PleindeSens retweeted
No, @elonmusk, the U.S. stopped funding Ukraine last year. In fact, U.S. companies make money on American weapons for which we Europeans pay.
The more you meddle in our politics and the more you play politics with your products, the more you damage your brand.
PleindeSens retweeted
$NWBO #DCVaxForBraelyn #GBM #glioblastoma
Three induction doses and one booster. Four outpatient visits, a shot in the arm, low-grade fever the most common complaint.
No cytokine storm. No neurotoxicity. No ICU.
Because nothing here overrides her immune system. It teaches it.
Her own dendritic cells, loaded with her own tumor, put back under her own skin. They walk to her lymph node and show her T cells what to hunt. Her body does the rest, and it already knew how.
The UCLA tumor board said amazed.
teapawt.net/i/trending/20997262107…
PleindeSens retweeted
And we have you to thank, Dr. Andrew for help guiding us through this process, answering my tens of thousands of questions and for talking me off the ledge numerous times. We are so grateful for all of your support throughout this journey.
$NWBO #DCVax #GBM
Braelyn's mother said something tonight that deserves to be read twice: promising science means very little if the patients who need it cannot access it.
I made this explainer because her story has a mechanism behind it, and that mechanism turns on one detail most people will read past.
Her tumor tissue was properly preserved.
That is not paperwork.
A dendritic cell vaccine is built from the patient's own tumor, and it has to be whole tumor material, because the immune system's instruction step requires intact protein in order to work at all. A fragment cannot do it. A prediction cannot do it. The tissue is the curriculum, and it exists for a few hours in an operating room and then it is gone forever.
Braelyn nearly lost that window. Not because the science was unavailable, but because nobody told her family it mattered before she went under.
Dr. Liau operated, removed roughly 90% of a tumor spanning three lobes, and the tissue was preserved and sent to England. She has had three induction doses and a booster. Tonight the UCLA tumor board found no visible tumor, including the portion that had to be left behind.
Her radiation, her surgery, her vaccine and her Keytruda are all in that result, and I'm not going to pretend I can separate them. What I can say is that three of those four options were available to her the whole time, and the fourth almost wasn't, for a reason that had nothing to do with biology.
Every glioblastoma patient going to the OR this week faces the same window.
Most of them will never be told it exists.
That is a fixable problem. It should already have been fixed.
No evidence of disease. Congratulations, Braelyn. 🙏🏻
#DCVaxForBraelyn
PleindeSens retweeted
$NWBO #DCVax #GBM
Braelyn's mother said something tonight that deserves to be read twice: promising science means very little if the patients who need it cannot access it.
I made this explainer because her story has a mechanism behind it, and that mechanism turns on one detail most people will read past.
Her tumor tissue was properly preserved.
That is not paperwork.
A dendritic cell vaccine is built from the patient's own tumor, and it has to be whole tumor material, because the immune system's instruction step requires intact protein in order to work at all. A fragment cannot do it. A prediction cannot do it. The tissue is the curriculum, and it exists for a few hours in an operating room and then it is gone forever.
Braelyn nearly lost that window. Not because the science was unavailable, but because nobody told her family it mattered before she went under.
Dr. Liau operated, removed roughly 90% of a tumor spanning three lobes, and the tissue was preserved and sent to England. She has had three induction doses and a booster. Tonight the UCLA tumor board found no visible tumor, including the portion that had to be left behind.
Her radiation, her surgery, her vaccine and her Keytruda are all in that result, and I'm not going to pretend I can separate them. What I can say is that three of those four options were available to her the whole time, and the fourth almost wasn't, for a reason that had nothing to do with biology.
Every glioblastoma patient going to the OR this week faces the same window.
Most of them will never be told it exists.
That is a fixable problem. It should already have been fixed.
No evidence of disease. Congratulations, Braelyn. 🙏🏻
#DCVaxForBraelyn
I have been waiting almost 3 years to write these words:
NO EVIDENCE OF DISEASE. 🙏❤️
Today we met with Braelyn’s neurosurgeon, Dr. Linda Liau at UCLA (telehealth).
When our local radiologist read Braelyn’s August 28 MRI as “no evidence of disease recurrence,” we were thrilled—but I was afraid to fully exhale.
I knew Dr. Liau and the UCLA tumor board would scrutinize every millimeter of those images.
What if they saw something the local radiologist missed?
Today, Dr. Liau told us that she and the tumor board had thoroughly reviewed Braelyn’s MRI.
They were amazed.
There is NO VISIBLE TUMOR.
Even the ~10% Dr. Liau had to leave behind during surgery because of its intimate involvement with critical structures is no longer visible.
She emphasized how amazed and pleased the entire tumor board was by such a complete response at this point.
Her assessment: the prior radiation and the ongoing DCVax appear to be working very well.
