TB Research // Sassetti Lab // University of Massachusetts Medical School
Worcester, MA
Joined June 2014
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Happy to share the latest from Mike Kiritsy's thesis work - a comparative CRISPR screen identifies a new link between metabolism in immunity, and begins to differentiate the diverse effects of IFNg: elifesciences.org/articles/6…
Our lab has specific opening for a #postdoc interested in studying the regulation of cell growth and division in M. tuberculosis - part of a large program that fosters access to resources throughout the TB research community. Oh, and we just happen to be awesome! #postdocjobs
This small study suggests an important link between antibiotic exposure, carbon metabolism, and culturability. Larger studies are underway to understand the mechanism and clinical importance of these findings
ncbi.nlm.nih.gov/pmc/article…
A great example of our lab's obsession - how immunity shapes Mtb physiology and drug efficacy. Made possible by collaboration with old friends!
journals.plos.org/plospathog…
Another great collaboration with Tom Ioerger and Colleagues at TAMU
cell.com/current-biology/ful…
Sassetti Lab retweeted
Another interesting one from the @SassettiLab! Read more for some cool insights into host immunity, pathogen respiration, and low pH! Some great work by @EJaecklein!!! biorxiv.org/content/10.1101/…
Sassetti Lab retweeted
Thrilled to share our @SassettiLab research investigating how Mycobacterium tuberculosis survives during antibiotic treatment published in @mSystemsJ! msystems.asm.org/content/5/4…
A tremendous effort from Rustin Lovewell et al. reveals the role of granulocytes in tuberculosis:
nature.com/articles/s41385-0…
Congratulations Dr. Bellerose! Thanks to all of our friends and colleagues that joined the Zoom defense.
Congrats to Dr. Bandekar! And thanks to the 143 colleagues that joined his virtual defense. We love this community!
Sassetti Lab retweeted
Someone with active TB may infect as many as 15 people in a year, according to the WHO econ.st/2qS2urQ
Complementary work from Sassetti and Alland labs suggests that high-frequency genetic variation limits TB drug efficacy: mbio.asm.org/content/10/4/e0… and biorxiv.org/content/10.1101/…
Postdoctoral Opportunity in Systems Genetics of Infectious Disease - @Sassettilab.
[email protected] - umassmed.edu/sassettilab/
A great collaboration with the Sacchettini lab: sacclab.com. ncbi.nlm.nih.gov/pubmed/3031…
Congrats to Kenan et al!! Also, thanks to @GHatfull whose dissection of phage recombination systems made ORBIT possible.
