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SynapsePapers

@SynapsePapers

Twitterbot bringing you new papers on neuronal synapses. By @ScienceScribe.

Joined February 2015
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Myasthenia gravis: the changing treatment landscape in the era of molecular therapies dlvr.it/T18Nfw
Myasthenia gravis: the changing treatment landscape in the era of molecular therapies - PubMed

Myasthenia gravis: the changing treatment landscape in the era of molecular therapies - PubMed

Myasthenia gravis (MG) is an autoimmune disorder that affects the neuromuscular junction, leading to muscle weakness and fatigue. MG is caused by antibodies against the acetylcholine receptor (AChR),...

pubmed.ncbi.nlm.nih.gov
90
Oligomerization and aggregation of NAP-22 with several metal ions dlvr.it/T13sLl
Oligomerization and aggregation of NAP-22 with several metal ions - PubMed

Oligomerization and aggregation of NAP-22 with several metal ions - PubMed

Metal ions participate in various biochemical processes such as electron transport chain, gene transcription, and enzymatic reactions. Furthermore, the aggregation promoting effect of several metal...

pubmed.ncbi.nlm.nih.gov
83
Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies dlvr.it/T12mNM
Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies -...

Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies -...

Dementia with Lewy bodies (DLB) is a common form of dementia in the elderly population. We performed genome-wide DNA methylation mapping of cerebellar tissue from pathologically confirmed DLB cases...

pubmed.ncbi.nlm.nih.gov
100
Inhibitory CCK+ basket synapse defects in mouse models of dystroglycanopathy dlvr.it/T1163s
Inhibitory CCK+ basket synapse defects in mouse models of dystroglycanopathy - PubMed

Inhibitory CCK+ basket synapse defects in mouse models of dystroglycanopathy - PubMed

Dystroglycan (Dag1) is a transmembrane glycoprotein that links the extracellular matrix to the actin cytoskeleton. Mutations in Dag1 or the genes required for its glycosylation result in dystroglyc...

pubmed.ncbi.nlm.nih.gov
89
CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in Anterior Cingulate Cortex dlvr.it/T0t6Sb
CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in...

CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in...

Previous studies have shown that the C-C motif chemokine ligand 2 (CCL2) is widely expressed in the nervous system and involved in regulating the development of chronic pain and related anxiety-like...

pubmed.ncbi.nlm.nih.gov
91
Heterogeneous presynaptic receptive fields contribute to directional tuning in starburst amacrine cells dlvr.it/T0gHpp
Heterogeneous presynaptic receptive fields contribute to directional tuning in starburst amacrine...

Heterogeneous presynaptic receptive fields contribute to directional tuning in starburst amacrine...

The processing of visual information by retinal starburst amacrine cells (SACs) involves transforming excitatory input from bipolar cells (BCs) into directional calcium output. While previous studies...

pubmed.ncbi.nlm.nih.gov
69
The role of α-synuclein in exocytosis dlvr.it/T0dlzH
The role of α-synuclein in exocytosis - PubMed

The role of α-synuclein in exocytosis - PubMed

The pathogenesis of degeneration in Parkinson's disease (PD) remains poorly understood but multiple lines of evidence have converged on the presynaptic protein α-synuclein (αsyn). αSyn has been shown...

pubmed.ncbi.nlm.nih.gov
83
Phase of neural oscillations as a reference frame for attention-based routing in visual cortex dlvr.it/T0ZJrP
Phase of neural oscillations as a reference frame for attention-based routing in visual cortex -...

Phase of neural oscillations as a reference frame for attention-based routing in visual cortex -...

Selective attention allows the brain to efficiently process the image projected onto the retina, selectively focusing neural processing resources on behaviorally relevant visual information. While...

pubmed.ncbi.nlm.nih.gov
78
Hippocampal proteomic changes in high-fat diet-induced obese mice associated with memory decline dlvr.it/T0ZJqK
Hippocampal proteomic changes in high-fat diet-induced obese mice associated with memory decline -...

Hippocampal proteomic changes in high-fat diet-induced obese mice associated with memory decline -...

Substantial evidence suggest that chronic consumption of high-fat diets (HFDs) can lead to obesity, abnormal metabolism, as well as cognitive impairment. Molecular and cellular changes regarding...

pubmed.ncbi.nlm.nih.gov
1
92
Single-neuron analysis of axon arbors reveals distinct presynaptic organizations between feedforward and feedback projections dlvr.it/T0SSRn
Single-neuron analysis of axon arbors reveals distinct presynaptic organizations between feedforw...

Single-neuron analysis of axon arbors reveals distinct presynaptic organizations between feedforw...

The morphology and spatial distribution of axon arbors and boutons are crucial for neuron presynaptic functions. However, the principles governing their whole-brain organization at the single-neuron...

pubmed.ncbi.nlm.nih.gov
44
Cadherin-13 Maintains Retinotectal Synapses via Trans-Neuronal Interactions dlvr.it/T0QTrC
Cadherin-13 Maintains Retinotectal Synapses via Transneuronal Interactions - PubMed

Cadherin-13 Maintains Retinotectal Synapses via Transneuronal Interactions - PubMed

Maintaining precise synaptic contacts between neuronal partners is critical to ensure the proper functioning of the mammalian central nervous system (CNS). Diverse cell recognition molecules, such as...

pubmed.ncbi.nlm.nih.gov
55
Dopamine transporter membrane mobility is bidirectionally regulated by phosphorylation and palmitoylation dlvr.it/T0Hbdg
Dopamine transporter membrane mobility is bidirectionally regulated by phosphorylation and palmit...

