism: nature.com/articles/s41586-0…
Glycerol-driven TNAP activation in thermogenesis and mineralization

Glycerol-driven TNAP activation in thermogenesis and mineralization

Nature - Glycerol is an allosteric activator of tissue-nonspecific alkaline phosphatase (TNAP), activating the futile creatine cycle.

nature.com
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New PhD opportunity at TUM!
Image from Martin Klingenspor (@MartinKlingens4)
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Janane F. Rahbani retweeted
Kunle Odunsi, MD (@KunleOdunsiMD) profile picture
Kunle Odunsi, MD@KunleOdunsiMD29 Jul 2025
I’m proud of @UCCancerCenter’s national ranking in the top 1% and #1 in Illinois. It is a testament to our exceptional patient-centered care and innovative research. We are reshaping the future of cancer care @KunleOdunsiMD #NothingWillStopUs
Image from Kunle Odunsi, MD (@KunleOdunsiMD)
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🔥 Hot off the press: In a new @Nature study, @ErnstLengyel and team show that blocking NNMT in tumor-supporting cells restores immune response & stops ovarian cancer growth, offering a new strategy for hard to treat cancers. @OvCa_UChicago @uchicago_obgyn ow.ly/zzfZ50Wu3UW
Image from UChicago Medicine Comprehensive Cancer Center (@UCCancerCenter)
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Janane F. Rahbani retweeted
Lawrence Kazak (@kazaklab) profile picture
Lawrence Kazak@kazaklab4 Jul 2025
New paper from @BunkJakub and Mina Ersin in our lab: CKB is the key creatine kinase driving UCP1-independent #thermogenesis in beige fat via the futile creatine cycle (FCC). doi.org/10.1016/j.molmet.202… @McGillGCI @McGillBiochem @MolMetab
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Janane F. Rahbani retweeted
Lawrence Kazak (@kazaklab) profile picture
Lawrence Kazak@kazaklab4 Apr 2025
Today in @NatureComms, we show the #FutileCreatineCycle plays a key role in #thermogenesis, independent of UCP1. We also challenge the belief that brown adipocytes lack enough ATP synthase for thermogenesis. Congrats @BunkJakub! Full paper: rdcu.be/egoV7 @McGillGCI
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Janane F. Rahbani retweeted
Lawrence Kazak (@kazaklab) profile picture
Lawrence Kazak@kazaklab1 Jan 2025
It’s finally here! Check out our website for the Adipose Biology Conference: adiposebiology.com/registrat… with @beaudrj & @sung4400, partnered with @SableSys! Amazing speakers. Registration is now open!! 📍Montreal, Canada 📅Aug 19-20, 2025 #adiposebiology

Registration | Adipose Biology

adiposebiology.com
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Janane F. Rahbani retweeted
Lawrence Kazak (@kazaklab) profile picture
Lawrence Kazak@kazaklab30 Nov 2024
I'm thrilled to co-organize the inaugural #AdiposeBiology Conference with @beaudrj, @sung4400, and @SableSys! 📍Montreal, Canada 📅Aug 19-20, 2025 Registration opens Jan 1, 2025. More info in the coming weeks. Hope to see you there! @AdiposeBiology #AdiposeBiology2025
Image from Lawrence Kazak (@kazaklab)
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Our new paper, "NK2R control of energy expenditure and feeding to treat metabolic diseases," is out today in @Nature. Here we identify a single receptor that can both peripherally increase energy expenditure and centrally suppress appetite. nature.com/articles/s41586-0… 1/12 🧵👇
NK2R control of energy expenditure and feeding to treat metabolic diseases

NK2R control of energy expenditure and feeding to treat metabolic diseases

Nature - In mouse and nonhuman primate models, treatment with selective, long-acting neurokinin 2 receptor agonists aids weight loss by suppressing appetite and increasing energy expenditure, as...

