@RoyNgLab

Lecturer in neuroimmunology at University of Manchester

Joined May 2023
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  • Following56
  • Followers32
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Thrilled to share our latest research in @CellReports! We reveal the crucial role of fatty acid synthesis & palmitoylation in NLRP3 inflammasome activation. @imperialcollege @ImperialInfect cell.com/cell-reports/fullte…

Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation

NLRP3 is a pivotal sensor that assembles an inflammasome in response to diverse stimuli. Leishman et al. demonstrate that FASN-dependent NLRP3 palmitoylation is a prerequisite for inflammasome...

cell.com
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The Brain Inflammation Group is taking on the Yorkshire Three Peaks Challenge on April 15th to raise funds for @NKMTrust, a wonderful charity that supports essential brain haemorrhage research. Please help us reach our target by donating here: justgiving.com/page/brain-in…
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Want to know more about NF2-Related Schwannomatosis? Check out this new 26-minute podcast on this rare genetic condition, featuring BIG lab member @GraceGregory_ 🎧🧬 Watch: youtu.be/57BYRMiirIs?si=vhAl… #NF2 #Schwannomatosis #raredisease @UoMFBMH

Understanding NF2 with Grace Gregory and Gareth Evans

Bradley Findlay is a final year Biomedical Sciences student. As par...

youtube.com
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A fascinating seminar today from visitor Dr Kim Chow of @CUHKofficial. Huge thanks to @RoyNgLab and everyone who attended! 🧠 #neuroscienceseminar #manchesterneuroscience #alzheimersdisease
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What Alzheimer noted as fat saccules in glia may have been lipid droplets. They can be induced by Abeta in microglia leading them to release factors that damage neurons. ApoE4 makes things worse rdcu.be/dA6Kh. Congrats @Michael_S_Haney @robipalo and fantastic team
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Come find us at the Central Library in Liverpool to learn more about dementia! We have games & activities for all ages from little ones to adults 🧠🎲 Here until 4.30 #publicengagement #dementia @ARUKscientist @ComorbidCath @AlzResearchUK
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The next talk in our seminar series is on Weds 20th March at 2pm, presented by Dr Kim Chow from @CUHKofficial hosted by @RoyNgLab. Further details on poster - all welcome! 🧠 #neuroscienceseminar #manchesterneuroscience #AlzheimersDisease
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Silencing Apoe with divalent‐siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease alz-journals.onlinelibrary.w…

Silencing Apoe with divalent‐siRNAs improves amyloid burden and activates immune response pathways...

INTRODUCTION The most significant genetic risk factor for late-onset Alzheimer's disease (AD) is APOE4, with evidence for gain- and loss-of-function mechanisms. A clinical need remains for therapeu...

alz-journals.onlinelibrary.wiley.com
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🚨 ISMND 2024 - Registration now open! Join us in Seoul or virtually to discuss recent groundbreaking science in the field of neurodegenerative diseases! Enjoy invited talks by leading experts, short talks, panel discussions & poster presentations bit.ly/4azOK5N
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Fantastic talks so far today at our North West Network Annual Science day! @dementiaunited @ARUKscientist
Neuroscience_MMU@NeuroscienceMmu6 Dec 2023
Great morning here at the North West ARUK Science Day 👏 @ARUK_Manc @ARUKscientist @dementiaunited
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