Dopamine transporter membrane mobility is bidirectionally regulated by phosphorylation and palmit...

The primary regulator of dopamine availability in the brain is the dopamine transporter (DAT), a plasma membrane protein that drives reuptake of released dopamine from the extracellular space into...

pubmed.ncbi.nlm.nih.gov
53
Ca2+-regulated expression of high affinity methylaminoisobutryic acid transport in hippocampal neurons inhibited by riluzole and novel neuroprotective aminothiazoles dlvr.it/T0HbdB
Ca2+-regulated expression of high affinity methylaminoisobutryic acid transport in hippocampal...

Ca2+-regulated expression of high affinity methylaminoisobutryic acid transport in hippocampal...

High affinity methylaminoisobutyric acid(MeAIB)/glutamine(Gln) transport activity regulated by neuronal firing occurs at the plasma membrane in mature rat hippocampal neuron-enriched cultures....

pubmed.ncbi.nlm.nih.gov
54
Activity-dependent capture of neuropeptide vesicles prepares clock neuron synapses for daily release dlvr.it/T0Hbb8
Desynchronized Somas and Terminals in a Morning Clock Neuron: Presynaptic Ca2+ Spiking and Native...

Desynchronized Somas and Terminals in a Morning Clock Neuron: Presynaptic Ca2+ Spiking and Native...

Drosophila sLNv clock neurons release the co-packaged neuropeptides PDF and sNPF to regulate circadian behaviors (e.g., morning anticipation) and nighttime sleep1-3. Previous studies of membrane...

pubmed.ncbi.nlm.nih.gov
1
46
Postnatal persistence of hippocampal Cajal-Retzius cells has a critical role in the establishment of the hippocampal circuit dlvr.it/T08NBl
Postnatal persistence of hippocampal Cajal-Retzius cells has a crucial role in the establishment of...

Postnatal persistence of hippocampal Cajal-Retzius cells has a crucial role in the establishment of...

Cajal-Retzius (CR) cells are a transient neuron type that populate the postnatal hippocampus. To understand how the persistence of CR cells influences the maturation of hippocampal circuits, we...

pubmed.ncbi.nlm.nih.gov
52
Hexahydrocurcumin Attenuates Neuronal Injury and Modulates Synaptic Plasticity in Chronic Cerebral Hypoperfusion in Rats dlvr.it/T0468k
Hexahydrocurcumin Attenuates Neuronal Injury and Modulates Synaptic Plasticity in Chronic Cerebral...

Hexahydrocurcumin Attenuates Neuronal Injury and Modulates Synaptic Plasticity in Chronic Cerebral...

Dementia is the most common age-related problem due predominantly to Alzheimer's disease (AD) and vascular dementia (VaD). It has been shown that these contributors are associated with a high amount...

pubmed.ncbi.nlm.nih.gov
54
The exocyst subunit Sec15 is critical for proper synaptic development and function at the Drosophila NMJ dlvr.it/T0468T
The exocyst subunit Sec15 is critical for proper synaptic development and function at the Drosoph...

The exocyst subunit Sec15 is critical for proper synaptic development and function at the Drosoph...

The exocyst protein complex is important for targeted vesicle fusion in a variety of cell types, however, its function in neurons is still not entirely known. We found that presynaptic knockdown (KD)...

pubmed.ncbi.nlm.nih.gov
62
NMJ Analyser: a novel method to quantify neuromuscular junction morphology in zebrafish dlvr.it/T01dQl
NMJ Analyser: a novel method to quantify neuromuscular junction morphology in zebrafish - PubMed

NMJ Analyser: a novel method to quantify neuromuscular junction morphology in zebrafish - PubMed

NMJ Analyser is available for download at https://github.com/PattenLab/NMJ-Analyser.git.

pubmed.ncbi.nlm.nih.gov
58
Connectomic reconstruction predicts the functional organization of visual inputs to the navigation center of the Drosophila brain dlvr.it/T01CRF
Connectomic reconstruction predicts the functional organization of visual inputs to the navigation...

Connectomic reconstruction predicts the functional organization of visual inputs to the navigation...

Many animals, including humans, navigate their surroundings by visual input, yet we understand little about how visual information is transformed and integrated by the navigation system. In Drosoph...

pubmed.ncbi.nlm.nih.gov
52
Adrenergic mechanisms of absence status epilepticus dlvr.it/T005s5
Adrenergic mechanisms of absence status epilepticus - PubMed

Adrenergic mechanisms of absence status epilepticus - PubMed

Absence status epilepticus is a prolonged, generalized absence seizure that lasts more than half an hour. The mechanisms underlying the absence of status epilepticus are still not entirely understo...

pubmed.ncbi.nlm.nih.gov
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