Their recommendation after also reviewing the Keytruda regimen Braelyn recently started?
KEEP DOING WHAT SHE’S DOING.
😭🙏
First and foremost, we give ALL thanks and glory to God.
People all over the world have prayed for this girl. I cannot begin to express how humbled and grateful we are.
But tonight I also cannot stop thinking about how close Braelyn came to never having this opportunity.
Earlier this year, her tumor was enormous and growing rapidly.
We sought help from multiple surgeons—including at prestigious institutions.
We were told further surgery was too risky.
We were offered the same old options: chemotherapy and photon radiation that would affect most of her brain, given the size of her tumor.
Her tumor is MGMT-unmethylated, so for Braelyn, chemo was all risk with little to no benefit.
And then a stranger I met here on X changed everything. @ThomasOwenMcCa1 connected us with Dr. Liau.
After reviewing Braelyn’s case, one of the first things she said was:
“This girl needs surgery right away.”
I told her we knew that. We just couldn’t find anyone willing to do it.
I asked if SHE would.
“If you can get her to me, I will do her surgery.”
We got Braelyn to UCLA.
Within two weeks, Dr. Liau operated and removed ~90% of a massive tumor spanning three lobes, stopping where continuing would risk critical structures.
And this time, her tumor tissue was PROPERLY PRESERVED.
That tissue was ultimately sent to England and used to manufacture Braelyn’s personalized DCVax vaccine.
She has now received 3 induction doses + her first booster.
And today?
The tumor that Dr. Liau had to leave behind is no longer visible on MRI.
Think about that.
And then think about what could have happened if we had simply accepted “there’s nothing else we can do.”
THIS is why I will not stop advocating for reform.
Patients should not have to find potentially life-saving treatment options accidentally through strangers on social media.
Patients should be told about legitimate investigational options when standard treatment offers little hope.
Patients undergoing tumor surgery should be informed BEFORE surgery about preservation of tissue that could potentially be used for personalized treatments.
And patients should have the right to make informed decisions about which risks they are willing to take.
Promising science means very little if the patients who need it cannot access it.
Braelyn is living proof of why access matters.
Tonight, though, advocacy can wait for just a moment.
Tonight I’m her mom.
And I finally get to say the words I have begged God to someday let me say:
NO EVIDENCE OF DISEASE.
Thank You, God.
Thank you, Dr. Liau.
Thank you to everyone who opened a door, donated, shared her story, fought for her and prayed for our girl.
There is always light, even in the darkest places.
Tonight that light is shining incredibly bright. ❤️🙏
#DCVaxForBraelyn #CureNotCovered
@greta
@kshaughnessy2
@andrewcaravello
PleindeSens retweeted
I have been waiting almost 3 years to write these words:
NO EVIDENCE OF DISEASE. 🙏❤️
Today we met with Braelyn’s neurosurgeon, Dr. Linda Liau at UCLA (telehealth).
When our local radiologist read Braelyn’s August 28 MRI as “no evidence of disease recurrence,” we were thrilled—but I was afraid to fully exhale.
I knew Dr. Liau and the UCLA tumor board would scrutinize every millimeter of those images.
What if they saw something the local radiologist missed?
Today, Dr. Liau told us that she and the tumor board had thoroughly reviewed Braelyn’s MRI.
They were amazed.
There is NO VISIBLE TUMOR.
Even the ~10% Dr. Liau had to leave behind during surgery because of its intimate involvement with critical structures is no longer visible.
She emphasized how amazed and pleased the entire tumor board was by such a complete response at this point.
Her assessment: the prior radiation and the ongoing DCVax appear to be working very well.
Their recommendation after also reviewing the Keytruda regimen Braelyn recently started?
KEEP DOING WHAT SHE’S DOING.
😭🙏
First and foremost, we give ALL thanks and glory to God.
People all over the world have prayed for this girl. I cannot begin to express how humbled and grateful we are.
But tonight I also cannot stop thinking about how close Braelyn came to never having this opportunity.
Earlier this year, her tumor was enormous and growing rapidly.
We sought help from multiple surgeons—including at prestigious institutions.
We were told further surgery was too risky.
We were offered the same old options: chemotherapy and photon radiation that would affect most of her brain, given the size of her tumor.
Her tumor is MGMT-unmethylated, so for Braelyn, chemo was all risk with little to no benefit.
And then a stranger I met here on X changed everything. @ThomasOwenMcCa1 connected us with Dr. Liau.
After reviewing Braelyn’s case, one of the first things she said was:
“This girl needs surgery right away.”
I told her we knew that. We just couldn’t find anyone willing to do it.
I asked if SHE would.
“If you can get her to me, I will do her surgery.”
We got Braelyn to UCLA.
