Just a place where I think out loud… 🤯 I can cut your neck for a living.
Hyderabad, India
Joined April 2020
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Vijay Loya retweeted
Epidural lipomatosis
Top: before GLP-1 agonist
Bottom: after GLP-1 agonist
ajronline.org/doi/epdf/10.22…
Vijay Loya retweeted
A 72 year old man in Guntur got a knee replacement in June 2025. Within a month, the artificial joint was infected by Pseudomonas aeruginosa, a bacterium resistant to a wide range of antibiotics, including carbapenems.
Months of washouts, a spacer exchange, an arthroscopy and weeks of intravenous antibiotics followed. By Dec, his pain was 9/10. The infection kept returning. Doctors judged further surgery unsuitable given his age and condition.
The team then tried bacteriophages: viruses that infect specific bacteria.
For those interested in the science, this is where the work gets interesting....
Dr Sutharsan Govindarajan's phage lab at SRM University-AP tested the patient's own bacterial isolate against a panel of phages. 3 were selected and genome-sequenced.
In lab tests, each phage alone initially killed bacteria, but this strain subsequently regrew. The 3 phage cocktail suppressed that regrowth.
The cocktail was delivered into the infected knee through a drainage tube over 10 days. The antibiotic colistin was given alongside from day 2. Lab tests had shown that the combination worked better against this strain than either treatment alone.
- On day 6, colistin was stopped after kidney function worsened. The phage treatment continued.
- By day 10, tests of the joint fluid no longer detected the resistant bacterium. Pain had fallen from 9 to 2-3, and the man could walk independently again. His inflammation marker returned to normal a few days after treatment ended.
- At 6 months, he remained antibiotic-free with no recurrence reported. A joint-fluid culture in June 2026 showed no growth of the pathogen.
The clinical team was led by Dr Kalyan Chakravarthy Koganti at Samishta Hospital (SHRI), Guntur. The authors describe this as, to their knowledge, India's 1st reported successful phage treatment of a carbapenem-resistant prosthetic joint infection.
Bharat is rising. 🙏🙏
Source: B. Sivaraj et al., "Adjunctive Phage Therapy for Carbapenem-Resistant Pseudomonas aeruginosa (CRPA) Prosthetic Knee Joint Infection in India: A Case Report", IJID Regions (2026), available online 14 October. DOI: 10.1016/j.ijregi.2026.101047.
Photo 1: Dr Kalyan Chakravarthy Koganti and the research team. (Credit: T. Vijaya Kumar / The Hindu.)
Photo 2: The actual paper's figure, including the patient's before/after knee photos, antibiotic-resistance results and recovery timeline. via Sivaraj et al., IJID Regions (2026), DOI: 10.1016/j.ijregi.2026.101047.
Vijay Loya retweeted
Paying tribute to Nana Patekar, a remarkable artist whose craft, conviction and unforgettable performances enriched Indian cinema.
Vijay Loya retweeted
I'm giving away 25 copies of #VIBE. To enter, repost and comment by October 13.
adamgrant.net/vibe
Vijay Loya retweeted
Some people sell gold to buy a house. Some sell it for their children’s future. This Delhi man sold family gold passed down from his grandmother and great-grandmother to buy his wife an iPhone 18 Pro Max.🙈
Vijay Loya retweeted
“To be happy you must eliminate two things: The fear of a bad future and the memory of a bad past.”
— Seneca
Vijay Loya retweeted
For years, India depended on imported MRI machines that were expensive, energy-hungry, and out of reach for most hospitals.
Then one Indian engineer decided to change that.
VoxelGrids has built India’s first indigenous MRI scanner, designed and developed entirely in the country. The 1.5-tesla machine is already operational at a cancer care centre in Chandrapur, Maharashtra, quietly marking a major shift in how India approaches medical technology.
What makes it powerful is not just where it’s made, but how it’s built.
The scanner does not use liquid helium, consumes less power, and costs nearly 40 percent less than imported systems.
For hospitals that cannot afford massive upfront investments, VoxelGrids also offers a pay-per-use model, opening access to advanced diagnostics in places that need it most.
Behind this breakthrough is founder Arjun Arunachalam, who left a research career in the US to solve a problem India has lived with for decades.
With support from institutions like Tata Trusts and FISE, the team spent years building, testing, failing, and refining a system designed for Indian realities, not borrowed ones.
This isn’t just about a machine. It’s about bringing quality healthcare closer to people who need it most.
@voxelgrids
#MedTech #StartupIndia #VoxelGrids
[Indigenous MRI scanner, Arjun Arunachalam, VoxelGrids]
Vijay Loya retweeted
When you fear something, learn as much about it as you can. Knowledge conquers fear.
— Edmund Burke