nature.com
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Janane F. Rahbani retweeted
Muir Lab (@Muir_Lab) profile picture
Muir Lab@Muir_Lab17 Sep 2024
Research Scientist position is open @ the UChicago Metabolomics Platform. Exciting position to work with cutting edge instrumentation to perform metabolomics, lipidomics and stable isotope tracing experiments! Please RT and forward onto anyone interested! uchicago.wd5.myworkdayjobs.c…
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Janane F. Rahbani retweeted
Lawrence Kazak (@kazaklab) profile picture
Lawrence Kazak@kazaklab5 Sep 2024
Hello #thermogenesis and #adipose folks, Ucp1 lovers and non-canonical lovers: Our recently generated Ucp1 and Ckb conditional mice will soon be available at The Jackson Laboratory: jax.org/strain/039540 jax.org/strain/039539
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Janane F. Rahbani retweeted
Simon Schwörer (@schwoerersimon) profile picture
Simon Schwörer@schwoerersimon17 Aug 2024
Excited to share the first paper from the lab @UChicago! In this review, @juguillard and I discuss how nutrient availability and utilization regulate collagen synthesis in heath and disease, and propose underlying metabolic networks. sciencedirect.com/science/ar…
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Janane F. Rahbani retweeted
Spiegelman Lab (@LabSpiegelman) profile picture
Spiegelman Lab@LabSpiegelman30 Jul 2024
Here is our new paper showing that beige fat cells occur in 2 major types: UCP1-high and Futile creatine cycle (FCC)-high. This kind of reconciles the UCP1 vs FCC discussions. authors.elsevier.com/a/1jWGh…
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Janane F. Rahbani retweeted
Lawrence Kazak (@kazaklab) profile picture
Lawrence Kazak@kazaklab14 Jun 2024
Tenured. Thanks to all Kazak lab members - past and present - for their hard work, curiosity, and trust in the scientific process. Thanks to @Parklabmcgillu and @thomas_duchaine for their leadership. And thanks to the anonymous letter writers. @McGillGCI @mcgillu
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Janane F. Rahbani retweeted
Kunle Odunsi, MD (@KunleOdunsiMD) profile picture
Kunle Odunsi, MD@KunleOdunsiMD1 Apr 2024
I’m thrilled to announce that @theNCI renewed our designation as a Comprehensive Cancer Center for the high-impact work we do for cancer patients and the community. ow.ly/HUOc50R5Jut #NothingWillStopUs #WeAreNCIDesignated #UChiCancer50 @KunleOdunsiMD
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Janane F. Rahbani retweeted
Lawrence Kazak (@kazaklab) profile picture
Lawrence Kazak@kazaklab9 Mar 2024
Check out the recent Preview @Cell_Metabolism on our recent work demonstrating a major role for CKB and UCP1 working in parallel to promote most of adipocyte thermogenesis: sciencedirect.com/science/ar…
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Janane F. Rahbani retweeted
Spiegelman Lab (@LabSpiegelman) profile picture
Spiegelman Lab@LabSpiegelman21 Dec 2023
Are you passionate about molecular metabolism? Do you love working with a dynamic team of scientists? Do you crave epic fishing stories? If you answered yes (and have a BA/BS in science) we have an opportunity for you! Spiegelman lab is hiring a research technician!
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Janane F. Rahbani retweeted
Vera Pieters, PhD (@VeraPieters_) profile picture
Vera Pieters, PhD@VeraPieters_30 May 2023
TOMORROW! -Adipose Biology Seminar Series- ⏰May 30, 12pm-1pm EST 🎙️Assistant Professor @ShannonReilly5 from @WeillCornell 💻Details on poster below 🌱Kindly supported by @MbD_UofT Please retweet! Contact us to present in a trainee seminar? ⭐️
Image from Vera Pieters, PhD (@VeraPieters_)
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Janane F. Rahbani retweeted
Vera Pieters, PhD (@VeraPieters_) profile picture
Vera Pieters, PhD@VeraPieters_22 Mar 2023
NEXT WEEK! -Adipose Biology Seminar Series- ⏰March 28, 12pm-1pm EST 🎙️Professor @Z_GerhartHines from @Metabolcenter at @koebenhavns_uni 💻Details on poster below 🌱Kindly supported by @MbD_UofT Please retweet! Students/PDFs: Want to present in a trainee seminar? Contact us!⭐️
Image from Vera Pieters, PhD (@VeraPieters_)
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