Within two weeks, Dr. Liau operated and removed ~90% of a massive tumor spanning three lobes, stopping where continuing would risk critical structures.
And this time, her tumor tissue was PROPERLY PRESERVED.
That tissue was ultimately sent to England and used to manufacture Braelyn’s personalized DCVax vaccine.
She has now received 3 induction doses + her first booster.
And today?
The tumor that Dr. Liau had to leave behind is no longer visible on MRI.
Think about that.
And then think about what could have happened if we had simply accepted “there’s nothing else we can do.”
THIS is why I will not stop advocating for reform.
Patients should not have to find potentially life-saving treatment options accidentally through strangers on social media.
Patients should be told about legitimate investigational options when standard treatment offers little hope.
Patients undergoing tumor surgery should be informed BEFORE surgery about preservation of tissue that could potentially be used for personalized treatments.
And patients should have the right to make informed decisions about which risks they are willing to take.
Promising science means very little if the patients who need it cannot access it.
Braelyn is living proof of why access matters.
Tonight, though, advocacy can wait for just a moment.
Tonight I’m her mom.
And I finally get to say the words I have begged God to someday let me say:
NO EVIDENCE OF DISEASE.
Thank You, God.
Thank you, Dr. Liau.
Thank you to everyone who opened a door, donated, shared her story, fought for her and prayed for our girl.
There is always light, even in the darkest places.
Tonight that light is shining incredibly bright. ❤️🙏
#DCVaxForBraelyn #CureNotCovered
@greta
@kshaughnessy2
@andrewcaravello
PleindeSens retweeted
@MarkJCarney is not only the smartest leader of a G-7 nation. He is also potentially the new leader of the Free World, a role model of honesty, intelligence, and visionary thinking. He understands the long arc of history. Bravo @MarkJCarney
PleindeSens retweeted
Mark Carney just delivered Canada's version of Churchill's "we shall never surrender"
I'm so fuckin proud I helped elect this man. I knew he'd be a competent leader, but he's exceeded every expectation
He's the bulwark against the rising tide of fascism. Canada is ready! 🇨🇦
PleindeSens retweeted
For anyone who would like to hear Mark Carney’s outstanding Davos speech in full here it is. This is what true global leadership looks like.
Canada should be immensely proud today, because they are leading the fight back when others dare not.
🎥 TikTok - vm.tiktok.com/ZNRBDT4mB/
PleindeSens retweeted
The Vitamin C Revelation: How a Common Supplement Reshapes Your Gut Microbiome
A clinical discovery by Dr. Sabine Hazan has uncovered a powerful new function of Vitamin C. Beyond its well-known antioxidant role, it appears to be a critical fuel for our beneficial gut bacteria.
While on the front lines treating COVID-19, Dr. Hazan was taking high doses of oral Vitamin C. Subsequent testing revealed a stunning side effect: her levels of Bifidobacteria—a cornerstone of gut health—had quadrupled.
Intrigued, she launched a formal study, analyzing patient stools before and after Vitamin C supplementation. The results, now published, confirmed it: Oral Vitamin C significantly increases Bifidobacteria.
Why does this matter? Bifidobacteria are not passive residents; they are vital for:
- Building a robust immune system
- Fortifying the gut lining
- Combating chronic inflammation
- Synthesizing essential nutrients
This research suggests that one of Vitamin C's most profound benefits may be its prebiotic-like effect, nurturing the microbiome that forms the foundation of our overall health.
It's a paradigm shift in understanding how a simple, accessible nutrient works from the inside out.
PleindeSens retweeted
Tariffs like these raise prices and don't work.
But if you skipped class the day we all learned that – here's a refresher:
PleindeSens retweeted
Scenes from Ontario, Canada....
"Making America Great Again" by making the world hate us and not buy from us.
This is American liquor, produced in Red States, that has been ordered to be taken off the shelves across Ontario.
PleindeSens retweeted
🇨🇳🗣️ Russia and China have instructed their intelligence services to step up the recruitment of U.S. federal employees working in national security, with a particular focus on those who have been fired or believe they may soon be dismissed by Elon Musk and officials in the Trump administration.
Intelligence reports indicate that foreign adversaries are seeking to exploit the Trump administration’s efforts to carry out mass layoffs among federal employees—a plan outlined by the Office of Personnel Management earlier this week.
Russia and China are also targeting recently dismissed employees with security clearances and those on probation who are at risk of being fired, as they may possess valuable information about critical U.S. infrastructure and key government bureaucracy, according to two sources. At least two countries have already launched recruitment websites and begun aggressively targeting federal employees on LinkedIn.
Dictators play chess exceptionally well
PleindeSens retweeted
Watching Trump and Vance gang up and bully Zelensky, I have never been so disgusted and ashamed to be an American in my life. 😡😡😡👇
