🇨🇵 PhD student in the Fre lab at Institut Curie | Tissue morphogenesis & Fate specification in glandular epithelia. Alumni @ENS_ULM & @AgroParisTech. 🎾
Paris, France
Joined December 2021
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The last version of our work is now out!
We reveal how 4 branched epithelia—mammary, lacrimal, salivary & prostate—use a conserved YAP–Notch–p63 circuit to self-organize during development & regeneration.
authors.elsevier.com/c/1lM28…
Work done in @slvfre lab at @institut_curie
Online now: Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during development and regeneration dlvr.it/TLdxyz
Robin Journot 🔬| 🎾 retweeted
Congratulations to @ChenJiang919 @yura__song and @Alessia100nze the first authors for their amazing work. A big thank to our collaborators @TheLutolfLab and Alejandro Sifrim for their precious help. nature.com/articles/s41467-0…
Robin Journot 🔬| 🎾 retweeted
our new preprint is live – check out our nifty MAGIC matrices! (1/7) doi.org/10.1101/2024.02.01.5…
Robin Journot 🔬| 🎾 retweeted
Do you want to grow 3D epithelia ex vivo long-term (~1 year) without passaging them? Check out epitheliods! nature.com/articles/s41588-0…
Excited to have shared the journey with two great scientists @AlbertHerms and @AntoranLab and the Phil Jones' team. Image credit to @MTBejar.
It was a great pleasure to share with you these three years @JakubSumbal! A brilliant defense like the rest of your work. Wishing you all the best for your future adventures 🇩🇪
You rock 👍
PhD thesis defense of @JakubSumbal is starting! Watch it now! espci.zoom.us/j/83742547728?…
#fibroblasts #mammarygland
Robin Journot 🔬| 🎾 retweeted
Excited to share our new bioRxiv preprint: Isotonic and minimally invasive optical clearing media for live cell imaging ex vivo and in vivo.
biorxiv.org/cgi/content/shor…
Promising science and great discussion condensed into an intense journey! Huge thanks to @kim_bak_jensen, @martt1m, Phil Seymour at @reNEW_Global for their time, @slvfre for the support, and @EMBO for the exchange fellowship. Excited for what’s next!
Robin Journot 🔬| 🎾 retweeted
Ever wondered how stem cells ensure a balance between cell fates in the gut?⚖️Turns out, they’ve got rhythm!🎶Our latest research reveals that NOTCH-driven oscillations regulate stem/progenitor cell abundance and specify secretory subtypes. Check it out: biorxiv.org/content/10.1101/…
Robin Journot 🔬| 🎾 retweeted
New preprint: We have developed an integrated pipeline to i) image gastruloids in toto with dual-view 2-photon🔬, ii) quantitatify cell and tissue-scale patterns of gene expression and morphometric features, iii) interact with the data in @napari_imaging. biorxiv.org/content/10.1101/…
Robin Journot 🔬| 🎾 retweeted
⏰ Last days to register to the Developmental Biology international course at @institut_curie! Discover full program, proposed in 2 versions long/short, and dive into a comprehensive coverage of the paradigms of modern Developmental Biology.
➡️ training.institut-curie.org/…
Happy to see enthusiasm for our work! 🎊
Last part of our communication:
#YAP, #Notch and #p63 regulate the self-organization of 4 different bilayer epithelia.
💭But, what did we learn conceptually? 💭
biorxiv.org/content/10.1101/…
Work by @slvfre team at @institut_curie
#PreprintAlert 🚨🚨🚨 Please RT!
Latest #Stemcell #DevBio and #Regeneration story by @SilviaFre lab at @InstitutCurie. #YAP #Notch #p63
Link: tinyurl.com/2uspcd3u
We reveal how 4 (!) epithelia self-organize during embryonic development and regeneration.
A thread🧵...
I would like to thank all the @slvfre team, particularly my bench mate @JakubSumbal for the great discussions, but also @EdouardHannezo, @bellaiche_y and Prof. Michel Labouesse for their advice as member of my PhD committee.
This work was funded by @institut_curie, @CNRS, @PSL_univ, @AgenceRecherche, @FRM_officiel, @CercleFSER, @FondationARC, @WorldwideCancer and @DeepLabex.