Mucosal immunology lab @ UMass Chan Medical School.

Worcester, MA
Joined November 2018
.@ReboldiLab, @BucciVanni et al. reveal that #microbiome-driven tuft cells’ hyperplasia in the colon helps defend against Clostridioides difficile infection. hubs.la/Q036Gplq0 📘 In Host–Microbe Interactions 2025 👉 hubs.la/Q036GsWl0 #KSHumanMicro25 #KSHostMicrobe25
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Toronto-based ImmVue Therapeutics Inc. has licensed a potential @UMassChan cancer therapeutic for clinical development: direc.to/m4zF This partnership was facilitated by BRIDGE Innovation and Business Development at UMass Chan. @immvue @CUMedicalSchool
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In @JExpMed, @ReboldiLab @BucciVanni et al. reveal that #microbiome-driven tuft cells’ hyperplasia in the colon helps defend against Clostridioides difficile infection, providing a pathway thru which host & microbial interactions protect against pathogens hubs.la/Q02ZBWxx0
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Katalin Karikó and Drew Weissman – awarded the 2023 #NobelPrize in Physiology or Medicine – discovered that base-modified mRNA can be used to block activation of inflammatory reactions and increase protein production when mRNA is delivered to cells.
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Scientists led by Dr. Andrea Reboldi (@ReboldiLab) at @UMassChan have shown that antigen receptor signaling and cell death resistance control intestinal humoral response zonation. 📙 Study: bit.ly/48wDje6 🎧 Episode: bit.ly/3Pzas05
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Fantastic work led by @FigHumph. More ways to target STING a central node in inflammation.
#newscience alert! @fitzgeraldkate @pthompsn1018 & Dr. Shaffer collaborated to ID a compound that could be used to treat #AutoImmuneDisease !!! Check it out! @pnasnews pubmed.ncbi.nlm.nih.gov/3754…
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And the @ReboldiLab are looking for postdocs interested in studying lymphocyte immuno-metabolism at muco-cutaneous barriers, but position for bestest postdoc already taken 🐕
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Food for thought in seminar today by @ReboldiLab. IgA influences B cell competition in germinal centers of Peyer's patches. ⬆️ BCR pro-survival signaling gives IgA+ B cells an advantage ➡️ broader IgA specificity but tighter control of IgG affinity & specificity via competition.
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Reboldi Lab retweeted
IMMOX'23 - Immunology across Time and Space , Oxford, UK, 10-12 September 2023. Earlybird registration now open! Visit our website at: immox23.com for full details including speaker affiliations and bios. @MRC_WIMM #immox23 #immunology #Oxford
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Little immunologists growing 🧪🧫🔬. Thanks @ImmunologyAAI #AAI2023 for offering free daycare and Patti&Karen @KiddieCorp for taking such good care of Noah! See you next year.
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Looking forward to share new cool data on gd T cell development. Curious? Come to my talk on Sunday morning at the “Developing your Bloody Immune System” #AAI2023 #immunology2023
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Reboldi Lab retweeted
We guarantee you a brilliant line up of speakers that will bring you key concepts in mucosal immunology and the latest advances in field. It was a pleasure to put this program together with @ReboldiLab @pabloromagnoli @GutOrganoid More information coming soon…
SAVE THE DATE! SMI's Principles of Mucosal Immunology Course - June 27-29, 2023. Registration coming soon for this virtual course focusing on both scientific and career development topics facilitated in three hour segments each day.
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Work from SMI member Andrea Reboldi @ReboldiLab published in @ImmunityCP on skin γδ T cell development show a requirement for oxysterol sensing through GPR183 in the thymus as well as the periphery for homeostasis. Read more: bit.ly/3ld9A6s
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The Raffatellu lab #UCSD is hiring! We have openings for a postdoctoral fellow and a research technician - ads to be posted soon, but please contact me if interested! We are a fun, diverse group and our trainees move on to amazing careers in industry, academia, grad/med school.
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How does dietary #cholesterol affect immune responses in the gut? The @ReboldiLab identified an immune-metabolic circuit 🔁 between intestinal #epithelial cells and IgA-secreting plasma cells. 📌 @NatImmunol: go.nature.com/3X0NmRG 🎙️ bit.ly/3WX1Ty3
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Immunology seminar on Mon. Jan. 9
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